Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Mesenchymal Stem Cells for Treatment of Amyotrophic Lateral Sclerosis (ALS) [Phase 1]
A Phase 1 clinical trial evaluating mesenchymal stem cells for the treatment of amyotrophic lateral sclerosis (ALS) has completed, as report…
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CLINICAL_TRIALS trial_result · 2012-04-13Clinical Trial Update: Safety, Tolerability, and Activity Study of ISIS SOD1Rx to Treat Familial Amyotrophic Lateral Sclerosis (ALS) Caused by SOD1 Gene Mutations [Phase 1]
Phase 1 study evaluating safety, tolerability, and activity of ISIS SOD1Rx in familial ALS caused by SOD1 mutations has completed.
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CLINICAL_TRIALS trial_result · 2012-03-14Clinical Trial Update: Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2, Phase 3]
This clinical trial evaluated Myobloc (rimabotulinumtoxinB) for reducing drooling in patients with Amyotrophic Lateral Sclerosis, and the st…
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CLINICAL_TRIALS trial_result · 2012-03-12Clinical Trial Update: Safety Study of High Doses of Zinc in ALS Patients [Phase 1, Phase 2]
This document reports the completion of a Phase 1/Phase 2 safety study evaluating high-dose zinc in patients with amyotrophic lateral sclero…
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CLINICAL_TRIALS trial_result · 2012-02-09Clinical Trial Update: A Multicenter, Dose Ranging Safety and Pharmacokinetics Study of Arimoclomol in ALS [Phase 2]
A multicenter Phase 2 study assessing safety and pharmacokinetics of arimoclomol in ALS has completed, reporting results from dose-ranging e…
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CLINICAL_TRIALS withdrawal · 2012-02-09Clinical Trial Update: A Multicenter, Double-Blind Study to Investigate the Safety and Efficacy of Arimoclomol in Volunteers With ALS [Phase 2]
A Phase 2 double-blind study of Arimoclomol for amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2011-12-06Clinical Trial Update: A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
A Phase 1/2 safety and tolerability study evaluating intracerebroventricular administration of sNN0029 in patients with amyotrophic lateral …
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CLINICAL_TRIALS trial_result · 2011-11-24Clinical Trial Update: A 12-week, Multicenter, Safety and Dose-ranging Study of 3 Oral Doses of TCH346 in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
A Phase 2 safety and dose-ranging study evaluating three oral doses of TCH-346 in patients with Amyotrophic Lateral Sclerosis has been compl…
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CLINICAL_TRIALS trial_result · 2011-11-24Clinical Trial Update: Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
This clinical trial update reports a Phase 2 study evaluating TCH346 versus placebo in amyotrophic lateral sclerosis that has completed. The…
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CLINICAL_TRIALS trial_result · 2011-11-23Clinical Trial Update: A Long-term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS) [Phase 2]
Phase 2 long-term extension results for TCH346 vs placebo in patients with Amyotrophic Lateral Sclerosis have been completed. The study spon…
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CLINICAL_TRIALS trial_result · 2011-10-21Clinical Trial Update: Talampanel for Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 trial of talampanel for amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2011-09-07Clinical Trial Update: Escitalopram (Lexapro) for Depression MS or ALS [Phase 3]
A Phase 3 trial evaluating escitalopram for depression in patients with multiple sclerosis or ALS has completed with results posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-07-25Clinical Trial Update: Modafinil for Treatment of Fatigue in ALS Patients [Phase 4]
Phase 4 clinical trial evaluating modafinil for fatigue in amyotrophic lateral sclerosis; results were posted in July 2011.
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CLINICAL_TRIALS research · 2011-06-22Clinical Trial Update: Study of the Role of G72 in Amyotrophic Lateral Sclerosis: Biomarker Discovery and Mechanism Investigation
A clinical trial investigating the role of the G72 gene in amyotrophic lateral sclerosis, focusing on biomarker discovery and mechanism inve…
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CLINICAL_TRIALS trial_result · 2011-05-12Clinical Trial Update: Validation of a New Device to Measure Neuromuscular Disease Progression
A completed clinical trial validating a new device intended to measure progression in amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2011-04-19Clinical Trial Update: Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS) [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating the safety and efficacy of lithium in volunteers with amyotrophic lateral sclerosis has been terminated, …
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CLINICAL_TRIALS trial_result · 2011-03-17Clinical Trial Update: Clinical Trial of High Dose CoQ10 in ALS [Phase 2]
This document reports the completion of a Phase 2 clinical trial evaluating high-dose Coenzyme Q10 in amyotrophic lateral sclerosis, with re…
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CLINICAL_TRIALS trial_result · 2011-03-02Clinical Trial Update: The Effect of Memantine on Functional Outcomes and Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 clinical trial evaluating memantine for functional outcomes and motor neuron degeneration in amyotrophic lateral sclerosis has compl…
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CLINICAL_TRIALS trial_result · 2011-02-01Clinical Trial Update: Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial update on a combination therapy selection trial for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS research · 2011-01-19Clinical Trial Update: Mitochondrial Functions and Oxidative Stress in ALS Patients
This document provides an update on a clinical trial examining mitochondrial function and oxidative stress in patients with amyotrophic late…
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CLINICAL_TRIALS trial_result · 2010-12-02Clinical Trial Update: Clinical Trial on the Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
Completed Phase 1/2 clinical trial evaluating autologous bone marrow-derived stem cells in patients with Amyotrophic Lateral Sclerosis.
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CLINICAL_TRIALS trial_result · 2010-10-25Clinical Trial Update: Efficacy and Safety of YAM80 in Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
A Phase 2 trial is evaluating the efficacy and safety of YAM80 in amyotrophic lateral sclerosis, sponsored by Yoshino Neurology Clinic; curr…
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CLINICAL_TRIALS trial_result · 2010-10-06Clinical Trial Update: Single-Ascending-Dose Safety/Tolerability of NP001 in Amyotrophic Lateral Sclerosis (ALS) [Phase 1]
Phase 1 single-ascending-dose study assessing safety and tolerability of NP001 in amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2010-09-13Clinical Trial Update: R(+)PPX High Dose Treatment of ALS [Phase 1, Phase 2]
A ClinicalTrials.gov entry reports completion of a Phase 1/2 study evaluating high-dose R(+)PPX for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2010-05-27Clinical Trial Update: Growth Hormone in Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial evaluating growth hormone (somatropin) in amyotrophic lateral sclerosis has completed.