Amyotrophic Lateral Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of FHND1002 Granules in Healthy Adults [Phase 1]
Phase 1 clinical trial update for FHND1002 Granules assessing safety, tolerability, and pharmacokinetics in healthy adults, with amyotrophic…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: A First in Human Study of ORT247 in Healthy Volunteers [Phase 1]
First-in-human Phase 1 trial of ORT247 in healthy volunteers has completed, evaluating initial safety, tolerability, and pharmacokinetics.
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Extension Study Evaluating The Safety And Tolerability of AMX0035 [Phase 3]
This document reports the completion of a Phase 3 extension study evaluating the safety and tolerability of AMX0035 in amyotrophic lateral s…
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications [NA]
A Penn State University clinical trial is currently recruiting to evaluate verbal communication in structured interactions for individuals w…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: Evaluation the Efficacy and Safety of Mutiple Lenzumestrocel (Neuronata-R® Inj.) Treatment in Patients with ALS [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of multiple Lenzumestrocel (Neuronata-R) injections in patients with amyotrophic l…
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CLINICAL_TRIALS trial_result · 2025-01-10Clinical Trial Update: A Follow up Study to Protocol 101/2 - Continued Treatment by IPL344 IV [Phase 2]
The Phase 2 follow-up study of IPL344 IV for amyotrophic lateral sclerosis has been suspended.
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CLINICAL_TRIALS other · 2025-01-10Clinical Trial Update: A Study of IPL344 in the Treatment of ALS Patients [Phase 1, Phase 2]
This clinical trial update indicates that IPL344 for amyotrophic lateral sclerosis is in Phase 1/Phase 2 but has been suspended. The sponsor…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Clinical Study of Induced Pluripotent Stem Cells Derived Motor Neuron Precursor Cell Therapy for Amyotrophic Lateral Sclerosis (ALS) [NA]
A recruiting clinical trial is evaluating an induced pluripotent stem cell–derived motor neuron precursor cell therapy for amyotrophic later…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Genetic Study of Amyotrophic Lateral Sclerosis in Norway
A genetic study of amyotrophic lateral sclerosis in Norway is currently recruiting participants, sponsored by Sykehuset Telemark.
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RAG-17 in Subjects With Amyotrophic Lateral Sclerosis (ALS) With Superoxide Dismutase Type 1 (SOD1) Gene Mutation [Phase 1]
Phase 1 clinical trial evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of RAG-17 in Amyotrophic Lateral Sclerosis pa…
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CLINICAL_TRIALS other · 2025-01-08Clinical Trial Update: Breathing with Amyotrophic Lateral Sclerosis [NA]
A recruiting clinical trial in amyotrophic lateral sclerosis titled 'Breathing with Amyotrophic Lateral Sclerosis' is being conducted at Uni…
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Study of ANX005 in Adults With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 study of ANX005 in adults with amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: A Study to Assess the Effect of Erythromycin on the Test Medicine (SAR443820) When Given Orally as Tablets to Healthy Adult Male and Female Participants (Part A); and the Effect of Itraconazole on the Test Medicine (SAR443820) When Given Orally as Capsules to Healthy Adult Male Participants (Part B) [Phase 1]
This Phase 1 study evaluated the effect of erythromycin (Part A) and itraconazole (Part B) on SAR443820 pharmacokinetics when taken orally i…
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FDA approval · 2024-12-23FDA Approved: EDARAVONE — Original Application (Sandoz Inc)
FDA approved a generic edaravone product from Sandoz Inc under an original application for the treatment of amyotrophic lateral sclerosis.
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: TP04HN106 in the Treatment of Patients With Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
A clinical trial update for TP04HN106 in amyotrophic lateral sclerosis, a Phase 1/Phase 2 study that is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZYIL1 in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
This clinical trial update summarizes Phase 2 results for ZYIL1 in amyotrophic lateral sclerosis, including efficacy, safety, tolerability, …
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
A clinical trial update reports completion of a genetics study on pediatric-onset motor neuron and neuromuscular diseases, including spinal …
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP [NA]
A National Taiwan University Hospital-sponsored clinical trial is recruiting to evaluate plasmapheresis in amyotrophic lateral sclerosis pat…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Proteinopathies Expression in Skin of Neurodegenerative Disorders
Clinical trial examining skin expression of proteinopathies in several neurodegenerative diseases; currently recruiting and led by Universid…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Safety and Efficacy of Ranolazine for the Treatment of Amyotrophic Lateral Sclerosis [Phase 2]
This document reports Phase 2 trial results for ranolazine in amyotrophic lateral sclerosis, focusing on safety and efficacy, with the study…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Ultra-high-caloric, Fatty Diet in ALS [NA]
A clinical trial at the University of Ulm is evaluating an ultra-high-caloric, fatty diet in people with amyotrophic lateral sclerosis and i…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 3]
Phase 3 study of Reldesemtiv in amyotrophic lateral sclerosis was terminated; results have been posted.
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418 [Phase 1]
Phase 1 study update for FB418 evaluating safety and tolerability in Parkinson disease and ALS; currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Geometrical Facial Deformation According to Posture in Amyotrophic Lateral Sclerosis
This clinical trial update reports results on geometrical facial deformation according to posture in Amyotrophic Lateral Sclerosis, with res…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Anticipated Patient and Caregiver Burden [NA]
A clinical trial update notes ongoing recruitment for an ALS study and discusses anticipated burden on patients and caregivers.