Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-08-19Clinical Trial Update: Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma [Phase 1]
This Phase I study evaluates the safety and dosing of ipilimumab given with whole-brain radiation therapy or radiosurgery in patients with r…
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CLINICAL_TRIALS trial_result · 2019-08-19Clinical Trial Update: FSRT in Breast Cancer Patients With Brain Metastases [Phase 2]
Phase 2 clinical trial update evaluating frameless stereotactic radiotherapy (FSRT) in breast cancer patients with brain metastases.
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CLINICAL_TRIALS trial_result · 2019-08-15Clinical Trial Update: A Study to Determine the Efficiency For Brain Metastasis NSCLC Patients Treated With Icotinib Alone or Combined With Radiation Therapy [Phase 3]
Phase 3 trial evaluating icotinib alone vs icotinib with radiation therapy for brain metastases in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: MRI Study of Changes in Blood-Brain/Tumor-Barrier Permeability in Patients With Brain Metastases During and After Radiotherapy
A completed MRI study evaluating changes in blood-brain barrier permeability in brain metastases patients during and after radiotherapy.
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: HFSRT With Concurrent TMZ for Large BMs [Phase 3]
Phase 3 trial update on hypofractionated stereotactic radiotherapy (HFSRT) with concurrent temozolomide (TMZ) for large brain metastases.
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: A Study of Pyrotinib Plus Vinorelbine in Patients With Brain Metastases From HER2-positive Metastatic Breast Cancer [Phase 2]
Phase 2 trial evaluating pyrotinib plus vinorelbine in HER2-positive metastatic breast cancer patients with brain metastases.
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CLINICAL_TRIALS trial_result · 2019-04-25Clinical Trial Update: Bevacizumab in Pats w/ Recurrent ST Brain Metas Who Have Failed Whole Brain Radiation Therapy [Phase 2]
Phase 2 clinical trial evaluating bevacizumab in patients with recurrent brain metastases who failed whole brain radiation therapy; study co…
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CLINICAL_TRIALS trial_result · 2019-02-22Clinical Trial Update: Investigating the Efficacy of Hair Sparing Radiotherapy Treatment to the Whole Brain.
A terminated clinical trial evaluating hair-sparing whole-brain radiotherapy for metastatic brain cancer; no efficacy results are provided i…
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CLINICAL_TRIALS research · 2019-02-19Clinical Trial Update: High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating high-dose icotinib in combination with sequential stereotactic radiosurgery (SRS) for patients with EGFR…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Therapeutic Strategies in Patients With Non-squamous Non-small Cell Lung Cancer With Brain Metastases [Phase 3]
A Phase 3 trial in non-squamous non-small cell lung cancer with brain metastases has been terminated; no results are provided in this update…
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: CEST- Glucose Enhanced MRI for Metastatic Brain Tumours [Phase 2]
Phase 2 trial evaluating CEST glucose-enhanced MRI for metastatic brain tumors was terminated.
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CLINICAL_TRIALS trial_result · 2018-11-27Clinical Trial Update: Icotinib Combined With Radiation Therapy For NSCLC Patients With Brain Metastases and EGFR Mutation [Phase 2]
Phase 2 trial evaluating icotinib with radiation therapy for non-small cell lung cancer with brain metastases and EGFR mutation.
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CLINICAL_TRIALS trial_result · 2018-08-17Clinical Trial Update: Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites [Phase 2]
Phase II study evaluating dabrafenib and trametinib as pre- and post-operative therapy in melanoma patients with brain metastases; the trial…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery [Phase 3]
Phase 3 trial comparing stereotactic radiosurgery versus whole-brain radiation therapy for brain metastases post-surgery; study completed wi…
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Impact of Cognitive Rehab and Physical Activity on Cognition in Patients With Metastatic Brain Tumors Undergoing RT [NA]
A clinical trial evaluating cognitive rehabilitation and physical activity for cognition in patients with brain metastases undergoing radiat…
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CLINICAL_TRIALS trial_result · 2018-07-10Clinical Trial Update: TPI 287 in Breast Cancer Metastatic to the Brain [Phase 2]
Phase 2 clinical trial update for TPI 287 in breast cancer with brain metastases; trial completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors [Phase 1]
A Phase 1 trial of satraplatin in children and young adults with refractory solid tumors, including brain tumors, has completed.
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CLINICAL_TRIALS withdrawal · 2018-07-05Clinical Trial Update: Evaluation of Lucanthone to Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating lucanthone in combination with whole-brain radiation therapy for brain metastases from non-small cell lung cancer…
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: Quantitative MRI in Assessing Disease in Patients With Brain Tumors [NA]
The trial evaluating quantitative MRI for assessing disease in patients with brain tumors (NCT02269111) has been terminated.
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CLINICAL_TRIALS research · 2018-05-18Clinical Trial Update: Short Course Radiation Therapy in Palliative Treatment of Brain Metastases [NA]
This document provides an update on a clinical trial evaluating a short-course radiation therapy approach for palliation in patients with br…
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: Bendamustine and Radiation Therapy in Treating Patients With Brain Metastases Caused by Solid Tumors [Phase 1]
This Phase 1 trial evaluated bendamustine in combination with radiation therapy to treat brain metastases from solid tumors and has complete…
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CLINICAL_TRIALS research · 2018-05-17Clinical Trial Update: Protocol for Evaluating a Planning Algorithm for Gamma Knife Radiosurgery
This document describes a protocol to evaluate a planning algorithm for Gamma Knife radiosurgery across vestibular schwannoma, brain metasta…
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CLINICAL_TRIALS trial_result · 2018-05-14Clinical Trial Update: Dose Escalation/De-escalation Study of Pre-operative Stereotactic Radiosurgery for Brain Metastases(RAD 1002) [Phase 1]
Phase 1 dose escalation/de-escalation study evaluating pre-operative stereotactic radiosurgery for patients with brain metastases (RAD 1002)…
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: Observation for Patients With Asymptomatic CNS Metastatic Disease [Phase 2]
A Phase 2 trial evaluating observation for patients with asymptomatic CNS metastases has been completed.
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CLINICAL_TRIALS trial_result · 2018-04-20Clinical Trial Update: Irinotecan and Temozolomide in Treating Patients With Breast Cancer Who Have Received Previous Treatment for Brain Metastases [Phase 2]
Phase 2 trial evaluating irinotecan plus temozolomide in patients with breast cancer who previously had brain metastases. Results from the s…