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CLINICAL_TRIALS research · 2026-02-27

Clinical Trial Update: First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS) [Phase 1, Phase 2]

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Summary

Regeneron has initiated a first-in-human Phase 1/2 trial of ALN-SOD in adults with ALS caused by SOD1 gene mutations; the study is currently recruiting.

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Diseases / indications

Drugs mentioned

  • ALN-SOD

Snippet

Sponsor: Regeneron Pharmaceuticals | Conditions: Amyotrophic Lateral Sclerosis (ALS), Mutation in the Superoxide Dismutase-1 (SOD1) Gene | Phase 1, Phase 2 | Status: RECRUITING