Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS trial_result · 2013-08-26Clinical Trial Update: Extension Study of Talampanel for Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 extension study of talampanel for amyotrophic lateral sclerosis was terminated. The trial did not proceed further according to its s…
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CLINICAL_TRIALS trial_result · 2013-08-16Clinical Trial Update: Effects of Nocturnal Non-invasive Ventilation in Patients With Amyotrophic Lateral Sclerosis [NA]
A completed clinical trial evaluated the effects of nocturnal non-invasive ventilation in patients with amyotrophic lateral sclerosis.
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EMA guidance · 2013-08-01Guideline on medicines for the treatment of amyotrophic lateral sclerosis released for a six-month public consultation
The EMA released a guideline outlining medicines for treating amyotrophic lateral sclerosis (ALS) and opened it for a six-month public consu…
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CLINICAL_TRIALS research · 2013-07-12Clinical Trial Update: Communication by Brain - Computer Interface in Amyotrophic Lateral Sclerosis:Feasibility Study [NA]
Feasibility study evaluating a brain-computer interface to enable communication for individuals with amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS [Phase 3]
Phase 3 trial assessing safety and efficacy of AVP-923 for pseudobulbar affect in patients with ALS or MS; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: Trial of Early Noninvasive Ventilation for Amyotrophic Lateral Sclerosis (ALS) [Phase 1]
Phase 1 trial evaluating early noninvasive ventilation for Amyotrophic Lateral Sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2013-06-19Clinical Trial Update: Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease [Phase 2]
Phase 2 clinical trial of levetiracetam for cramps, spasticity and neuroprotection in motor neuron disease completed.
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FDA approval · 2013-06-18FDA Approved: RILUZOLE — Original Application (Glenmark Pharmaceuticals Inc., USA)
FDA approved the original application for riluzole (generic riluzole) from Glenmark Pharmaceuticals, marking approval of a generic riluzole …
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FDA approval · 2013-06-18FDA Approved: RILUZOLE — Original Application (Sun Pharmaceutical Industries, Inc.)
FDA approved Sun Pharmaceutical's riluzole via an original application as a generic product for the treatment of amyotrophic lateral scleros…
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Comparing The Cyberlink Control System to the Manual Letter Board for Communication Purposes in the ALS Patient Population
A completed clinical trial comparing the Cyberlink Control System to a manual letter board for communication in patients with amyotrophic la…
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Satisfaction Survey for Amyotrophic Lateral Sclerosis (ALS) Patients Comparing Rooms With and Without Assistive Technology
The clinical trial evaluating ALS patient satisfaction with rooms containing assistive technology versus standard rooms has been terminated.
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Noninvasive Examination of the Work of Breathing in Patients With Amyotrophic Lateral Sclerosis (ALS).
A clinical trial (NCT00718003) investigating noninvasive assessment of the work of breathing in patients with Amyotrophic Lateral Sclerosis …
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Assessment of the Cyberlink Control System for Use by the Amyotrophic Lateral Sclerosis (ALS) Patient
A clinical trial update indicating termination of the Cyberlink Control System study for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2013-02-15Clinical Trial Update: Insulin-like Growth Factor-1 in Amyotrophic Lateral Sclerosis (ALS) Trial [Phase 3]
Phase 3 trial evaluating insulin-like growth factor-1 for amyotrophic lateral sclerosis completed, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2012-11-30Clinical Trial Update: Combination Therapy in Amyotrophic Lateral Sclerosis (ALS) [Phase 1, Phase 2]
A completed Phase 1/Phase 2 trial update investigating a combination therapy for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2012-11-22Clinical Trial Update: A Study of NP001 in Subjects With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 study of NP001 in amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2012-11-19Clinical Trial Update: Neuromuscular Transmission in Amyotrophic Lateral Sclerosis [NA]
This clinical trial update reports the completion of a study investigating neuromuscular transmission in Amyotrophic Lateral Sclerosis. No p…
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CLINICAL_TRIALS trial_result · 2012-11-01Clinical Trial Update: Clinical Trial of SB-509 in Subjects With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
This clinical trial update indicates that the Phase 2 study of SB-509 in individuals with amyotrophic lateral sclerosis has been completed.
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: Effect of Lithium Carbonate in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial evaluating lithium carbonate in patients with amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS research · 2012-10-10Clinical Trial Update: Transcranial Direct Current Stimulation as a Novel Therapeutic Approach in Amyotrophic Lateral Sclerosis [Phase 2]
This clinical trial update reports on a Phase 2 study investigating transcranial direct current stimulation as a potential therapeutic appro…
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CLINICAL_TRIALS research · 2012-07-25Clinical Trial Update: Treating Amyotrophic Lateral Sclerosis (ALS) With R(+) Pramipexole Dihydrochloride Monohydrate at 60 mg/Day
This document provides an update on a clinical trial evaluating R(+) pramipexole dihydrochloride monohydrate at 60 mg/day for amyotrophic la…
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CLINICAL_TRIALS trial_result · 2012-06-20Clinical Trial Update: The Clinical Trial on the Use of Umbilical Cord Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial evaluating the use of umbilical cord mesenchymal stem cells for amyotrophic lateral sclerosis; the trial status is cu…
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: Placebo Controlled Study of ONO2506PO in the Presence of Riluzole in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 placebo-controlled trial evaluating ONO-2506PO in patients with amyotrophic lateral sclerosis, studied in the presence of riluzole; …
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: A Phase II Multi-centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnosed With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
This clinical trial update notes completion of a Phase II multi-centre extension study evaluating the long-term safety of ONO-2506PO in pati…
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CLINICAL_TRIALS trial_result · 2012-05-07Clinical Trial Update: Hyperlipidemia and Statin Therapy in Amyotrophic Lateral Sclerosis
A completed clinical trial investigated hyperlipidemia management and statin therapy in amyotrophic lateral sclerosis. The study was sponsor…