Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CD45RA-depleted stem cell addback to prevent viral or fungal infections following TCRab/CD19-deplet…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Patients With Measurable Residual Disease Positive B-cell Acute Lymphoblastic Leukemia [Phase 2]
This Phase 2 clinical trial update describes evaluating subcutaneous blinatumomab for safety and efficacy in patients with measurable residu…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Real World Asparaginase Therapy Toxicity
An update on a real-world study examining toxicity associated with asparaginase therapy, sponsored by St. Jude Children's Research Hospital;…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Massage Impact on Sleep in Pediatric Oncology [NA]
A pediatric oncology clinical trial from Children's Hospital of Philadelphia is investigating whether massage can improve sleep for children…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Anti-CD19/20/22 Chimeric Antigen Receptor T Cells (TriCAR19.20.22 T Cells) for the Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, and Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 trial evaluating TriCAR19.20.22 T cells, a CD19/20/22-targeting CAR-T therapy, for relapsed or refractory non-Hodgkin lymphoma, acut…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Creation of a Biocollection of Patients With Acute Myeloid Leukemia (AML) or Lymphoid Leukemia (ALL) or High-risk Myelodysplastic Syndrome (MDS) Monitored at the Nantes University Hospital
This clinical trial update describes the creation of a biocollection of patients with acute myeloid leukemia, acute lymphoblastic leukemia, …
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FDA approval · 2026-04-14FDA Approved: DANZITEN — Supplemental Application (Azurity Pharmaceuticals, Inc.)
The FDA approved a supplemental application for Danziten (nilotinib) submitted by Azurity Pharmaceuticals, Inc. The supplement adds to the e…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update. It evaluates a conditioning strategy using chemotherapy, total body irradiation, and post-transpl…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: ONC201 in Treating Patients With Relapsed or Refractory Acute Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating ONC201 for relapsed or refractory acute lymphoblastic leukemia, relapsed or refractory acute mye…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Role of T Lymphocytes in Hypersensitivity Reactions to Asparaginase in Patients Treated for Acute Lymphoblastic Leukemia. [NA]
This clinical trial investigates the role of T lymphocytes in hypersensitivity reactions to asparaginase in patients with acute lymphoblasti…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of 14C-Bleximenib (Radiolabeled) in Participants With Acute Leukemia [Phase 1]
A Phase 1 clinical trial evaluating a radiolabeled 14C-Bleximenib in patients with acute leukemia. The study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) [Phase 1, Phase 2]
Phase I/II trial evaluating an engineered donor graft named Orca Q for pediatric hematopoietic cell transplantation is currently suspended. …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients
A clinical trial update describes using Whole Genome Sequencing (ChromoSeq) for patients with Acute Lymphoblastic Leukemia and indicates the…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: UAB 2419-CD34 Selection Using the Automated CliniMACS Prodigy [Phase 1]
Phase 1 clinical trial sponsored by the University of Alabama at Birmingham evaluating UAB 2419-CD34 selection using the CliniMACS Prodigy s…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia [Phase 2]
This Phase 2 trial is evaluating combinations of inotuzumab ozogamicin, blinatumomab with or without ponatinib for newly diagnosed, recurren…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen
Prospective collection, storage, and reporting of data on patients undergoing hematopoietic stem cell transplantation using a standard prepa…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma [Phase 1]
A Phase 1 trial evaluating consolidation with CD45RA-depleted CD19-CAR T cells after haploidentical hematopoietic cell transplantation in re…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: UNDERSTANDING THE T-CELL AND B-CELL RECEPTOR REPERTOIRE IN CHILDREN AND YOUNG ADULTS WITH ANTI-DRUG ANTIBODIES AGAINST PEG ASPARAGINASE
This clinical trial update describes research into the T-cell and B-cell receptor repertoires in children and young adults who have develope…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Physical Activity and Exercise During Early Treatment Phases for Childhood Acute Lymphoblastic Leukaemia to Protect Against Muscle Loss and Improve Frailty Outcomes [NA]
A clinical trial evaluating physical activity and exercise during early treatment of childhood acute lymphoblastic leukemia to protect again…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Quality of Life in Pediatric Patients With Acute Lymphoblastic Leukemia Receiving Maintenance Chemotherapy [NA]
A pediatric acute lymphoblastic leukemia trial evaluating quality of life during maintenance chemotherapy has been suspended. The current st…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation [NA]
This entry notes a clinical trial exploring an eHealth mindfulness-based music therapy intervention for patients undergoing stem cell transp…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia [Phase 3]
This entry provides a Phase 3 clinical trial protocol update for Interfant-21 in infants under 1 year with KMT2A-rearranged acute lymphoblas…
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CLINICAL_TRIALS other · 2026-04-13Clinical Trial Update: Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia [NA]
Clinical trial evaluating brain MRI feasibility (Brain MRF) in children, adolescents, and young adults with acute leukemia is currently susp…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
A multicenter protocol to improve access and distribution of unlicensed cryopreserved cord blood units, with the study currently recruiting.…
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EMA approval · 2026-04-09EMA Authorised: Iclusig (ponatinib) — Incyte Biosciences Distribution B.V.
The European Medicines Agency authorised Iclusig (ponatinib) from Incyte Biosciences Distribution B.V. for certain leukemias, including chro…