Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2014-02-17Clinical Trial Update: Icotinib Combined With WBRT For NSCLC Patients With Brain Metastases and EGFR Mutation [Phase 1, Phase 2]
Clinical trial update reporting Phase 1/2 evaluation of icotinib combined with whole-brain radiotherapy in EGFR-mutant non-small cell lung c…
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CLINICAL_TRIALS withdrawal · 2014-02-04Clinical Trial Update: Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases [Phase 3]
A Phase 3 trial comparing surgery plus whole-brain radiotherapy versus whole-brain radiotherapy with radiosurgery for 1-3 resectable brain m…
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer [Phase 1]
Phase 1 trial evaluating lapatinib in combination with radiation therapy for brain metastases from HER2-positive breast cancer. Results post…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Stereotactic Radiosurgery in Treating Patients With Brain Metastases [Phase 2]
This clinical trial update summarizes results from a Phase 2 study evaluating stereotactic radiosurgery for brain metastases; the trial was …
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CLINICAL_TRIALS trial_result · 2013-11-19Clinical Trial Update: Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases [Phase 3]
Phase 3 trial comparing radiation therapy with versus without radiosurgery for brain metastases has completed. The update notes the study st…
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CLINICAL_TRIALS research · 2013-11-06Clinical Trial Update: Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastatic Brain Neoplasm [Phase 1, Phase 2]
This ClinicalTrials.gov update describes a phase 1/2 study evaluating Carmustine followed by surgery in patients with recurrent supratentori…
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CLINICAL_TRIALS trial_result · 2013-11-01Clinical Trial Update: Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases [Phase 1]
A phase 1 clinical trial evaluating the combination of vorinostat with radiation therapy in patients with brain metastases has completed enr…
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CLINICAL_TRIALS trial_result · 2013-10-31Clinical Trial Update: Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Brain Metastases [Phase 3]
A Phase 3 trial evaluated the combination of radiation therapy with gadolinium texaphyrin for brain metastases and has completed.
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CLINICAL_TRIALS trial_result · 2013-10-16Clinical Trial Update: Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis [Phase 2]
A Phase 2 trial evaluating bevacizumab with etoposide and cisplatin in breast cancer patients with brain and/or leptomeningeal metastases ha…
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CLINICAL_TRIALS trial_result · 2013-10-09Clinical Trial Update: Epothilone B in Treating Patients With CNS Metastases From Breast Cancer [Phase 2]
Phase 2 trial of Epothilone B in patients with CNS metastases from breast cancer has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2013-10-01Clinical Trial Update: Sunitinib Malate After Stereotactic Radiosurgery in Treating Patients With Newly Diagnosed Brain Metastases [Phase 2]
Phase 2 trial evaluating Sunitinib Malate after stereotactic radiosurgery in patients with newly diagnosed brain metastases; the study was t…
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CLINICAL_TRIALS trial_result · 2013-09-12Clinical Trial Update: Safety Evaluation of a Combination of Brain Radiation Therapy and Bevacizumab (Avastin®) for Treatment of Brain Metastasis [Phase 1]
Phase 1 study evaluating the safety of combining brain radiotherapy with bevacizumab (Avastin) for brain metastases.
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CLINICAL_TRIALS trial_result · 2013-08-26Clinical Trial Update: Dexamethasone and Supportive Care With or Without Whole-Brain Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer That Has Spread to the Brain and Cannot Be Removed By Surgery [Phase 3]
Phase 3 trial evaluating dexamethasone with supportive care with or without whole-brain radiation therapy in patients with unresectable brai…
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CLINICAL_TRIALS research · 2013-08-12Clinical Trial Update: External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases [Phase 2]
A Phase 2 clinical trial is evaluating whether adding indinavir and ritonavir to external-beam radiation therapy improves outcomes for patie…
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CLINICAL_TRIALS trial_result · 2013-08-12Clinical Trial Update: Magnetic Resonance Imaging for the Early Detection of CNS Metastases in Women With Stage IV Breast Cancer [NA]
Clinical trial update describing a study using magnetic resonance imaging to enable early detection of brain metastases in women with stage …
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CLINICAL_TRIALS trial_result · 2013-07-31Clinical Trial Update: Electrochemotherapy as a Palliative Treatment for Brain Metastases [Phase 1]
Phase 1 trial evaluating electrochemotherapy as palliative treatment for brain metastases has been terminated.
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CLINICAL_TRIALS trial_result · 2013-07-25Clinical Trial Update: Markers of Prognosis and Response to Therapy in Patients With Metastatic Brain Tumors Undergoing Stereotactic Radiosurgery (SRS)
This study investigates biomarkers that predict prognosis and response to stereotactic radiosurgery in patients with brain metastases.
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CLINICAL_TRIALS trial_result · 2013-07-17Clinical Trial Update: A Phase II Safety and Tolerability Study of Bevacizumab When Added to Single-agent Chemotherapy to Treat Patient With Breast Cancer Metastatic to Brain [Phase 2]
A Phase II safety and tolerability trial evaluating adding bevacizumab to single-agent chemotherapy for breast cancer with brain metastases.…
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CLINICAL_TRIALS research · 2013-07-03Clinical Trial Update: VEGFRs Predict Bevacizumab Benefit in Advanced Non Small Cell Lung Cancer
Clinical trial update suggests VEGF receptor status may predict benefit from bevacizumab in advanced non-small cell lung cancer, including p…
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CLINICAL_TRIALS research · 2013-07-01Clinical Trial Update: Phase II Trial of Conventional Versus IMRT Whole Brain Radiotherapy for Brain Metastases [NA]
This clinical trial update describes a Phase II study comparing conventional whole-brain radiotherapy with IMRT-based whole-brain radiothera…
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CLINICAL_TRIALS trial_result · 2013-06-21Clinical Trial Update: Carmustine Implants in Treating Patients With Brain Metastases [Phase 2]
Phase 2 trial evaluating Carmustine implants for brain metastases has completed, coordinated by the New Approaches to Brain Tumor Therapy Co…
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CLINICAL_TRIALS trial_result · 2013-06-20Clinical Trial Update: Temozolomide in Treating Patients With Brain Metastases [Phase 2]
A completed Phase 2 trial evaluated temozolomide for patients with brain metastases.
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CLINICAL_TRIALS research · 2013-06-20Clinical Trial Update: Monoclonal Antibody Therapy in Treating Patients With Brain Metastases [Phase 1, Phase 2]
A completed Phase 1/Phase 2 clinical trial evaluated a monoclonal antibody therapy for brain metastases arising from metastatic cancer.
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CLINICAL_TRIALS withdrawal · 2013-06-13Clinical Trial Update: Surgery Versus Radiosurgery for the Treatment of Single Brain Metastases [NA]
The clinical trial NCT01295970 comparing surgery versus radiosurgery for a single brain metastasis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-06-06Clinical Trial Update: Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases [Phase 2]
A Phase 2 study sponsored by the NCI evaluated lapatinib for brain metastases in patients with stage IV HER2-positive breast cancer; the tri…