Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease [Phase 2]
Phase 2 results update for DS-8201a (trastuzumab deruxtecan) in advanced HER2-positive breast cancer, including patients with brain metastas…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Diagnostic Assessment of Amino Acid PET/MRI in the Evaluation of Glioma and Brain Metastases
This clinical trial is evaluating amino acid PET/MRI for the evaluation of glioma and brain metastases. The study is currently recruiting an…
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CLINICAL_TRIALS withdrawal · 2025-06-15Clinical Trial Update: A Window of Opportunity Study of Patritumab Deruxtecan in Patients With Brain Metastases [Phase 2]
A Phase 2 study evaluating patritumab deruxtecan for brain metastases has been withdrawn from ClinicalTrials.gov.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Glutamate Excitotoxicity in Brain Metastases From Lung, Breast and Melanoma Treated With Stereotactic Radiosurgery
ClinicalTrials.gov entry for a study on glutamate excitotoxicity in brain metastases from lung cancer, breast cancer, and melanoma treated w…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Characterization of Circulating and Tumor-infiltrating Immune Cells in Malignant Brain Tumors
A recruiting clinical trial characterizes circulating and tumor-infiltrating immune cells in malignant brain tumors to study the immune envi…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery [Phase 3]
Phase 3 trial comparing hippocampus-sparing whole-brain radiotherapy to stereotactic radiosurgery for patients with brain metastases from va…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Intraoperative Radiotherapy in Patients With Brain Metastases [NA]
ClinicalTrials.gov updates a study evaluating intraoperative radiotherapy for brain metastases, currently in the recruitment phase.
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: A Ketogenic Diet as a Complementary Treatment on Patients With High-grade Gliomas and Brain Metastases [NA]
A clinical trial at Attikon Hospital is evaluating the ketogenic diet as a complementary treatment for patients with high-grade gliomas and …
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: RTA 744 in Breast Cancer Patients With Progression of Previously Irradiated Brain Metastases [Phase 2]
Phase 2 trial of RTA 744 in breast cancer patients with progression of previously irradiated brain metastases has been terminated.
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Efficacy of the Association of Fractionated SRS and Subsequent Surgery in Patients With Brain Metastases [NA]
This clinical trial update reports on the efficacy of using fractionated stereotactic radiosurgery followed by surgery for brain metastases;…
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CLINICAL_TRIALS trial_result · 2025-05-28Clinical Trial Update: Fractionated Stereotactic Radiosurgery for Large Brain Metastases [NA]
Clinical trial update reporting results for fractionated stereotactic radiosurgery in patients with large brain metastases; results were pos…
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CLINICAL_TRIALS withdrawal · 2025-05-26Clinical Trial Update: Cemiplimab for the Treatment of Untreated Brain Metastases From PD-L1 >= 50% Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating cemiplimab for untreated brain metastases in patients with PD-L1 >= 50% non-small cell lung cancer has been withd…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Phase I Study of Fractionated Stereotactic Radiation Therapy [Phase 1]
Phase I study evaluating fractionated stereotactic radiation therapy for Brain metastases. The trial is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Whole Brain Radiation Using IMRT for Patients With Brain Metastases [NA]
The clinical trial evaluating whole-brain radiation therapy using IMRT for brain metastases has completed.
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: 18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery [Phase 1]
A Phase 1 clinical trial evaluating 18F-fluciclovine PET imaging for brain metastases treated with stereotactic radiosurgery is currently re…
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: A Dose Escalation Trial of Five Fraction Stereotactic Radiation Therapy for Brain Metastases [NA]
This completed dose-escalation trial studied five-fraction stereotactic radiation therapy for brain metastases, and results have been posted…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain Metastases [NA]
Clinical trial comparing intraoperative sonography to fluorescence-guided resection for contrast-enhancing gliomas and brain metastases has …
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas [NA]
A clinical trial comparing general anesthesia versus awake surgery for resection of gliomas and brain metastases in motor cortex regions; th…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases [NA]
This clinical trial update reports a recruitment-status study (NCT05474573) evaluating fluorescence- and ultrasound-guided eradication of co…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Avoiding Radiation Therapy Due to Intracranial Response to Chemotherapy, Targeted Therapy and/or Immuno-ONcology Therapy for Brain Metastases: Pilot Pragmatic Trial [Phase 2]
This is a Phase 2 pilot pragmatic clinical trial updating on strategies to avoid radiation therapy for brain metastases in NSCLC patients wh…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery [NA]
Clinical trial is currently recruiting to study neurocognition in patients with brain metastases treated with radiosurgery.
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Survivorship Study of Cancer Patients Who Received Cranial Radiation Therapy
This clinical trial update reports that the Duke University–sponsored survivorship study of cancer patients who received cranial radiation t…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Encorafenib and Binimetinib Before Local Treatment in Patients With BRAF Mutant Melanoma Metastatic to the Brain [Phase 2]
Phase 2 study evaluating encorafenib and binimetinib before local treatment in patients with BRAF-mutant melanoma that has spread to the bra…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Stereotactic Radiosurgery Dose Escalation for Brain Metastases [Phase 1]
Phase 1 clinical trial evaluating dose-escalation stereotactic radiosurgery for brain metastases is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases [Phase 2]
Phase 2 clinical trial update on Sacituzumab Govitecan in combination with Bevacizumab for non-small cell lung cancer with brain metastases.…