Gastroesophageal Junction Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study to Investigate the Effects of AZD0901 Monotherapy in Adult Participants With 2L+ Advanced or Metastatic Gastric or GEJ Adenocarcinoma Expressing CLDN18.2 [Phase 2]
Phase 2 trial evaluating AZD0901 as monotherapy in adults with 2L+ advanced or metastatic gastric or GEJ adenocarcinoma expressing CLDN18.2.…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer [Phase 3]
A Phase 3 clinical trial is evaluating a first-line combination of trastuzumab deruxtecan (TDXd), chemotherapy, pembrolizumab, and trastuzum…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Disitamab Vedotin Combined With SOX Regimen Versus SOX Alone as Adjuvant Therapy for HER2-Moderate/High Expressing Stage Ⅲ Gastric Cancer: A Prospective, Multicenter, Randomized, Phase Ⅱ Clinical Trial [Phase 2]
A Phase II randomized trial is evaluating disitamab vedotin plus the SOX chemotherapy regimen versus SOX alone as adjuvant therapy in HER2-e…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer.
A clinical trial update showing a safety study of zolbetuximab (VYLOY) in South Korea for gastric and gastroesophageal junction cancers, cur…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Concentrated Complex Plant Dietary Elements for Chemotherapy-Induced Diarrhea [Phase 2]
Phase 2 trial evaluating concentrated complex plant dietary elements to prevent chemotherapy-induced diarrhea in patients with gastric, gast…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2 [Phase 3]
Phase 3 trial comparing AZD0901 to investigator's choice of therapy in second- or later-line advanced or metastatic gastric or gastroesophag…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating TJ033721 (Givastomig) in adults with advanced or metastatic solid tumors; the study is currently recruiting and inc…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer [Phase 3]
Phase 3 clinical trial evaluating HLX22 in combination with trastuzumab and chemotherapy for gastroesophageal junction and gastric cancer, c…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Individually Tailored, Supervised, Remote Exercise Intervention to Improve Physical Function for Stage I-III Gastroesophageal Cancer Survivors, PRECISE Trial [NA]
The PRECISE trial is investigating a tailored, supervised, remote exercise program to improve physical function in Stage I-III gastroesophag…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of AZD5863 in adults with advanced or metastatic solid tumors is currently recruiting, including gastric cancer, gastroeso…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: A Study of Total Neoadjuvant Chemotherapy With FLOT VS Standard Perioperative FLOT in Patients With Gastric or GEJ Cancer [Phase 2]
Phase 2 trial comparing total neoadjuvant chemotherapy with the FLOT regimen versus standard perioperative FLOT in gastric and gastroesophag…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update for PF-07265028 as a single agent and in combination with sasanlimab in advanced/metastatic solid tumors has b…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Totally Versus Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer [NA]
A clinical trial comparing totally minimally invasive versus hybrid minimally invasive esophagectomy for resectable esophageal or gastroesop…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2 [Phase 2]
Phase 2 clinical trial evaluating AZD0901 in advanced solid tumours expressing Claudin18.2 is currently recruiting, including gastric cancer…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Phase III Study of SHR-A1811 in Combination With Chemotherapy and Adebrelimab in Previously Untreated Patients With Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 3]
A Phase III trial evaluating SHR-A1811 with chemotherapy and Adebrelimab in untreated, unresectable or metastatic gastric or gastroesophagea…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: First-line Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma With Dual Immunotherapy Combined With Chemotherapy [Phase 2]
A Phase 2 trial evaluating first-line dual immunotherapy plus chemotherapy for gastric or gastroesophageal junction adenocarcinoma; the stud…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca [Phase 1, Phase 2]
An ongoing Phase 1/2 study of abemaciclib plus ramucirumab for metastatic esophageal adenocarcinoma and metastatic gastroesophageal junction…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Albumin-bound Paclitaxel-based Second-line Treatment Regimens for Locally Advanced or Metastatic G/GEJ Adenocarcinoma
This clinical trial update reports ongoing recruitment for second-line regimens based on albumin-bound paclitaxel to treat locally advanced …
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Clinical Study on the Efficacy and Safety of LM-302 Injection Combined With Tislelizumab and Tislelizumab Combined Chemotherapy for the Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma. [Phase 3]
Phase 3 clinical study evaluating LM-302 in combination with tislelizumab, and tislelizumab-based chemotherapy, for gastric or gastroesophag…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers
This multicenter clinical trial compares minimally invasive proximal gastrectomy with total gastrectomy for proximal gastric and gastroesoph…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation [Phase 1]
A Phase 1 study of PRT7732, an oral SMARCA2 degrader, in patients with SMARCA4-mutant advanced or metastatic solid tumors has been terminate…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update indicates that TH9619 is being studied in a Phase 1/2 trial for advanced solid tumors, with recruitment ongoing a…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Study to Assess the Effect of OCT-598 in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating OCT-598 in patients with advanced solid tumors; the study is currently recruiting and includes multiple tu…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Clinical Efficacy of Pucotenlimab Combined With Lenvatinib and SOX Versus SOX Alone in Patients With HER2-Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma [EARLY_Phase 1]
An early-phase (Phase 1) study evaluating pucotenlimab in combination with lenvatinib and the SOX regimen versus SOX alone in HER2-negative …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Camrelizumab and Apatinib in Patients With GC/GEJC [Phase 3]
A Phase 3 clinical trial is evaluating the efficacy and safety of combining Camrelizumab with Apatinib in patients with gastric cancer and g…