Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: At-home Treatment With Cortico-spinal tDCS for Amyotrophic Lateral Sclerosis [NA]
A clinical trial is recruiting to evaluate at-home cortico-spinal transcranial direct current stimulation as a treatment for amyotrophic lat…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Platform Trial to Assess the Efficacy of Multiple Drugs in Amyotrophic Lateral Sclerosis (ALS) [Phase 3]
A Phase 3 platform trial to evaluate the efficacy of multiple drugs in Amyotrophic Lateral Sclerosis is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: ECoG BMI for Motor and Speech Control [NA]
This clinical trial update describes a study of an electrocorticography-based brain-machine interface for motor and speech control, currentl…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: High-Tech Rehabilitation Pathway for Chronic Adult Neuromuscular Diseases - Fit4MedRob-Chronic MND Project [NA]
A clinical trial entry for a high-tech rehabilitation pathway for chronic adult neuromuscular diseases, including ALS, CIDP, and Charcot-Mar…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: RolloverTreatment With Triumeq for People With ALS Following the Lighthouse II Trial [Phase 3]
A Phase 3 trial evaluating rollover treatment with Triumeq for amyotrophic lateral sclerosis has been terminated.
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Neurologic Stem Cell Treatment Study [NA]
Clinical trial update shows a neurologic stem cell treatment study sponsored by MD Stem Cells is currently recruiting. The study lists a wid…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Control of Assistive Devices Via Brain-Computer Interface Technology [NA]
A clinical trial update indicates that Neuralink's brain-computer interface study NCT06710626 is currently enrolling by invitation, investig…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices [NA]
A feasibility study of Neuralink's robotically implanted brain-computer interface to control external devices in people with tetraplegia and…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Systems Biology of Amyotrophic Lateral Sclerosis (ALS)
A new clinical trial by Viome investigating systems biology approaches for amyotrophic lateral sclerosis, currently not yet recruiting.
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Study to Explore the Role of Gut Flora in ALS
This clinical trial evaluating the role of gut flora in amyotrophic lateral sclerosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: CAN-PRIME: Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices [NA]
Neuralink's CAN-PRIME trial is evaluating a robotically implanted brain-computer interface to control external devices in people with tetrap…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: A 6-Month Extension Study to Assess the Long-Term Safety of Engensis in Amyotrophic Lateral Sclerosis [Phase 2]
A 6-month extension study to assess the long-term safety of Engensis in amyotrophic lateral sclerosis has completed, with results posted on …
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY) [Phase 3]
A Phase 3 study evaluating the efficacy and safety of MSC-NTF (NurOwn) in participants with early symptomatic amyotrophic lateral sclerosis,…
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Biomarkers in Different Types of Amyotrophic Lateral Sclerosis (ALS) Patients Being Treated With Edaravone
A study at Loma Linda University is evaluating biomarkers across different types of amyotrophic lateral sclerosis in patients treated with e…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Development of Targeted RNA-Seq for Amyotrophic Lateral Sclerosis Diagnosis
Clinical trial update indicates development of targeted RNA-Seq for diagnosing Amyotrophic Lateral Sclerosis. The study is currently recruit…
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CLINICAL_TRIALS research · 2025-05-19Clinical Trial Update: Holter of Movement in Patients With Amyotrophic Lateral Sclerosis.
This entry outlines a clinical trial titled 'Holter of Movement in Patients With Amyotrophic Lateral Sclerosis' that is currently recruiting…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: A Second Intermediate-Size Expanded Access Protocol (EAP) for Pridopidine in People With Amyotrophic Lateral Sclerosis (Pridopidine EAP 2)
This clinical trial update indicates that the second intermediate-size Expanded Access Protocol for pridopidine in people with amyotrophic l…
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit [NA]
A completed clinical trial update on the Optimizing BCI-FIT toolkit (Brain Computer Interface - Functional Implementation Toolkit) sponsored…
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EMA approval · 2025-05-15EMA Authorised: Riluzole Zentiva (riluzole) — Zentiva k.s.
The European Medicines Agency authorised Riluzole Zentiva (riluzole) by Zentiva k.s. for Amyotrophic Lateral Sclerosis on 15 May 2025.
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease [NA]
A completed clinical trial evaluating acute intermittent hypoxia and breathing in amyotrophic lateral sclerosis and other neuromuscular dise…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Contribution of Diaphragmatic Ultrasound for Monitoring Diaphragmatic Function in Patients With Amyotrophic Lateral Sclerosis
A clinical trial investigating diaphragmatic ultrasound to monitor diaphragmatic function in patients with amyotrophic lateral sclerosis. It…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Creation of a Clinical Database for the Study of Phenotypic Variability in Motor Neuron Diseases
This update describes the creation of a clinical database to study phenotypic variability in motor neuron diseases, including amyotrophic la…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis
This clinical trial update notes a biomarker-driven study aimed at dissecting ALS phenotypes is currently recruiting, including conditions s…
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Safety of Engensis in Participants With Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 safety update for Engensis (VM202) in participants with amyotrophic lateral sclerosis. Results have been posted.
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: The Study Evaluating the Improvement of Nutritional Status and Frailty With Silkworm Pupa Powder Among Patients With Motor Neuron Disease [NA]
A clinical trial update shows recruitment is ongoing for a study evaluating silkworm pupa powder to improve nutritional status and frailty i…