Amyotrophic Lateral Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: New Therapeutic Strategy in ALS Based on Metabolic Status and Associated Metabolic Pathways. [NA]
A completed clinical trial update describes a metabolic-status–driven therapeutic strategy for amyotrophic lateral sclerosis. The study was …
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: ALS Phase II Study of NX210c [Phase 2]
A Phase II clinical trial of NX210c for Amyotrophic Lateral Sclerosis is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Combined Respiratory Training in Persons With ALS [NA]
Clinical trial update for a combined respiratory training program in persons with amyotrophic lateral sclerosis. The study is currently recr…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Tongue-strengthening Exercises in People With ALS. [NA]
A clinical trial sponsored by Nova Southeastern University is evaluating tongue-strengthening exercises in people with amyotrophic lateral s…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Muscular Biomarkers in Amyotrophic Lateral Sclerosis [NA]
This update reports a completed clinical trial investigating muscular biomarkers in Amyotrophic Lateral Sclerosis.
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Ocular Surface Metabolo-lipidomics in Lateral Amyotrophic Sclerosis [NA]
A completed clinical trial evaluating ocular surface metabolo-lipidomics in individuals with amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS [Phase 2]
Open-label extension update for a Phase 2 study evaluating CNM-Au8 in early symptomatic ALS patients on stable background therapy to slow di…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: A Study of STRO4 in Patients Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
A Phase 2 study of STRO4 in patients with amyotrophic lateral sclerosis has been terminated. The entry notes sponsor and trial status but do…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Video-Based Proprioceptive Exercise Program in ALS [NA]
Clinical trial evaluating a video-based proprioceptive exercise program for amyotrophic lateral sclerosis; the study is currently recruiting…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Extension Study of Participants From SPG302-ALS-001 [Phase 2]
An extension study of SPG302-ALS-001 in participants with amyotrophic lateral sclerosis has been terminated.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders
This clinical trial update describes a biospecimen biorepository study for amyotrophic lateral sclerosis, ALS-FTD, and related neurodegenera…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Study of VRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS) [Phase 1]
A Phase 1 study of VRG50635 for amyotrophic lateral sclerosis has been terminated.
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Lung Insufflation Capacity Training and Respiratory Function in Amyotrophic Lateral Sclerosis [NA]
Clinical trial update on lung insufflation capacity training and respiratory function in amyotrophic lateral sclerosis, currently recruiting…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Translating Single-cell Vulnerability Into Novel ALS Biomarkers and Therapeutic Targets: Towards a Liquid Nerve Biopsy
Clinical trial aiming to translate single-cell vulnerability into novel biomarkers and therapeutic targets for amyotrophic lateral sclerosis…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Conservative Iron Chelation as a Disease-modifying Strategy in Amyotrophic Lateral Sclerosis [Phase 2, Phase 3]
This document reports a Phase 2/Phase 3 clinical trial evaluating conservative iron chelation as a disease-modifying strategy for amyotrophi…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Continuous Measurement of Activity in Patients With Muscle Pathology and in Control Subjects. ActiSLA Part. [NA]
A clinical trial evaluating continuous measurement of activity in patients with muscle pathology and in control subjects, focusing on amyotr…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: MIROCALS: Modifying Immune Response and OutComes in ALS [Phase 2]
MIROCALS is a Phase 2 trial aimed at modifying immune response and outcomes in amyotrophic lateral sclerosis; the study has completed.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease. [NA]
This clinical trial update reports a currently recruiting study evaluating whether electrical stimulation affects facial pain, jaw movement,…
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CLINICAL_TRIALS other · 2025-12-03Clinical Trial Update: The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder [NA]
A clinical trial evaluating a muscle-mimicking fabric-type shoulder orthosis to improve upper-limb movements in patients with neuromuscular …
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia [NA]
This document provides an update on BrainGate2, a feasibility study of an intracortical neural interface system for people with tetraplegia,…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Comprehensive Biomarker Profiling of the IFN-α Pathway in Amyotrophic Lateral Sclerosis Patient Biofluids
Completed clinical trial investigating biomarkers of the interferon-alpha pathway in Amyotrophic Lateral Sclerosis patient biofluids.
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia [NA]
This update describes a feasibility study of the BrainGate2 neural interface system in people with tetraplegia and related conditions, with …
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD [Phase 2]
Phase 2 study evaluating safety and therapeutic potential of metformin for C9orf72-related ALS/FTD, with results posted in December 2025.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Imaging Biomarkers in ALS
The University of Minnesota is recruiting participants for a study on imaging biomarkers in amyotrophic lateral sclerosis and primary latera…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02) [NA]
This update describes a feasibility study of the BrainGate2 Neural Interface System in people with tetraplegia and related conditions; the t…