Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases [NA]
This clinical trial update describes a study evaluating stereotactic radiation for patients with small cell lung cancer and 1–10 brain metas…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial [NA]
A Phase III randomized trial comparing hippocampal-sparing whole-brain radiation versus stereotactic radiation in patients with 5-20 brain m…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Advanced MRI Scan Before and After Radiation Therapy for the Detection of Intracranial Metastasis [NA]
Clinical trial results assess the use of advanced MRI before and after radiation therapy to detect intracranial metastases in patients with …
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Pembro+Chemo in Brain Mets [Phase 2]
Phase 2 trial of pembrolizumab plus chemotherapy for brain metastases from lung cancer was terminated, with results posted.
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CLINICAL_TRIALS research · 2024-10-16Clinical Trial Update: Antirotinib Hydrochloride Plus Whole Brain Radiotherapy for Small Cell Lung Cancer With Brain Metastases [Phase 2]
Phase 2 clinical trial evaluating antirotiinib hydrochloride in combination with whole brain radiotherapy for small cell lung cancer with br…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: BEAT-Breast: Trial of DE-iPTV in Patients With Primary Breast Cancer With Brain Metastases Who Are Not Suitable for Stereotactic Radiotherapy. [NA]
BEAT-Breast is a clinical trial evaluating DE-iPTV for breast cancer with brain metastases in patients unsuitable for stereotactic radiother…
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery [Phase 1]
APN401 was evaluated in a Phase 1 trial for patients with recurrent or metastatic pancreatic cancer, colorectal cancer, and unresectable sol…
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: Blood Brain Barrier Differences in Patients with Brain Tumors Undergoing Surgery
This completed clinical trial examined differences in the blood-brain barrier in patients with brain tumors undergoing surgical resection.
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy [EARLY_Phase 1]
A phase 1 study from Vanderbilt-Ingram Cancer Center is evaluating image-based, in-vivo assessment of tumor hypoxia to guide hypoxia-driven …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Single-arm, Prospective Phase Ⅱ Clinical Study of Utidelone Combined with Capecitabine in the Treatment of Active Brain Metastasis of TNBC [Phase 2]
A single-arm, prospective Phase II trial assessing Utidelone plus capecitabine for active brain metastases in triple-negative metastatic bre…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Radiosurgery Dose Reduction for Brain Metastases on Immunotherapy (RADREMI): A Prospective Pilot Study [NA]
RADREMI was a prospective pilot study evaluating dose reduction of radiosurgery for brain metastases in patients receiving immunotherapy; th…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Low Dose Versus Standard Dose Dexamethasone for Reduction of Swelling in Patients with Primary or Metastatic Brain Tumors [Phase 2]
Phase 2 trial comparing low-dose versus standard-dose dexamethasone to reduce swelling in patients with malignant brain neoplasms and brain …
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: JK-1201I in Triple Negative Breast Cancer Patients with Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating JK-1201I in patients with triple-negative breast cancer and brain metastases; the study is not yet recru…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Active Brain Metastasis [Phase 2]
A Phase 2 clinical trial from Fudan University evaluates cranial radiotherapy combined with chemoimmunotherapy for untreated driver-mutation…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Stable Brain Metastasis [Phase 2]
A Phase 2 clinical trial update on cranial radiotherapy combined with chemoimmunotherapy for untreated driver-mutation negative non-small ce…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Comparaison Between MRI Alone or Combined With Positron Emission Tomography for Brain Metastasis Diagnosis
A completed clinical trial compared MRI alone to MRI combined with PET for diagnosing brain metastases, assessing whether adding PET improve…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Stereotactic Radiotherapy Management of Brain Metastases: the Value of a Longitudinal Multimodal Approach (POSTPONE)
This clinical trial update outlines a study on stereotactic radiotherapy management of brain metastases using a longitudinal multimodal appr…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Intraoperative Laser Speckle Contrast Imaging of Cerebral Blood Flow
Clinical trial update on using intraoperative laser speckle contrast imaging to monitor cerebral blood flow during brain procedures across s…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: GM1 Prophylaxis for WBRT Related Cognitive Dysfunction [Phase 3]
A Phase 3 trial evaluating GM1 ganglioside prophylaxis to prevent whole-brain radiotherapy-related cognitive dysfunction in patients with br…
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CLINICAL_TRIALS other · 2024-07-19Clinical Trial Update: Evaluation of Brain Metastases Treated With Stereotactic Radiotherapy Using Dynamic [18F]FDG PET [NA]
This clinical trial update notes a study evaluating brain metastases treated with stereotactic radiotherapy and dynamic [18F]FDG PET; the tr…
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CLINICAL_TRIALS research · 2024-07-18Clinical Trial Update: A Phase II Study of Triple-negative Breast Cancer Brain Metastases. [Phase 2]
A Phase II clinical trial evaluating treatment for brain metastases in patients with triple-negative breast cancer, currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Hypofractionated Brain Radiationcavity [NA]
Clinical trial update indicates the hypofractionated brain radiation trial for brain metastases has completed; no results are provided in th…
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: Pre-operative Stereotactic Radiosurgery Followed by Resection for Patients With Brain Metastases [NA]
This clinical trial update notes that a study evaluating pre-operative stereotactic radiosurgery followed by surgical resection for brain me…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Metachronic Brain Metastases After Esophagectomy for Esophageal Cancer (METABREC)
METABREC (NCT04654975) is a clinical trial investigating brain metastases after esophagectomy for esophageal cancer. The study is currently …
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: Local Ablative Therapy for Patients With Multiple (4-10) Brain Metastases
This clinical trial entry reports recruiting status for a study on local ablative therapy for patients with multiple brain metastases (4-10 …