Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: A Study of Pyrotinib Plus Capecitabine Combined With SRT in HER2+ MBC With Brain Metastases [Phase 2]
Phase 2 trial update evaluating pyrotinib plus capecitabine with stereotactic radiotherapy in HER2-positive metastatic breast cancer with br…
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CLINICAL_TRIALS trial_result · 2023-12-22Clinical Trial Update: Atezolizumab + Stereotactic Radiation in Triple-negative Breast Cancer and Brain Metastasis [Phase 2]
Phase 2 trial assessing atezolizumab plus stereotactic radiation for triple-negative breast cancer with brain metastases has completed enrol…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Study of Cadonilimab Combined With Bevacizumab and Chemotherapy for Advanced Nonsquamous Non-small Cell Lung Cancer Patients With Untreated Brain Metastases [Phase 2]
Phase 2 trial exploring cadonilimab with bevacizumab and chemotherapy for advanced non-squamous non-small cell lung cancer with untreated br…
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CLINICAL_TRIALS trial_result · 2023-11-01Clinical Trial Update: Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Study [Phase 2]
Phase 2 open-label trial assessing losartan with imaging perfusion restrictions related to extracellular solid stress in glioblastoma and br…
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CLINICAL_TRIALS trial_result · 2023-10-30Clinical Trial Update: Tumor Treating Fields (TTFields) Therapy to Manage Brain Metastases in Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating Tumor Treating Fields (TTFields) therapy for brain metastases in small cell lung cancer; the study was terminated w…
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: Stereotactic Radiosurgery vs Whole Brain Radiotherapy in Breast Cancer With Brain Oligometastasis [Phase 3]
Phase 3 trial comparing stereotactic radiosurgery versus whole brain radiotherapy in breast cancer with brain oligometastases.
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Study of Intraoperative Radiotherapy for Patients With Large Brain Metastases Treated With Neurosurgical Resection [NA]
A terminated clinical trial investigating intraoperative radiotherapy for patients with large brain metastases post-neurosurgical resection;…
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CLINICAL_TRIALS trial_result · 2023-09-25Clinical Trial Update: A Study of Pyrotinib Plus Capecitabine in Patients With Brain Metastases From HER2-positive Metastatic Breast Cancer [Phase 2]
A Phase 2 clinical trial evaluating pyrotinib plus capecitabine for brain metastases in HER2-positive metastatic breast cancer.
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: Study to Establish Image Interpretation Criteria for 18F Fluciclovine PET in Detecting Recurrent Brain Metastases (PURSUE) [Phase 2]
Phase 2 study PURSUE has completed and its results have been posted. It aims to establish image interpretation criteria for 18F-fluciclovine…
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CLINICAL_TRIALS trial_result · 2023-07-28Clinical Trial Update: Preoperative SRS/SRT vs Postoperative SRS/SRT for Brain Metastases [NA]
A terminated clinical trial comparing preoperative versus postoperative stereotactic radiosurgery/radiation therapy for brain metastases; re…
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread [Phase 1]
This Phase 1 trial evaluates adding Entinostat to standard chemo-immunotherapy (atezolizumab, carboplatin, etoposide) for previously untreat…
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CLINICAL_TRIALS research · 2023-06-01Clinical Trial Update: nTMS for Motor Mapping of Rolandic Lesions [Phase 2, Phase 3]
Clinical trial update on navigated transcranial magnetic stimulation (nTMS) for motor mapping in Rolandic region lesions, with Phase 2 and P…
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CLINICAL_TRIALS trial_result · 2023-05-31Clinical Trial Update: An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis [Phase 2]
Phase 2 open-label trial evaluating standard-dose vs high-dose encorafenib + binimetinib in BRAFV600-mutant melanoma with brain metastases; …
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CLINICAL_TRIALS trial_result · 2023-05-25Clinical Trial Update: Tislelizumab Combined With Pemetrexed/ Carboplatin in Patients With Brain Metastases of Non-squamous NSCLC [Phase 2]
Phase 2 trial evaluating tislelizumab in combination with pemetrexed and carboplatin for brain metastases in non-squamous non-small cell lun…
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CLINICAL_TRIALS trial_result · 2023-05-19Clinical Trial Update: Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors [Phase 1]
Phase 1 study evaluating the safety of the CHK1 inhibitor VX-970 (M6620) in combination with whole-brain radiation therapy for brain metasta…
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CLINICAL_TRIALS trial_result · 2023-04-24Clinical Trial Update: ANG1005 in Leptomeningeal Disease From Breast Cancer [Phase 3]
Phase 3 clinical trial update for ANG1005 in leptomeningeal disease from breast cancer (leptomeningeal carcinomatosis/metastases).
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases [Phase 3]
Phase 3 trial investigating early or delayed brain radiotherapy combined with almonertinib in EGFR-mutated non-small cell lung cancer with b…
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CLINICAL_TRIALS trial_result · 2023-01-27Clinical Trial Update: Open-label PET Study With [11C]Osimertinib in Patients With EGFRm NSCLC and Brain Metastases [Phase 1]
Phase 1 open-label trial investigating [11C]Osimertinib in EGFR-mutant NSCLC with brain metastases; results posted after completion.
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CLINICAL_TRIALS trial_result · 2023-01-18Clinical Trial Update: Pyrotinib Combined With Brain Radiotherapy in Breast Cancer Patients With Brain Metastases [Phase 1, Phase 2]
A clinical trial evaluating pyrotinib combined with brain radiotherapy for patients with breast cancer and brain metastases (Phase 1/2).
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CLINICAL_TRIALS trial_result · 2023-01-04Clinical Trial Update: Radiosurgery Plus NovoTTF-200A for Metastatic Small Cell Lung Cancer to the Brain [NA]
Clinical trial update for radiosurgery plus NovoTTF-200A in metastatic small cell lung cancer to the brain; the study is terminated with pos…
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CLINICAL_TRIALS trial_result · 2022-12-13Clinical Trial Update: Fractionated Stereotactic Radiotherapy vs. Single Session Radiosurgery in Patients With Larger Brain Metastases [Phase 3]
Phase 3 trial comparing fractionated stereotactic radiotherapy to single-session radiosurgery for larger brain metastases, currently recruit…
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CLINICAL_TRIALS trial_result · 2022-11-16Clinical Trial Update: Camrelizumab With AC in Patients With Brain Metastases of Driven Gene-negative,NSCLC [Phase 2]
Phase 2 trial evaluating camrelizumab with AC chemotherapy in brain metastases from driven gene-negative non-squamous non-small-cell lung ca…
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CLINICAL_TRIALS trial_result · 2022-11-08Clinical Trial Update: DM-CHOC-PEN for Brain Tumors in AYA Subjects [Phase 2]
Phase 2 trial update for DM-CHOC-PEN in adolescents and young adults with brain tumors, completed.
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Stereotactic Radiotherapy of the Resection Cavity of Brain Metastases vs. Post-operative Whole-brain Radiotherapy [Phase 2]
Phase 2 clinical trial comparing stereotactic radiotherapy of the resection cavity to post-operative whole-brain radiotherapy for brain meta…
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CLINICAL_TRIALS trial_result · 2022-10-24Clinical Trial Update: Brigatinib Before Brain Irradiation Trial (B3i Trial) [Phase 2]
Phase 2 trial update for brigatinib before brain irradiation in patients with brain metastases and lung cancer has been terminated; results …