Amyotrophic Lateral Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Quality of Life Evaluation with the SRI Questionnaire of ALS Patient with Non-invasive Ventilation [NA]
A completed clinical trial evaluating quality of life in amyotrophic lateral sclerosis patients using non-invasive ventilation, assessed wit…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
A clinical trial update evaluating progression markers in neurodegenerative diseases, including Parkinson's disease, currently recruiting.
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders
The University of Massachusetts Worcester-sponsored genetic study on familial and sporadic amyotrophic lateral sclerosis/motor neuron diseas…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: HEALEY ALS Platform Trial - Regimen E SLS-005 - Trehalose [Phase 2, Phase 3]
Update on the HEALEY ALS Platform Trial Regimen E SLS-005 with trehalose is complete, and results have been posted. The study targets amyotr…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS) [Phase 3]
A Phase 3 safety extension study of oral edaravone in people with amyotrophic lateral sclerosis has completed, with results posted. The upda…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Fecal Microbiota Transplantation Effect on Amyotrophic Lateral Sclerosis Patients [NA]
A clinical trial evaluating the effect of fecal microbiota transplantation in patients with amyotrophic lateral sclerosis is currently activ…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: MRG-001 in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
This clinical trial update reports a Phase 2 study of MRG-001 in amyotrophic lateral sclerosis (ALS), which is currently not yet recruiting.
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Emotion Processing Among Patients With ALS
A clinical trial investigating emotion processing in patients with amyotrophic lateral sclerosis and related neuromuscular diseases; recruit…
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EMA approval · 2024-08-21EMA Authorised: Rilutek (riluzole) — Sanofi Winthrop Industrie
EMA authorised Rilutek (riluzole) for use in amyotrophic lateral sclerosis, with Sanofi Winthrop Industrie as the marketing authorisation ho…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Phase III Trial of AMX0035 for Amyotrophic Lateral Sclerosis Treatment [Phase 3]
Clinical trial update indicates AMX0035 is in a Phase III study for amyotrophic lateral sclerosis that is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031) [Phase 3]
Phase 3 open-label extension of COURAGE-ALS investigating CY 5031 was terminated; results were posted in August 2024.
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Reinnervation and Neuromuscular Transmission in ALS
A University of Aarhus-led clinical trial is currently recruiting to study reinnervation and neuromuscular transmission in amyotrophic later…
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CLINICAL_TRIALS other · 2024-08-07Clinical Trial Update: Gait Patterns in Dual-task Conditions in Patients With Amyotrophic Lateral Sclerosis
A clinical trial investigating gait patterns during dual-task conditions in patients with amyotrophic lateral sclerosis is not yet recruitin…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Magnetic Imaging for Diagnostic of Amyotrophic Lateral Sclerosis [NA]
A clinical trial sponsored by University Hospital, Toulouse is recruiting to evaluate magnetic imaging as a diagnostic tool for amyotrophic …
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Biological Sample Collection for Research and Biobanking
Termination notice for a New York Stem Cell Foundation Research Institute–led study collecting biological samples for research and biobankin…
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CLINICAL_TRIALS other · 2024-07-25Clinical Trial Update: SOD1 Kinetics Measurements in ALS Patients
A clinical trial (NCT03449212) investigating SOD1 kinetics in patients with familial and sporadic Amyotrophic Lateral Sclerosis has been sus…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Factors Associated With Success of NIPPV in ALS Patients
A completed clinical trial update examines factors associated with successful non-invasive ventilation in patients with amyotrophic lateral …
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EMA approval · 2024-07-09EMA Authorised: Qalsody (tofersen) — Biogen Netherlands B.V.
The European Medicines Agency authorised Qalsody (tofersen) for amyotrophic lateral sclerosis, with orphan medicine designation.
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
A Phase 2 clinical trial evaluating CNM-Au8, a therapeutic nanocatalyst, in slowing disease progression for amyotrophic lateral sclerosis ha…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: QCT in ALS Diagnosis, Mechanistic Understanding and Follow-up [NA]
An update on a clinical trial investigating the use of quantitative computed tomography (QCT) for diagnosing amyotrophic lateral sclerosis, …
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Remote Pulmonary Function Testing and Nurse Coaching in ALS [NA]
This clinical trial update reports results from a study evaluating remote pulmonary function testing and nurse coaching in amyotrophic later…
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: Patient's TeleMonitoring With Amyotrophic Lateral Sclerosis Treated by Non Invasive Ventilation at Home. [NA]
This clinical trial update reports the completion of a study evaluating telemonitoring for amyotrophic lateral sclerosis patients treated wi…
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CLINICAL_TRIALS approval · 2024-06-10Clinical Trial Update: Expanded Access Program for Tofersen in Participants With Superoxide Dismutase 1-Amyotropic Lateral Sclerosis
The document indicates that an expanded access program for tofersen in people with SOD1-ALS has been approved for marketing, enabling broade…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Phase 2, Randomized, Double Blind, Placebo Controlled Multicenter Study of Autologous MSC-NTF Cells in Patients With ALS [Phase 2]
Phase 2 randomized, double-blind, placebo-controlled multicenter study of autologous MSC-NTF cells in amyotrophic lateral sclerosis has comp…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Trial of Oxaloacetate in ALS [Phase 1]
Phase 1 trial of oxaloacetate for amyotrophic lateral sclerosis has completed.