Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-22Clinical Trial Update: Carboplatin and Bevacizumab for Progressive Breast Cancer Brain Metastases [Phase 2]
Phase 2 trial evaluating carboplatin combined with bevacizumab for progressive brain metastases from breast cancer has completed with result…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Temozolomide in Subjects With Brain Metastases of Either Malignant Melanoma, Breast, or Non-small Cell Lung Cancer (P02064) [Phase 2]
Phase 2 study evaluating temozolomide for brain metastases from melanoma, breast cancer, or non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Temozolomide for Treatment of Brain Metastases From Non-Small Cell Lung Cancer (Study P03247) [Phase 2]
Phase 2 trial of temozolomide for brain metastases from non-small cell lung cancer has completed; the study status is listed as COMPLETED.
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CLINICAL_TRIALS withdrawal · 2017-05-04Clinical Trial Update: 64-Cu Labeled Brain PET/MRI for MM-302 in Advanced HER2+ Cancers With Brain Mets [EARLY_Phase 1]
An early-phase trial of MM-302 in advanced HER2-positive cancers with brain metastases has been withdrawn.
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CLINICAL_TRIALS research · 2017-05-03Clinical Trial Update: Buparlisib in Melanoma Patients Suffering From Brain Metastases (BUMPER) [Phase 2]
Phase 2 clinical trial update for buparlisib in melanoma patients with brain metastases (BUMPER). The current status of the trial is UNKNOWN…
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CLINICAL_TRIALS withdrawal · 2017-04-21Clinical Trial Update: BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain [Phase 1, Phase 2]
This trial evaluating BBBD followed by methotrexate and carboplatin with or without trastuzumab for breast cancer with brain metastases has …
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases [NA]
A clinical trial comparing gadobutrol to gadopentetate dimeglumine or gadobenate dimeglumine before DCE-MRI in patients with multiple sclero…
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CLINICAL_TRIALS withdrawal · 2017-03-14Clinical Trial Update: Neurocognitive Outcomes In Patients Treated With Radiotherapy For Five Or More Brain Metastases [NA]
The clinical trial evaluating neurocognitive outcomes after radiotherapy for patients with five or more brain metastases has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-03-06Clinical Trial Update: Prophylactic Cranial Irradiation (PCI) Versus no PCI in Non Small Cell Lung Cancer After a Response to Chemotherapy [Phase 3]
Phase 3 trial comparing prophylactic cranial irradiation versus no PCI in non-small cell lung cancer patients after chemotherapy response; t…
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Icotinib or Whole Brain Irradiation in EGFR-mutant Lung Cancer [Phase 3]
A Phase 3 randomized trial comparing icotinib with whole brain irradiation in patients with EGFR-mutant non-small cell lung cancer and brain…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Response of Brain Metastases After Gamma-Knife Radiosurgery Using Dynamic Susceptibility-weighted Contrast-enhanced Perfusion Magnetic Resonance Imaging [Phase 1]
Phase 1 trial evaluating response of brain metastases to Gamma Knife radiosurgery, assessed with dynamic susceptibility-weighted contrast-en…
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CLINICAL_TRIALS other · 2017-02-23Clinical Trial Update: Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases [Phase 1]
Phase I trial evaluating temozolomide, valproic acid, and radiation therapy in patients with brain metastases; the study sponsored by H. Lee…
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: Toronto BNB Pilot Study
Clinical trial NCT02082587, the Toronto BNB Pilot Study, has completed.
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CLINICAL_TRIALS research · 2017-01-24Clinical Trial Update: Detection of CSF Next Generation Sequencing in the Application of Brain Metastases From Lung Adenocarcinoma or Meningeal Metastasis
A clinical trial sponsored by Shandong Cancer Hospital and Institute is evaluating cerebrospinal fluid next-generation sequencing for detect…
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CLINICAL_TRIALS research · 2017-01-23Clinical Trial Update: Tomotherapy for Refractory Brain Metastases [NA]
This clinical trial update discusses using Tomotherapy to treat refractory brain metastases. The current status of the trial is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2016-12-29Clinical Trial Update: Perfexion Brain Metastasis [Phase 1]
A Phase 1 clinical trial of Perfexion for brain metastases has been terminated.
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CLINICAL_TRIALS research · 2016-12-23Clinical Trial Update: Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer [NA]
Clinical trial update on hippocampal-sparing whole-brain radiotherapy for brain metastases arising from breast cancer. The current status of…
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CLINICAL_TRIALS research · 2016-11-23Clinical Trial Update: Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M [Phase 3]
Open-label Phase 3 study evaluating the efficacy and safety of osimertinib (AZD9291) in brain metastases from EGFR T790M-positive non-small …
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: A Study of Whole Brain Radiation Therapy and Capecitabine in Breast Cancer Participants With Newly Diagnosed Brain Metastasis [Phase 2]
This update reports the termination of a Phase 2 study evaluating whole brain radiation therapy in combination with capecitabine for breast …
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Using Intensity Modulated Radiation Therapy (IMRT) for Brain Metastases [Phase 1]
Phase 1 clinical trial evaluating the use of intensity modulated radiation therapy (IMRT) for brain metastases.
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Hypofractionated Stereotactic Radiation Therapy of Brain Metastases: Evaluation of Whole-brain Radiotherapy
The clinical trial evaluating hypofractionated stereotactic radiotherapy for brain metastases with evaluation of whole-brain radiotherapy ha…
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CLINICAL_TRIALS trial_result · 2016-09-22Clinical Trial Update: A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis [Phase 3]
Completed Phase 3 trial comparing postoperative whole-brain radiation therapy to salvage stereotactic radiosurgery for brain metastases.
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CLINICAL_TRIALS research · 2016-09-21Clinical Trial Update: Effect of TTFields (150kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-5 Brain Metastases Following Optimal Standard Local Treatment (COMET) [Phase 2]
Phase 2 COMET trial evaluating Tumor Treating Fields at 150 kHz in non-small cell lung cancer patients with 1-5 brain metastases after stand…
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CLINICAL_TRIALS trial_result · 2016-08-29Clinical Trial Update: Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases [Phase 1]
This Phase 1 trial assessed the maximum tolerated dose of vandetanib when given with whole brain radiotherapy in patients with non-small cel…
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: Phase Ⅲ Trial of WBRT Versus Erlotinib Concurrent Whole-brain Radiation Therapy as first-line Treatment for Patients With Multiple Brain Metastases From Non-small-cell Lung Cancer(ENTER): a Multicentre, Open-label, Randomised Study [Phase 3]
A multicenter Phase 3 randomized study comparing whole-brain radiation therapy alone to erlotinib given with WBRT as first-line treatment in…