Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS trial_result · 2026-06-30Clinical Trial Results: Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial [Phase 1, Phase 2]
Results from a basket trial evaluating interventions across neurodegenerative diseases including amyotrophic lateral sclerosis and Alzheimer…
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CLINICAL_TRIALS trial_result · 2026-06-17Clinical Trial Results: Ph1 T-Regulatory Cells in Amyotrophic Lateral Sclerosis [Phase 1]
Phase 1 trial evaluating regulatory T cells in amyotrophic lateral sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Study in ALS With Abatacept & IL-2 [Phase 1]
Phase 1 study evaluating abatacept in combination with interleukin-2 in amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: A Mindful Community for People With ALS and Their Primary Caregivers [NA]
Harvard University-sponsored clinical trial titled 'A Mindful Community for People With ALS and Their Primary Caregivers' has completed. The…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Unrelated Umbilical Cord Blood Transplantation for the Treatment of Amyotrophic Lateral Sclerosis (ALS) [NA]
A clinical trial listing shows ongoing enrollment by invitation for unrelated umbilical cord blood transplantation as a treatment for amyotr…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Personalized Antisense Oligonucleotide Therapy for A Single Participant With TARDBP ALS [Phase 1, Phase 2]
A personalized antisense oligonucleotide therapy targeting TARDBP was tested in a single participant with amyotrophic lateral sclerosis in P…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
A Phase 2 clinical trial to evaluate the effects of VHB937 in people with amyotrophic lateral sclerosis is active but not currently recruiti…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Phase 2a Study of TPN-101 in Patients With C9ORF72 ALS/FTD [Phase 2]
Phase 2a study of TPN-101 in patients with C9ORF72-associated ALS/FTD has completed.
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Blood-Brain Barrier Opening Using MR-Guided Focused Ultrasound in Patients With Amyotrophic Lateral Sclerosis [NA]
This update reports the completion of a clinical trial evaluating MRI-guided focused ultrasound to transiently open the blood-brain barrier …
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Ambulatory Versus Inpatient Initiation of Home Mechanical Ventilation [NA]
This clinical trial update concerns a study comparing ambulatory versus inpatient initiation of home mechanical ventilation in amyotrophic l…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis [Phase 1]
This clinical trial is a Phase 1 study evaluating LY4256984 in adults with sporadic amyotrophic lateral sclerosis, and it is currently recru…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS [Phase 2, Phase 3]
Clinical trial update for ibudilast (MN-166) in amyotrophic lateral sclerosis, outlining a 12-month treatment period followed by a 6-month o…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Efficacy and Safety of Tazbentetol in ALS Participants [Phase 2, Phase 3]
The document reports a Phase 2/Phase 3 clinical trial evaluating the efficacy and safety of Tazbentetol for amyotrophic lateral sclerosis, w…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Focal Accumulation of Iron in Cerebral Regions in Early ALS (Amyotrophic Lateral Sclerosis) Patients [Phase 2]
Phase 2 trial evaluating focal iron accumulation in cerebral regions of early amyotrophic lateral sclerosis patients has completed, examinin…
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Implementing Spiritual Care in Inpatient Palliative Care
A completed clinical trial from University Hospital Muenster assesses implementing spiritual care in inpatient palliative care for patients …
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: RAPA-501 Therapy of ALS Expanded Access Protocol
This clinical trial update indicates that the expanded access protocol for RAPA-501 to treat amyotrophic lateral sclerosis is temporarily no…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Tofersen in Non-SOD1 ALS [Phase 2]
Phase 2 clinical trial of tofersen for non-SOD1 amyotrophic lateral sclerosis is currently recruiting, exploring safety and potential effica…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Satisfaction of Patients With Amyotrophic Lateral Sclerosis Regarding Home Assisted Teleconsultation [NA]
This clinical trial evaluating patient satisfaction with home-assisted teleconsultation for amyotrophic lateral sclerosis has been terminate…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: New Magnetic Resonance Imaging Biomarkers in Amyotrophic Lateral Sclerosis [NA]
Completed study investigating new MRI biomarkers for amyotrophic lateral sclerosis. The findings suggest potential imaging indicators for di…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Respiratory Muscle Training (RMT) in ALS [NA]
The clinical trial evaluating Respiratory Muscle Training (RMT) in amyotrophic lateral sclerosis has completed and posted results.
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: HEALEY ALS Platform Trial - Regimen G DNL343 [Phase 2, Phase 3]
Results from the HEALEY ALS Platform Trial Regimen G evaluating DNL343 in amyotrophic lateral sclerosis have been posted after completion of…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Atalante Exoskeleton in the Rehabilitation of Patients With Amyotrophic Lateral Sclerosis [NA]
A clinical trial update indicates the Atalante Exoskeleton study for rehabilitation in amyotrophic lateral sclerosis has been suspended.
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Spinal Interneuron Excitability in ALS [NA]
This clinical trial update notes that the study on spinal interneuron excitability in amyotrophic lateral sclerosis has completed. The snipp…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS. [NA]
The NO-ALS study, sponsored by Haukeland University Hospital, is evaluating a nicotinamide/pterostilbene supplement for amyotrophic lateral …
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial [Phase 1, Phase 2]
This clinical trial update reports that the NADALS basket trial, evaluating conditions including Alzheimer's disease, amyotrophic lateral sc…