Gastroesophageal Junction Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Comparing the Efficacy and Safety of Different Postoperative Adjuvant Regimens in Patients With Resectable Adenocarcinoma of the Esophagogastric Junction Who Underwent Radical Surgery After Neoadjuvant Chemotherapy Combined With Immunotherapy and Achieved pCR in Postoperative Pathology [Phase 4]
Phase 4 trial evaluating different postoperative adjuvant regimens after radical surgery for resectable gastric or gastroesophageal junction…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 clinical trial update evaluating chemoradiation with pembrolizumab, followed by pembrolizumab and lenvatinib before surgery for no…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Immunotherapy Combined With Anti-angiogenic Therapy and Chemotherapy for Potentially Resectable MSI-H, dMMR Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]
A Phase 2 clinical trial is evaluating a combination of immunotherapy, anti-angiogenic therapy, and chemotherapy in MSI-H/dMMR locally advan…
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FDA approval · 2025-08-21FDA Approved: TRAZIMERA — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for TRAZIMERA (trastuzumab-qyyp) from Pfizer Laboratories Div Pfizer Inc, authorizing changes under …
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of Treatment Patterns in HER2-positive Unresectable and Advanced Gastric/ Gastroesophageal Junction Cancer in China
Completed clinical trial in China evaluating treatment patterns for patients with HER2-positive unresectable or advanced gastric cancer and …
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer [Phase 2]
Phase 2 trial update examining zimberelimab with or without domvanalimab in resectable MSI-H/dMMR gastric and gastroesophageal junction canc…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Clinical Study of SHR-1701 Plus Chemotherapy as Perioperative Treatment in Subjects With Gastric Cancer [Phase 2, Phase 3]
A Phase 2/3 trial of SHR-1701 plus chemotherapy as perioperative treatment for locally advanced resectable gastric cancer or gastroesophagea…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Comparing the Efficacy and Safety of Chemotherapy Combined With or Without Immunotherapy as an Adjuvant Treatment After Radical Surgery for Patients With Resectable Adenocarcinoma of the Esophagogastric Junction of Gastric Cancer [Phase 4]
A Phase 4 clinical trial update evaluating adjuvant chemotherapy with or without immunotherapy after radical surgery for resectable gastric …
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Study of BL-M07D1 Combination Therapy in Patients With Unresectable Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating BL-M07D1 in combination therapy for unresectable locally advanced or metastatic HER2-positive gastric or g…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Efficacy and Safety of AK112 Combined Chemotherapy as Neoadjuvant Treatment for Signet Ring Cell-containing G/GEJ Adenocarcinoma [Phase 2]
A Phase 2 trial is evaluating AK112 in combination with chemotherapy as neoadjuvant therapy for signet ring cell-containing gastric or gastr…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Pucotenlimab Combined With Chemotherapy as Perioperative Treatment for Locally Advanced Gastroesophageal Junction Carcinoma [NA]
Clinical trial update shows pucotenlimab with chemotherapy is being studied as perioperative therapy for locally advanced gastroesophageal j…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: HER2-positive Locally Advanced/Metastatic Gastric and/or Gastroesophageal Junction (GEJ) Adenocarcinoma in Russia
AstraZeneca's clinical trial in Russia evaluating HER2-positive gastric and gastroesophageal junction adenocarcinoma has completed (NCT05892…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Perioperative Tislelizumab Plus Chemotherapy Versus Chemotherapy Alone in MHC-II-Positive Gastric/GEJ Cancer [Phase 3]
A Phase 3 trial is investigating perioperative tislelizumab plus chemotherapy versus chemotherapy alone for MHC-II-positive gastric/GEJ canc…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: T-Dxd in Combination With Ramucirumab as HER2 Low Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating trastuzumab deruxtecan in combination with ramucirumab for HER2-low gastric or gastroesophageal juncti…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of pembrolizumab and olaparib for recurrent/advanced gastric cancer and gastroesophage…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Tislelizumab Combined With Anlotinib and Chemotherapy (XELOX) in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (TALENT) [Phase 1, Phase 2]
A Phase 1/2 study (TALENT) evaluated tislelizumab with anlotinib and XELOX chemotherapy for advanced gastric or gastroesophageal junction ad…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: A Clinical Trail of KJ015 in Patients With HER2-Expressing Solid Tumors [Phase 1]
A Phase 1 trial update for KJ015 in HER2-expressing solid tumors shows the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-18Clinical Trial Update: Preoperative HFRT Verses PULSAR for Locally Advanced GEJ or Proximal Gastric Adenocarcinoma [Phase 2]
A Phase 2 trial comparing preoperative hypofractionated radiotherapy (HFRT) versus the PULSAR approach for locally advanced gastroesophageal…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Efficacy and Safety Study of Multiple Doses of IMAB362 in Patients With Advanced Gastroesophageal Cancer [Phase 2]
Phase 2 study evaluating efficacy and safety of multiple doses of IMAB362 in patients with advanced gastroesophageal cancer. The trial statu…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: TremelImumab aNd Durvalumab For the Non-operatIve Management (NOM) of MSI-high Resectable GC/GEJC. [Phase 2]
A Phase 2 study testing tremelimumab plus durvalumab for non-operative management of MSI-high resectable gastric cancer and gastroesophageal…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: TAC T-cells for the Treatment of HER2-positive Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating TAC T-cells for HER2-positive solid tumors, including HER2-positive gastric cancer and metastatic HER2-positive g…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Neoadjuvant Capecitabine, Oxaliplatin, Docetaxel and Atezolizumab in Resectable Gastric and GE-junction Cancer (PANDA) [Phase 2]
Phase 2 neoadjuvant trial PANDA investigates a four-drug regimen (capecitabine, oxaliplatin, docetaxel, and atezolizumab) for resectable gas…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Robotic Versus Laparoscopic Radical Surgery for Locally Advanced Gastric Cancer [NA]
A clinical trial comparing robotic versus laparoscopic radical surgery for locally advanced gastric cancer is currently recruiting in China.
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Ivonescimab (AK112) Plus Paclitaxel as Second-line Therapy in Patients With Advanced G/GEJ Cancer [Phase 2]
Phase 2 trial update for Ivonescimab (AK112) plus paclitaxel as second-line therapy in advanced gastric/gastroesophageal junction cancer; th…
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: Retrospective Evaluation of Nivolumab in Adjuvant Esophageal Cancer/Gastroesophageal Junction Cancer
This clinical trial update summarizes a retrospective evaluation of nivolumab as adjuvant therapy for esophageal cancer and gastroesophageal…