Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS withdrawal · 2026-04-16Clinical Trial Update: Nebulized RNS60 for the Treatment of Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 trial evaluating nebulized RNS60 for Amyotrophic Lateral Sclerosis has been withdrawn from ClinicalTrials.gov.
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CLINICAL_TRIALS withdrawal · 2026-04-07Clinical Trial Update: Two Intermediate Expanded Access Protocols (EAP) CNMAu8.EAP01 and CNMAu8.EAP02 for ALS
Two intermediate Expanded Access Protocols for CNM-Au8 (CNMAu8.EAP01 and CNMAu8.EAP02) in amyotrophic lateral sclerosis are no longer availa…
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CLINICAL_TRIALS withdrawal · 2025-09-02Clinical Trial Update: Intermediate-Sized Expanded Access Study
An intermediate-sized expanded access study for amyotrophic lateral sclerosis sponsored by Seelos Therapeutics is no longer available.
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CLINICAL_TRIALS withdrawal · 2025-08-20Clinical Trial Update: IC14 for ALS Patients Expanded Access
The Expanded Access program for IC14 in Amyotrophic Lateral Sclerosis has ended and is no longer available.
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CLINICAL_TRIALS withdrawal · 2025-08-17Clinical Trial Update: IC14 for Treatment of Amyotrophic Lateral Sclerosis [Phase 2]
A Phase 2 clinical trial of IC14 for amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Study to Explore the Role of Gut Flora in ALS
This clinical trial evaluating the role of gut flora in amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders
The University of Massachusetts Worcester-sponsored genetic study on familial and sporadic amyotrophic lateral sclerosis/motor neuron diseas…
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EMA withdrawal · 2024-02-01EMA Refused: Albrioza (sodium phenylbutyrate;ursodoxicoltaurine) — Amylyx Pharmaceuticals EMEA B.V.
The EMA refused approval for Albrioza (sodium phenylbutyrate; ursodoxicoltaurine) for amyotrophic lateral sclerosis.
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EMA withdrawal · 2019-08-14EMA Application withdrawn: Radicava (edaravone) — Mitsubishi Tanabe Pharma GmbH
European Medicines Agency status update indicating withdrawal of the Radicava (edaravone) application by Mitsubishi Tanabe Pharma GmbH for a…
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EMA withdrawal · 2018-07-31EMA Refused: Alsitek (Masitinib mesilate) — AB Science
The EMA refused approval for Masitinib mesilate (Alsitek) for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS withdrawal · 2018-06-04Clinical Trial Update: Cervical Spinal Cord Metabolism and Microstructure in Amyotrophic Lateral Sclerosis(ALS) [NA]
The University of Michigan–sponsored clinical trial studying cervical spinal cord metabolism and microstructure in Amyotrophic Lateral Scler…
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CLINICAL_TRIALS withdrawal · 2017-10-11Clinical Trial Update: Involvement of Lymphocyte Type B in Amyotrophic Lateral Sclerosis (ALS)
A clinical trial investigating the involvement of B lymphocytes in amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-05-31Clinical Trial Update: Microglial Activation Role In ALS (MARIA) [EARLY_Phase 1]
The MARIA trial, an early phase 1 study examining microglial activation in amyotrophic lateral sclerosis, has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-02-07Clinical Trial Update: Incobotulinum Toxin A for Sialorrhea in Parkinson's Disease (PD)/Parkinsonism and Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
A Phase 2 trial of incobotulinum toxin A for sialorrhea in Parkinson disease and amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-01-14Clinical Trial Update: Mesenchymal Stem Cell Injection in Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
Phase 1/2 trial of mesenchymal stem cell injections for amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-01-01Clinical Trial Update: Intraventricular Transplantation of Mesenchymal Stem Cell in Patients With ALS [Phase 1]
A phase 1 trial evaluating intraventricular transplantation of mesenchymal stem cells in patients with amyotrophic lateral sclerosis was wit…
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CLINICAL_TRIALS withdrawal · 2015-09-01Clinical Trial Update: Magnetic Resonance Imaging (MRI) in Amyotrophic Lateral Sclerosis (ALS) [NA]
A Johns Hopkins University-sponsored MRI study in amyotrophic lateral sclerosis has been withdrawn, with no active recruitment or results ex…
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CLINICAL_TRIALS withdrawal · 2014-11-10Clinical Trial Update: Coping Effectiveness Training for ALS [NA]
A clinical trial evaluating Coping Effectiveness Training for Amyotrophic Lateral Sclerosis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2012-02-09Clinical Trial Update: A Multicenter, Double-Blind Study to Investigate the Safety and Efficacy of Arimoclomol in Volunteers With ALS [Phase 2]
A Phase 2 double-blind study of Arimoclomol for amyotrophic lateral sclerosis has been withdrawn.