Amyotrophic Lateral Sclerosis
📧 Sign up to get email alerts when something new happens for Amyotrophic Lateral Sclerosis.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Clinical Procedures to Support Research in ALS
This clinical trial update outlines procedures to support research in amyotrophic lateral sclerosis and related motor neuron diseases, and t…
-
CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Phenotype, Genotype and Biomarkers 2
A University of Miami–sponsored clinical trial investigating phenotype, genotype, and biomarkers across motor neuron diseases, including ALS…
-
CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Blood-Brain Barrier Opening Using MR-Guided Focused Ultrasound in Patients With Amyotrophic Lateral Sclerosis [NA]
This update reports the completion of a clinical trial evaluating MRI-guided focused ultrasound to transiently open the blood-brain barrier …
-
CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: PRE-Symptomatic Studies in Amyotrophic Lateral Sclerosis
This entry reports an active-but-not-recruiting clinical trial focused on pre-symptomatic studies in amyotrophic lateral sclerosis, sponsore…
-
CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study
The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study is a University of Miami-sponsored clinical trial currently recr…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Clinical Research in ALS Study
A clinical trial studying amyotrophic lateral sclerosis is currently recruiting, sponsored by the University of Miami.
-
CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Spinal Cord Associative Plasticity for ALS [NA]
A clinical trial update shows that Spinal Cord Associative Plasticity for Amyotrophic Lateral Sclerosis is currently recruiting.
-
CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study to Evaluate the Safety, Efficacy, and Pharmacodynamics of PLL001 in ALS Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial to evaluate the safety, efficacy, and pharmacodynamics of PLL001 in patients with Amyotrophic Lateral Sclerosis (…
-
CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Characterization of Platelet Molecular Profiles in ALS for the Identification of Specific Diagnostic Biomarkers - A Pilot Study
A pilot clinical trial aiming to characterize platelet molecular profiles in amyotrophic lateral sclerosis to identify diagnostic biomarkers…
-
CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease [NA]
A clinical trial is evaluating the effects of whole-body electrical muscle stimulation on adults with various neuromuscular diseases and is …
-
CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Virtual Reality for Anxiety Management in Persons With Amyotrophic Lateral Sclerosis [NA]
A clinical trial is investigating virtual reality-based anxiety management for people with amyotrophic lateral sclerosis; the study is curre…
-
CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS
Clinical trial update on scalable expanded access to ibudilast for amyotrophic lateral sclerosis. The study includes analysis of neurofilame…
-
CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Ambulatory Versus Inpatient Initiation of Home Mechanical Ventilation [NA]
This clinical trial update concerns a study comparing ambulatory versus inpatient initiation of home mechanical ventilation in amyotrophic l…
-
CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Research of Traditional Chinese Medicine Oral Preparation of C. Cicadae in the Treatment of ALS Patients With Elevated Plasma Sphingolipids [Phase 2]
Phase 2 clinical trial protocol evaluating an oral Traditional Chinese Medicine preparation of C. Cicadae for amyotrophic lateral sclerosis …
-
CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Chinese-Specific Speech Imagery Coding Using High-Density ECoG [NA]
A clinical trial update indicates ongoing recruitment for a study on Chinese-specific speech imagery coding using high-density ECoG. The stu…
-
CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Effect of Terazosin on ATP Levels in People With Amyotrophic Lateral Sclerosis [EARLY_Phase 1]
An early-phase (Phase 1) clinical trial is assessing whether terazosin alters ATP levels in people with amyotrophic lateral sclerosis, with …
-
CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Expression Profile Study of Macrophages From Patients Affected by ALS or Other Related Motor Impairments
A clinical trial is currently recruiting to study expression profiles of macrophages from patients with amyotrophic lateral sclerosis and re…
-
CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis [Phase 1]
This clinical trial is a Phase 1 study evaluating LY4256984 in adults with sporadic amyotrophic lateral sclerosis, and it is currently recru…
-
CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS [Phase 2, Phase 3]
Clinical trial update for ibudilast (MN-166) in amyotrophic lateral sclerosis, outlining a 12-month treatment period followed by a 6-month o…
-
CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers? [NA]
A clinical trial update describes a study evaluating whether video recordings of multidisciplinary ALS clinics can improve quality of life f…
-
CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Amisodin in Healthy Adult Subjects With Amyotrophic Lateral Sclerosis [Phase 1]
This Phase 1 trial aims to evaluate the safety, tolerability, and pharmacokinetics of Amisodin in subjects with amyotrophic lateral sclerosi…
-
CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Social Cognition in Patients With Amyotrophic Lateral Sclerosis [NA]
The study is evaluating social cognition in patients with amyotrophic lateral sclerosis and is currently recruiting.
-
CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial [Phase 2, Phase 3]
A multi-arm adaptive randomized Phase 2/3 clinical trial for motor neuron disease/amyotrophic lateral sclerosis is currently recruiting, spo…
-
CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Efficacy and Safety of Tazbentetol in ALS Participants [Phase 2, Phase 3]
The document reports a Phase 2/Phase 3 clinical trial evaluating the efficacy and safety of Tazbentetol for amyotrophic lateral sclerosis, w…
-
CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS) [Phase 1, Phase 2]
Regeneron has initiated a first-in-human Phase 1/2 trial of ALN-SOD in adults with ALS caused by SOD1 gene mutations; the study is currently…