Gastroesophageal Junction Cancer

CLINICAL_TRIALS trial_result · 2026-07-30

Clinical Trial Results: Study of Oxaliplatin and Xeloda and Cetuximab as First Line Treatment for Metastatic or Unresectable Gastric or Gastroesophageal Junction Cancer [Phase 2]

Phase 2 trial evaluating a combination of oxaliplatin, Xeloda (capecitabine), and cetuximab for first-line treatment of metastatic or unrese…

CLINICAL_TRIALS trial_result · 2026-04-17

Clinical Trial Update: A Phase 1b/2 Clinical Trial Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AUR103 Calcium in Patients With HER2-positive Advanced Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 1, Phase 2]

Phase 1b/2 trial of AUR103 calcium in HER2-positive advanced gastric cancer and gastroesophageal junction adenocarcinoma has been terminated…

CLINICAL_TRIALS trial_result · 2026-04-15

Clinical Trial Update: An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junction Carcinoma [Phase 1, Phase 2]

This Roche umbrella Phase 1/2 trial evaluating multiple treatment combinations in gastric and gastroesophageal junction carcinoma was termin…

CLINICAL_TRIALS trial_result · 2026-04-13

Clinical Trial Update: Clinical Study of Adebrelimab Therapy in the Perioperative Treatment of Gastric Cancer or Gastroesophageal Junction Cancer [Phase 3]

A Phase 3 clinical trial evaluating Adebrelimab as perioperative therapy for locally advanced gastric or gastroesophageal junction cancer is…

CLINICAL_TRIALS trial_result · 2026-04-03

Clinical Trial Update: A Study of Trastuzumab in Combination With Capecitabine and Cisplatin in Patients With Tissue HER2- But Serum HER2+ AGC [Phase 2]

A Phase 2 trial evaluating trastuzumab in combination with capecitabine and cisplatin in patients with tissue HER2-negative but serum HER2-p…

CLINICAL_TRIALS trial_result · 2026-03-19

Clinical Trial Update: Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients [Phase 1]

Phase 1 trial of Cabotamig (ARB202) in advanced gastrointestinal cancers has completed; no specific efficacy results are provided in the doc…

CLINICAL_TRIALS trial_result · 2026-03-18

Clinical Trial Update: PReoperative Chemoradiation (Paclitaxel-carboplatin or FOLFOX) for Resectable Esophageal and Junctional Cancer [Phase 2]

A Phase 2 study evaluating preoperative chemoradiation with either paclitaxel-carboplatin or FOLFOX for resectable esophageal and gastroesop…

CLINICAL_TRIALS trial_result · 2026-03-10

Clinical Trial Update: Concentrated Complex Plant Dietary Elements for Chemotherapy-Induced Diarrhea [Phase 2]

Phase 2 trial evaluating concentrated complex plant dietary elements to prevent chemotherapy-induced diarrhea in patients with gastric, gast…

CLINICAL_TRIALS trial_result · 2026-02-23

Clinical Trial Update: A Study of Total Neoadjuvant Chemotherapy With FLOT VS Standard Perioperative FLOT in Patients With Gastric or GEJ Cancer [Phase 2]

Phase 2 trial comparing total neoadjuvant chemotherapy with the FLOT regimen versus standard perioperative FLOT in gastric and gastroesophag…

CLINICAL_TRIALS trial_result · 2026-02-19

Clinical Trial Update: PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors [Phase 1]

Phase 1 clinical trial update for PF-07265028 as a single agent and in combination with sasanlimab in advanced/metastatic solid tumors has b…

CLINICAL_TRIALS trial_result · 2026-02-04

Clinical Trial Update: Clinical Study on the Efficacy and Safety of LM-302 Injection Combined With Tislelizumab and Tislelizumab Combined Chemotherapy for the Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma. [Phase 3]

Phase 3 clinical study evaluating LM-302 in combination with tislelizumab, and tislelizumab-based chemotherapy, for gastric or gastroesophag…

CLINICAL_TRIALS trial_result · 2026-02-02

Clinical Trial Update: A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation [Phase 1]

A Phase 1 study of PRT7732, an oral SMARCA2 degrader, in patients with SMARCA4-mutant advanced or metastatic solid tumors has been terminate…

CLINICAL_TRIALS trial_result · 2026-01-15

Clinical Trial Update: IKS014 in Advanced Solid Tumors That Express HER2 [Phase 1]

Phase 1 clinical trial of IKS014 for HER2-expressing advanced solid tumors is currently recruiting.

