Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases [Phase 2]
Phase 2 clinical trial update evaluating the combination of radiosurgery and nivolumab for brain metastases in various cancers, with complet…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Pilot Phase 2 Study Whole Brain Radiation Therapy With Simultaneous Integrated Boost for Patients With Brain Metastases [NA]
The pilot Phase 2 trial evaluating whole brain radiation therapy with simultaneous integrated boost for brain metastases was terminated; res…
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: SRT Combined With Anlotinib for the Treatment of Brain Metastases From Non-small Cell Lung Cancer [NA]
This clinical trial is evaluating the combination of stereotactic radiotherapy (SRT) with anlotinib for brain metastases from non-small cell…
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CLINICAL_TRIALS research · 2024-06-18Clinical Trial Update: UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases [Phase 2]
A Phase 2 trial at UCSD is evaluating image-guided, cognitive-sparing radiosurgery for brain metastases. The study is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Sacituzumab Govitecan Combined With Head Radiotherapy for Her2-negative Breast Cancer Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating sacituzumab govitecan combined with brain radiotherapy for HER2-negative breast cancer with brain metast…
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Radiotherapy of Multiple Brain Metastases Using AGuIX® [Phase 2]
A Phase 2 clinical trial is evaluating radiotherapy for multiple brain metastases using the AGuIX nanoparticle radiosensitizer. The current …
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CLINICAL_TRIALS research · 2024-05-30Clinical Trial Update: Immune Treatment of Brain Metastasis of Lung Cancer Combined With Large-segmentation Precision Radiotherapy [Phase 2]
A Phase 2 clinical trial in non-small cell lung cancer with brain metastases is currently recruiting, evaluating an immune therapy in combin…
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CLINICAL_TRIALS withdrawal · 2024-05-29Clinical Trial Update: JDQ443 for KRAS G12C NSCLC Brain Metastases [Phase 2]
A Phase 2 trial of JDQ-443 for KRAS G12C-mutant non-small cell lung cancer with brain metastases has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases [EARLY_Phase 1]
This early-phase trial evaluates 18F-FMAU PET/CT with MRI to detect brain tumors in patients with brain cancer or brain metastases. The stud…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Closed vs. Open Face Masks for Cranial Radiotherapy [NA]
This clinical trial update notes the completion of a study comparing closed versus open face masks for cranial radiotherapy in patients with…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: HKI-272 for HER2-Positive Breast Cancer and Brain Metastases [Phase 2]
Phase 2 trial update for neratinib (HKI-272) in HER2-positive breast cancer with brain metastases; the study completed and results have been…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Imaging Features for the Risks for Recurrence After Stereotactic Radiosurgery in Brain Metastasis
A recruiting trial evaluating imaging features to assess the risk of recurrence after stereotactic radiosurgery for brain metastases.
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: A Retrospective Study of the Efficacy and Safety of Lolatinib in ALK+ NSCLC Patients With Brain or Meningeal Metastasis
A retrospective study evaluating the efficacy and safety of Lolatinib in ALK-positive non-small cell lung cancer patients with brain metasta…
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Cilengitide and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Lung Cancer [Phase 1]
A Phase 1 trial evaluating cilengitide in combination with whole-brain radiation therapy for brain metastases arising from lung cancer has b…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: SGM-101 in Colorectal Brain Metastases. [Phase 2]
Phase 2 clinical trial evaluating SGM-101 for colorectal cancer with brain metastases is currently recruiting at Leiden University Medical C…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Neoadjuvant vs. Intraoperative vs. Adjuvant Resection Cavity Radiotherapy of Brain Metastases [Phase 2]
A Phase 2 study comparing neoadjuvant, intraoperative, and adjuvant resection cavity radiotherapy for brain metastases is currently recruiti…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Magnetic Resonance Imaging-guided Adaptive Radiotherapy for Large Brain Metastases
This document provides an update on an ongoing clinical trial evaluating magnetic resonance imaging-guided adaptive radiotherapy for patient…
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: LIFE - Lung Cancer, Immunotherapy, Frailty, Effect
The LIFE trial update describes a study of non-small cell lung cancer examining immunotherapy with attention to frailty and quality-of-life …
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Nivo/Ipi Combination Therapy in Symptomatic Brain Metastases [Phase 2]
Phase 2 clinical trial evaluating the nivolumab and ipilimumab combination in symptomatic melanoma with brain metastases has been terminated…
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Dual Time Point FDG PET/MRI Scan in Improving the Imaging Cancer Patients With Brain Metastases [Phase 4]
Phase 4 clinical trial assessing a dual time-point FDG PET/MRI protocol to improve imaging of brain metastases; trial status is completed.
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Frameless Fractionated Stereotactic Radiation in Treating Patients With Brain Metastases [Phase 2]
Phase 2 clinical trial update evaluating frameless fractionated stereotactic radiation for brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases [Phase 2]
A Phase 2 trial investigating chemotherapy plus atezolizumab for extensive-stage small cell lung cancer with untreated asymptomatic brain me…
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Pembrolizumab In Central Nervous System Metastases [Phase 2]
Phase 2 clinical trial update for pembrolizumab in patients with brain metastases (central nervous system involvement).
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CLINICAL_TRIALS trial_result · 2024-03-01Clinical Trial Update: HA-WBRT-SIB for Brain Metastasis of Lung Cancer [Phase 2]
Phase 2 trial update on HA-WBRT-SIB for brain metastases from lung cancer; study completed.
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases [Phase 1]
Phase 1 clinical trial evaluating ropidoxuridine with whole brain radiation therapy for brain metastases; status is ACTIVE_NOT_RECRUITING wi…