Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-10-20Clinical Trial Update: Dose-escalation by Hypofractionated Stereotactic Radiotherapy for Brain Metastases in Non Small Cell Lung Cancer [Phase 1, Phase 2]
A dose-escalation trial is investigating hypofractionated stereotactic radiotherapy for brain metastases in patients with non-small cell lun…
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CLINICAL_TRIALS trial_result · 2022-09-21Clinical Trial Update: Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593) [Phase 1, Phase 2]
Phase 1/2 trial evaluating glyburide vs placebo to prevent cerebral edema in patients undergoing radiosurgery for brain metastases; the stud…
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CLINICAL_TRIALS trial_result · 2022-08-10Clinical Trial Update: Pembrolizumab and Magnetic Resonance Imaging With Ferumoxytol in Treating Patients With Non-small Cell Lung Cancer and Brain Metastases [Phase 2]
Phase 2 trial update evaluating pembrolizumab with ferumoxytol-enhanced MRI in patients with non-small cell lung cancer and brain metastases…
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CLINICAL_TRIALS trial_result · 2022-07-26Clinical Trial Update: Neoadjuvant Immunotherapy in Brain Metastases [Phase 2]
Phase 2 neoadjuvant immunotherapy trial in adults with brain metastases was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-04-08Clinical Trial Update: SIMT Stereotactic Radiosurgery Outcomes Study [NA]
Completed clinical trial update for SIMT Stereotactic Radiosurgery Outcomes Study; results posted.
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: Gefitinib With or Without Chemotherapy in Brain Metastases From Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating gefitinib with or without chemotherapy in brain metastases from non-small cell lung cancer is ongoing; results not …
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CLINICAL_TRIALS trial_result · 2022-02-16Clinical Trial Update: Hippocampal-Sparing Stereotactic Radiosurgery Treatment of Brain Metastases Using CyberKnife [Phase 2]
Phase 2 clinical trial update for hippocampal-sparing stereotactic radiosurgery of brain metastases using CyberKnife.
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CLINICAL_TRIALS trial_result · 2022-02-08Clinical Trial Update: Apatinib Combined With Radiotherapy in Patient With BM From Drive Gene Negative NSCLC [Phase 2]
Phase 2 trial assessing apatinib combined with radiotherapy in brain metastases from driver-gene negative non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2022-02-01Clinical Trial Update: STAR Cape+BKM120 MBC With Brain Met [Phase 2]
A Phase 2 clinical trial update for STAR Cape+BKM120 in metastatic breast cancer with brain metastases has completed enrollment with results…
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CLINICAL_TRIALS trial_result · 2022-01-26Clinical Trial Update: Tislelizumab Plus Chemotherapy as First-Line Treatment for Advanced Squamous NSCLC With Brain Metastases [Phase 2]
Phase 2 trial investigating tislelizumab plus chemotherapy as first-line treatment for advanced squamous non-small cell lung cancer with bra…
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CLINICAL_TRIALS trial_result · 2021-11-23Clinical Trial Update: Phase 2 Study of Study of Tesevatinib in Subjects With NSCLC and Brain or Leptomeningeal Metastases [Phase 2]
Phase 2 study of tesevatinib in subjects with non-small cell lung cancer and brain or leptomeningeal metastases has completed; results poste…
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CLINICAL_TRIALS trial_result · 2021-09-10Clinical Trial Update: Camrelizumab Combined With Local Treatment in NSCLC Patients With BM [Phase 2]
Phase 2 trial update examining camrelizumab plus local treatment in stage IV non-small cell lung cancer with brain metastases.
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases [Phase 2]
Phase 2 trial evaluating radiation therapy combined with thalidomide and temozolomide for patients with newly diagnosed brain metastases is …
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: HA-WBRT vs SRS in Patients With Multiple Brain Metastases [Phase 3]
Phase 3 clinical trial comparing HA-WBRT to SRS in patients with multiple brain metastases is ongoing; current status is unknown.
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CLINICAL_TRIALS trial_result · 2021-08-27Clinical Trial Update: A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine [Phase 3]
Phase 3 trial comparing etirinotecan pegol (NKTR-102) to physician's choice in metastatic breast cancer with stable brain metastases; study …
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CLINICAL_TRIALS trial_result · 2021-08-23Clinical Trial Update: Radiation Therapy With or Without RSR13 in Treating Patients With Brain Metastases [Phase 3]
Phase 3 trial evaluating radiation therapy with or without RSR13 in patients with brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2021-08-17Clinical Trial Update: Concurrent Dabrafenib + Trametinib With Sterotactic Radiation in BRAF Mutation-Positive Malignant Melanoma and Brain Metastases [Phase 2]
Phase 2 trial investigating concurrent dabrafenib and trametinib with stereotactic radiotherapy for BRAF mutation-positive melanoma with bra…
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CLINICAL_TRIALS trial_result · 2021-08-06Clinical Trial Update: Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases [Phase 2]
Phase 2 trial comparing corticosteroids plus bevacizumab versus corticosteroids plus placebo for radionecrosis after radiosurgery in patient…
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CLINICAL_TRIALS trial_result · 2021-07-29Clinical Trial Update: A Proof-of-principle Study of HBO-SRS for Brain Metastases [NA]
A proof-of-principle study evaluating HBO-SRS for brain metastases has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-07-27Clinical Trial Update: the Efficacy and Safety of Anlotinib Combined With Almonertinib in the First-line Treatment of Patients With Brain Metastases From EGFR Mutation-positive Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of anlotinib and almonertinib as first-line therapy for brain metastases in EGFR mutation-…
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CLINICAL_TRIALS trial_result · 2021-07-01Clinical Trial Update: GEM STUDY: Radiation And Yervoy in Patients With Melanoma and Brain Metastases [Phase 2]
Phase 2 trial evaluating the combination of Radiation and Yervoy (ipilimumab) in melanoma patients with brain metastases has completed with …
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: TKIs vs. Pertuzumab in HER2+ Breast Cancer Patients With Active Brain Metastases (HER2BRAIN) [Phase 2]
Phase 2 trial comparing tyrosine kinase inhibitors versus pertuzumab in HER2-positive breast cancer with active brain metastases is ongoing …
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CLINICAL_TRIALS trial_result · 2021-05-07Clinical Trial Update: Bevacizumab, Etoposide and Cisplatin Followed by Whole Brain Radiotherapy in Breast Cancer With Brain Metastases [Phase 2]
Phase 2 trial evaluating bevacizumab, etoposide, and cisplatin followed by whole brain radiotherapy for breast cancer with brain metastases.
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases [Phase 2]
Phase 2 trial update examining neurocognitive outcomes with bilateral or unilateral hippocampal-avoidance whole-brain radiotherapy plus mema…
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases [Phase 2]
Phase 2 trial comparing hippocampal-sparing whole brain radiotherapy to conventional whole brain radiotherapy for brain metastases has compl…