CLINICAL_TRIALS trial_result · 2025-12-30

Clinical Trial Update: [68Ga]Ga-FAPI PET/CT in Gastric and Gastroesophageal Junctional Cancer [Phase 2]

The clinical trial update reports the completion of a Phase 2 study evaluating [68Ga]Ga-FAPI PET/CT imaging in gastric cancer and gastroesop…

CLINICAL_TRIALS trial_result · 2025-12-04

Clinical Trial Update: A Study to Evaluate Nivolumab in Patients With Unresectable Advanced/Metastatic Gastric Cancer and Gastroesophageal Junction Cancer

A completed clinical trial evaluating nivolumab in patients with unresectable, advanced or metastatic gastric cancer and gastroesophageal ju…

CLINICAL_TRIALS trial_result · 2025-11-28

Clinical Trial Update: Tislelizumab Combined With XELOX as Neoadjuvant Therapy for G/GEJ Adenocarcinoma [Phase 2]

Phase 2 trial evaluating tislelizumab combined with XELOX as neoadjuvant therapy for locally advanced gastric or gastroesophageal junction a…

CLINICAL_TRIALS trial_result · 2025-10-14

Clinical Trial Update: Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers [Phase 1]

A Phase 1 study of AMG 199 in MUC17-positive solid tumors including gastric, gastroesophageal junction, colorectal, and pancreatic cancers h…

CLINICAL_TRIALS trial_result · 2025-09-08

Clinical Trial Update: Comparing the Efficacy and Safety of Different Postoperative Adjuvant Regimens in Patients With Resectable Adenocarcinoma of the Esophagogastric Junction Who Underwent Radical Surgery After Neoadjuvant Chemotherapy Combined With Immunotherapy and Achieved pCR in Postoperative Pathology [Phase 4]

Phase 4 trial evaluating different postoperative adjuvant regimens after radical surgery for resectable gastric or gastroesophageal junction…

CLINICAL_TRIALS trial_result · 2025-08-21

Clinical Trial Update: A Study of Treatment Patterns in HER2-positive Unresectable and Advanced Gastric/ Gastroesophageal Junction Cancer in China

Completed clinical trial in China evaluating treatment patterns for patients with HER2-positive unresectable or advanced gastric cancer and …

CLINICAL_TRIALS trial_result · 2025-08-20

Clinical Trial Update: Clinical Study of SHR-1701 Plus Chemotherapy as Perioperative Treatment in Subjects With Gastric Cancer [Phase 2, Phase 3]

A Phase 2/3 trial of SHR-1701 plus chemotherapy as perioperative treatment for locally advanced resectable gastric cancer or gastroesophagea…

CLINICAL_TRIALS trial_result · 2025-07-20

Clinical Trial Update: HER2-positive Locally Advanced/Metastatic Gastric and/or Gastroesophageal Junction (GEJ) Adenocarcinoma in Russia

AstraZeneca's clinical trial in Russia evaluating HER2-positive gastric and gastroesophageal junction adenocarcinoma has completed (NCT05892…

CLINICAL_TRIALS trial_result · 2025-06-26

Clinical Trial Update: Tislelizumab Combined With Anlotinib and Chemotherapy (XELOX) in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (TALENT) [Phase 1, Phase 2]

A Phase 1/2 study (TALENT) evaluated tislelizumab with anlotinib and XELOX chemotherapy for advanced gastric or gastroesophageal junction ad…

CLINICAL_TRIALS trial_result · 2025-06-18

Clinical Trial Update: Preoperative HFRT Verses PULSAR for Locally Advanced GEJ or Proximal Gastric Adenocarcinoma [Phase 2]

A Phase 2 trial comparing preoperative hypofractionated radiotherapy (HFRT) versus the PULSAR approach for locally advanced gastroesophageal…

CLINICAL_TRIALS trial_result · 2025-06-13

Clinical Trial Update: Efficacy and Safety Study of Multiple Doses of IMAB362 in Patients With Advanced Gastroesophageal Cancer [Phase 2]

Phase 2 study evaluating efficacy and safety of multiple doses of IMAB362 in patients with advanced gastroesophageal cancer. The trial statu…

CLINICAL_TRIALS trial_result · 2025-06-08

Clinical Trial Update: TAC T-cells for the Treatment of HER2-positive Solid Tumors [Phase 1, Phase 2]

Phase 1/2 trial evaluating TAC T-cells for HER2-positive solid tumors, including HER2-positive gastric cancer and metastatic HER2-positive g…

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