Gastroesophageal Junction Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: IKS014 in Advanced Solid Tumors That Express HER2 [Phase 1]
Phase 1 clinical trial of IKS014 for HER2-expressing advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS other · 2026-01-09Clinical Trial Update: A Trial of Adebrelimab Plus (SHR-A1811/SHR-A1904 With Chemotherapy) or SHR-8068 as Treatment for Gastric/GEJ Cancer [Phase 2]
Phase 2 clinical trial update on Adebrelimab plus SHR-A1811/SHR-A1904 with chemotherapy or SHR-8068 for gastric and gastroesophageal junctio…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Trastuzumab Deruxtecan to Treat HER2 + Newly Diagnosed Metastatic GI Cancers [Phase 2]
Phase 2 trial update evaluating trastuzumab deruxtecan for HER2-positive newly diagnosed metastatic esophageal, gastric, and gastroesophagea…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Factors Influencing Immunotherapy Response in dMMR/MSI-H Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 2]
A Phase 2 clinical trial is exploring factors that influence immunotherapy response in mismatch repair-deficient or MSI-H gastric and gastro…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Iparomlimab and Tuvonralimab (QL1706) Combined With Chemotherapy for Previously Untreated Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer [Phase 2]
A Phase 2 trial evaluating the combination of Iparomlimab and Tuvonralimab (QL1706) with chemotherapy in previously untreated advanced or me…
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CLINICAL_TRIALS trial_result · 2025-12-30Clinical Trial Update: [68Ga]Ga-FAPI PET/CT in Gastric and Gastroesophageal Junctional Cancer [Phase 2]
The clinical trial update reports the completion of a Phase 2 study evaluating [68Ga]Ga-FAPI PET/CT imaging in gastric cancer and gastroesop…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer [Phase 3]
A Phase 3 trial evaluating the combination of durvalumab with the FLOT chemotherapy regimen in resectable gastric and gastroesophageal junct…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis [Phase 1]
This is a Phase 1 clinical trial evaluating Aldesleukin in combination with Nivolumab and standard chemotherapy for clinical stage IV gastri…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
Ongoing Stanford University clinical trial evaluating clinical and pathological aspects of upper gastrointestinal cancers, including stomach…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma [Phase 3]
This clinical trial update describes a Phase 3 study evaluating a triplet regimen of Osemitamab (TST001), pembrolizumab, and chemotherapy as…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Clinical trial update for TST001 in advanced or metastatic solid tumors (Phase 1/2); the study is currently active and not recruiting.
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma [Phase 1]
Phase 1 clinical trial evaluating Claudin 18.2-targeted CAR-T cells in unresectable/locally advanced or metastatic gastric, gastroesophageal…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: A Study Evaluating Bemarituzumab in Combination With Other Anti-cancer Therapies in Subjects With Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer. [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial update on bemarituzumab in combination with other anti-cancer therapies for previously untreated advanced gas…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: A Study to Evaluate Nivolumab in Patients With Unresectable Advanced/Metastatic Gastric Cancer and Gastroesophageal Junction Cancer
A completed clinical trial evaluating nivolumab in patients with unresectable, advanced or metastatic gastric cancer and gastroesophageal ju…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: The Efficacy and Safety of Laparoscopic Proximal Gastrectomy With LPG-tbROSF Versus LTG for Localized Proximal Gastric Cancer. [NA]
This clinical trial assesses the efficacy and safety of laparoscopic proximal gastrectomy with LPG-tbROSF versus laparoscopic total gastrect…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer [Phase 2]
Phase 2 clinical trial update reporting ongoing recruitment for a combination therapy (agenT-797 with Botensilimab, Balstilimab, Ramucirumab…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: Tislelizumab Combined With XELOX as Neoadjuvant Therapy for G/GEJ Adenocarcinoma [Phase 2]
Phase 2 trial evaluating tislelizumab combined with XELOX as neoadjuvant therapy for locally advanced gastric or gastroesophageal junction a…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Utidelone Capsule Combined With Fluoropyrimidine- and Platinum-containing Therapy in First-line Treatment of Patients With Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating Utidelone capsules in combination with fluoropyrimidine- and platinum-containing therapy as first-line…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study) [Phase 1, Phase 2]
Spevatamig (PT886) is being studied as a monotherapy or in combination with chemotherapy and/or immune checkpoint inhibitors in Phase 1/2 tr…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers [Phase 1]
A Phase 1 study of AMG 199 in MUC17-positive solid tumors including gastric, gastroesophageal junction, colorectal, and pancreatic cancers h…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: A Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer [Phase 1, Phase 2]
Clinical trial update on AZD7789 evaluating safety and efficacy in participants with advanced or metastatic solid cancers in Phase 1/2.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: A Clinical Study To Evaluate Camrelizumab (SHR-1210) Plus Capecitabine and Oxaliplatin Followed by Sequential Treatment With Camrelizumab Plus Apatinib Mesylate in Advanced or Metastatic Gastric Cancer (GC) or Gastroesophageal Junction Cancer (GEJ) Without Prior Systemic Therapy [Phase 3]
Phase 3 trial evaluating camrelizumab with capecitabine and oxaliplatin, followed by camrelizumab with apatinib, in advanced/metastatic gast…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: ASKB589 in Combination With CAPOX and PD-1 Inhibitors in Patients With Advanced, and Unresectable G/GEJ Cancer. [Phase 1, Phase 2]
The document summarizes a Phase 1/Phase 2 clinical trial evaluating ASKB589 in combination with CAPOX chemotherapy and PD-1 inhibitors for p…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Neoadjuvant Radiotherapy Plus Tegafur, Oxaliplatin and Iparomlimab and Tuvonralimab in Resectable Gastric and GE-junction Cancer : A Randomized, Two-arm, Prospective Trial (TRIUNITE-05) [Phase 2]
Phase 2 randomized trial evaluating neoadjuvant radiotherapy plus tegafur, oxaliplatin, iparomlimab, and tuvonralimab in resectable gastric …
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Study of NX-1607 in Adults With Advanced Malignancies [Phase 1]
A Phase 1 study evaluating NX-1607 in adults with advanced malignancies is actively recruiting across multiple tumor types, including ovaria…