Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2015-03-20Clinical Trial Update: RCT of the 4mm vs. the 8mm Collimator for GKR of Brain Micrometastases [NA]
This randomized trial compares 4 mm versus 8 mm collimator sizes in Gamma Knife radiosurgery for brain micrometastases, and the current tria…
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CLINICAL_TRIALS research · 2015-03-11Clinical Trial Update: Temozolomide and Concomitant Whole Brain Radiotherapy in NSCLC Patients With Brain Metastases [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating temozolomide with concomitant whole-brain radiotherapy in patients with non-small cell lung cancer and b…
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: Lux-Breast 3; Afatinib Alone or in Combination With Vinorelbine in Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer Suffering From Brain Metastases [Phase 2]
Phase 2 trial update of afatinib alone or in combination with vinorelbine in HER2-positive breast cancer with brain metastases; results were…
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CLINICAL_TRIALS trial_result · 2015-02-06Clinical Trial Update: RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating RO4929097 with whole-brain radiation therapy or stereotactic radiosurgery for brain metastases from br…
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Erlotinib Plus Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating the combination of erlotinib and pemetrexed for lung adenocarcinoma with brain metastases has completed.
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CLINICAL_TRIALS research · 2015-01-26Clinical Trial Update: Comparator-Controlled Study for EGFR(+) Patients With Multiple BMs From NSCLC (BROKE) (EGFR-epidermal Growth Factor Receptor;BM-brain Metastases) [Phase 2, Phase 3]
An ongoing comparator-controlled trial (BROKE) is testing EGFR-mutant non-small cell lung cancer patients with multiple brain metastases in …
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CLINICAL_TRIALS trial_result · 2015-01-22Clinical Trial Update: An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma. [Phase 1, Phase 2]
This Clinical Trial Update reports the completion of an open-label Phase I/IIa dose-escalation study of 2B3-101 in patients with solid tumor…
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CLINICAL_TRIALS trial_result · 2014-12-31Clinical Trial Update: Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors [Phase 2]
A Phase 2 trial evaluating the combination of lapatinib with whole-brain radiotherapy for patients with brain metastases from lung or breast…
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CLINICAL_TRIALS research · 2014-12-23Clinical Trial Update: Erlotinib With Concurrent Brain Radiotherapy and Secondary Brain Radiotherapy After Recurrence With Erlotinib in NSCLC Non-increased-intracranial-pressure Symptomatic Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating erlotinib with concurrent brain radiotherapy and secondary brain radiotherapy after recurrence in patien…
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CLINICAL_TRIALS research · 2014-12-18Clinical Trial Update: Neurococognitive and Functioal Assessment of Patients With Brain Metastases
Clinical trial update on neurocognitive and functional assessment in patients with brain metastases, sponsored by Thomas Jefferson Universit…
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CLINICAL_TRIALS trial_result · 2014-12-15Clinical Trial Update: Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Patients With Brain Metastasis [Phase 3]
A Phase 3 intra-individual dose comparison trial of Magnevist in patients with brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2014-11-06Clinical Trial Update: High-dose Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases [Phase 2]
An update on a Phase 2 clinical trial evaluating high-dose pemetrexed for brain metastases from lung adenocarcinoma.
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CLINICAL_TRIALS research · 2014-09-26Clinical Trial Update: Study of EGFR-TKI to Asymptomatic Brain Metastases of NSCLC [Phase 2]
This clinical trial update describes a Phase 2 study evaluating an epidermal growth factor receptor tyrosine kinase inhibitor in patients wi…
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CLINICAL_TRIALS trial_result · 2014-08-21Clinical Trial Update: Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating radiolabeled monoclonal antibody therapy for primary or metastatic brain tumors has completed.
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Advanced Solid Tumors and Metastatic Brain Cancer [Phase 1]
This document reports the completion of a Phase 1, open-label, dose-escalation study of ANG1005 in patients with advanced solid tumors, with…
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CLINICAL_TRIALS withdrawal · 2014-07-24Clinical Trial Update: Evaluation of Cabazitaxel in Patients With Brain Metastasis Secondary to Breast Cancer and NSCLC [Phase 2]
A Phase 2 trial evaluating cabazitaxel for brain metastases arising from breast cancer and non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-07-23Clinical Trial Update: Icotinib Combined With Whole Brain Radiotherapy in Treating Multiple Brain Metastases From Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating the combination of icotinib with whole-brain radiotherapy for patients with multiple brain metastases from non-sm…
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CLINICAL_TRIALS trial_result · 2014-05-26Clinical Trial Update: Brain Metastasis in Breast Cancer Patients
The document is a completed clinical trial update from GlaxoSmithKline focused on brain metastases in breast cancer patients.
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CLINICAL_TRIALS trial_result · 2014-05-13Clinical Trial Update: Assess the Efficacy of Whole Brain Radiation Therapy in Lung Cancer Patients With Brain Metastasis [NA]
A clinical trial evaluating the efficacy of whole brain radiation therapy in lung cancer patients with brain metastases has been terminated.
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Study of Motexafin Gadolinium With Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients With Brain Metastases [Phase 2]
This is a Phase 2 clinical trial evaluating motexafin gadolinium with whole-brain radiation therapy followed by stereotactic radiosurgery bo…
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases [Phase 1]
A Phase 1 clinical trial evaluating riluzole in combination with whole-brain radiation therapy for patients with brain metastases has been t…
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CLINICAL_TRIALS trial_result · 2014-03-07Clinical Trial Update: Characterization of Brain Metastases
The document reports the completion status of a clinical trial characterizing brain metastases across cancers including lung cancer, breast …
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CLINICAL_TRIALS withdrawal · 2014-03-07Clinical Trial Update: Phase I Dose Escalation in Patients With 1-3 Unresectable Brain Metastases [Phase 1]
A Phase I dose-escalation trial in patients with 1-3 unresectable brain metastases was withdrawn, according to ClinicalTrials.gov.
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: A Study of GSK2118436 in BRAF Mutant Metastatic Melanoma to the Brain [Phase 2]
This update reports the completion of a Phase 2 study evaluating dabrafenib (GSK2118436) in patients with BRAF-mutant metastatic melanoma wi…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis. [Phase 1]
This Phase 1 trial assesses the safety of giving whole-brain radiation therapy (WBR) at the same time as intrathecal liposomal cytarabine (D…