Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis [NA]
This clinical trial update describes a French-German cohort study investigating factors associated with weight loss in amyotrophic lateral s…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Tofacitinib in Patients With Amyotrophic Lateral Sclerosis [EARLY_Phase 1]
An early-phase 1 clinical trial is investigating tofacitinib in patients with amyotrophic lateral sclerosis, with the study currently not ye…
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases
FLOWER is a longitudinal epidemiology study by xCures to follow outcomes across multiple rare diseases, and the study is currently recruitin…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Home-based Remote Digital Monitoring to Assess ALS Progression (Track ALS)
The Track ALS study, a home-based remote digital monitoring trial to assess ALS progression, has completed. Sponsor: St. Joseph's Hospital a…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Polish Version Fatigue Severity Scale
A Polish-version Fatigue Severity Scale trial is currently recruiting, sponsored by Jakub Antczak, involving patients with multiple sclerosi…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Testing Pulse Stimulation to Improve Motor Function in People With ALS: A Pilot Study [NA]
Clinical trial update for a pilot study testing pulse stimulation to improve motor function in people with amyotrophic lateral sclerosis; re…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Evaluate the Safety of Neuronata-R® Inj. Suspended With HypoTHermosol® FRS (HTS-FRS) in Patients With ALS [Phase 1]
A Phase 1 trial assessing the safety of Neuronata-R with HypoTHermosol FRS in amyotrophic lateral sclerosis has been suspended; no results a…
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: Quest to Analyze One Thousand Humans Meditating
A ClinicalTrials.gov update indicates a study is enrolling up to 1,000 participants to assess the effects of meditation across multiple cond…
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FDA approval · 2024-10-31FDA Approved: EDARAVONE — Original Application (XGen Pharmaceuticals DJB, Inc.)
The FDA approved the Original Application for edaravone from XGen Pharmaceuticals DJB, Inc., enabling a generic version of the ALS therapy t…
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CLINICAL_TRIALS research · 2024-10-31Clinical Trial Update: Exploring Nasal Drop Therapy With Small Extracellular Vesicles for ALS [Phase 1, Phase 2]
Ongoing clinical trial assessing nasal drop therapy using small extracellular vesicles for amyotrophic lateral sclerosis; currently recruiti…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: A Prospective Study to Evaluate the Correlation Between Oculometric Measurements and Clinical Endpoints in ALS Patients
A completed prospective study evaluating whether oculometric measurements correlate with clinical endpoints in patients with amyotrophic lat…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Validation Study
A completed validation study evaluating the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) for detecting cognitive impairment in Norw…
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Prospective Cohort Study
It provides an update on a prospective cohort study evaluating the Edinburgh Cognitive and Behavioural ALS Screen in Norway. The study relat…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Virtual Peer-to-peer Support Programme for Carers of MND [NA]
A clinical trial update announcing a virtual peer-to-peer support program for carers of people with motor neuron disease/amyotrophic lateral…
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients [NA]
A clinical trial is recruiting to evaluate the effects of probiotics in patients within the amyotrophic lateral sclerosis-frontotemporal dem…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: An IIT Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of a Single Intrathecal Injection of SNUG01 in Patients with Amyotrophic Lateral Sclerosis [EARLY_Phase 1]
An IIT Phase 1 study to evaluate the safety, tolerability, and preliminary efficacy of a single intrathecal injection of SNUG01 in patients …
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Dysphagia, QoL and Attitudes Towards PEG in ALS Patients
Clinical trial update for ALS examining dysphagia, quality of life, and attitudes toward PEG; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Contralateral R1 in Amyotrophic Lateral Sclerosis
A clinical trial evaluating Contralateral R1 for Amyotrophic Lateral Sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Study of [11C]CPPC to Assess the Safety and Tolerability in Patients With ALS [Phase 1]
A Phase 1 trial evaluating the safety and tolerability of the PET tracer [11C]CPPC in patients with amyotrophic lateral sclerosis has been t…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: A Biomarker Study to Evaluate MN-166 in Subjects With Amyotrophic Literal Sclerosis (ALS) [Phase 1, Phase 2]
A Phase 1/2 biomarker study evaluating MN-166 (ibudilast) in Amyotrophic Lateral Sclerosis has completed enrollment and posted results.
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Retrospective Study on the Safety and Therapeutic/Improvement Effects of Intravenous Administration of SHED-CM for ALS (SHED-CAH2023)
A completed retrospective study assessing the safety and potential therapeutic effects of intravenous SHED-CM in amyotrophic lateral scleros…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Influence of Olfacto-gustatory Sensoriality on the Nutritional Status of Patients with Amyotrophic Lateral Sclerosis
A clinical trial evaluating the influence of olfactory and gustatory sensory changes on nutritional status in patients with amyotrophic late…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Rapamycin Treatment for ALS [Phase 2]
A Phase 2 trial evaluating rapamycin for amyotrophic lateral sclerosis has completed. The snippet does not include trial results.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis [Phase 1]
A Phase 1 study evaluating the safety, pharmacokinetics, and pharmacodynamics of DNL343 in individuals with Amyotrophic Lateral Sclerosis ha…
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: Quantitative and Repetitive TMS in ALS - Recruiting for Stage 2 [NA]
Stage 2 recruitment is ongoing for a study using quantitative and repetitive transcranial magnetic stimulation in amyotrophic lateral sclero…