Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Results: Innovative Prosthetic Systems for Pediatric Limb Loss to Accommodate Growth [NA]
Completed clinical trial investigating innovative prosthetic systems for pediatric limb loss to accommodate growth; results posted.
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CLINICAL_TRIALS trial_result · 2026-06-29Clinical Trial Update: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome [Phase 3]
Phase 3 trial comparing mismatched related donor versus matched unrelated donor stem cell transplantation in pediatric and young adult patie…
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Results: Ibrutinib and Blinatumomab in Treating Patients With Relapsed or Refractory B Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating the combination of ibrutinib and blinatumomab in relapsed or refractory adult B-ALL, including Philadelphia chromos…
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CLINICAL_TRIALS trial_result · 2026-06-03Clinical Trial Results: Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy [Phase 2]
Phase 2 trial evaluating siltuximab for treating cytokine release syndrome and ICANS associated with CAR-T cell therapy; study completed wit…
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CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Update: Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma [Phase 3]
A Phase 3 trial evaluating levocarnitine for protecting the liver during chemotherapy in various B-cell acute lymphoblastic leukemia and rel…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating CD22 CAR T-cells to extend remission after CD19 CAR T-cell therapy in children, adolescents, and adults wi…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia [Phase 2]
Phase 2 study recruiting to test adding venetoclax and/or blinatumomab to standard chemotherapy in infants with newly diagnosed KMT2A-rearra…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies [Phase 1]
Phase 1 trial evaluating anti-CD22 CAR T cells in pediatric and young adult patients with recurrent or refractory CD22-expressing B-cell mal…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies [Phase 1]
Phase 1 clinical trial evaluating autologous T cells engineered with retroviral vectors to express TCRs against patient-specific neoantigens…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Phase Ib/II Study Assessing the Clinical Activity and Safety of Brexucabtagene Autoleucel as a Consolidation in Patients With Relapsed/Refractory (R/R) and Newly Diagnosed B-cell Acute Lymphocytic Leukemia (ALL) Post Cytoreduction With Mini-HCVD-inotuzumab-blinatumomab/HCVAD-inotuzumab-blinatumomab [Phase 1, Phase 2]
Phase Ib/II clinical trial evaluating brexucabtagene autoleucel as consolidation therapy in relapsed/refractory and newly diagnosed B-cell a…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission [Phase 1]
This clinical trial update describes a Phase 1 CD19-directed CAR-T cell therapy trial for older adults with acute lymphoblastic leukemia in …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression [Phase 1, Phase 2]
AstraZeneca is evaluating AZD3632 as monotherapy or with other anticancer agents in adults with advanced hematologic malignancies associated…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity [Phase 2]
A Phase 2 clinical trial is evaluating resistance exercise plus an incretin-mimetic therapy to improve cardiometabolic health in survivors o…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia [NA]
This clinical trial update describes a study evaluating transcutaneous auricular vagus nerve stimulation for insomnia in survivors of childh…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu... [NA]
This ClinicalTrials.gov entry describes a recruiting study evaluating next-generation sequencing for monitoring B-cell recovery to guide man…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: CAR-T Immunotherapy Targeting CD19- ALL [Phase 1, Phase 2]
This document updates a Phase 1/Phase 2 clinical trial of a CD19-targeted CAR-T cell therapy for B-cell acute lymphoblastic leukemia, sponso…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Childhood Cancer Survivors' Affective Response to Exercise
An ongoing clinical trial is evaluating how exercise affects affective responses in survivors of childhood cancer, including those with acut…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia [Phase 2]
Phase 2 study evaluating a condensed regimen (mini-Hyper-CVD with rituximab, inotuzumab ozogamicin, and blinatumomab) for relapsed pediatric…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study on the Efficacy and Safety of the TmBU Conditioning Regimen in High-risk or Relapsed/Refractory Acute Leukemia [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of the TmBU Conditioning Regimen in high-risk or relapsed/refractory acute leuke…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Characterizing Sleep Among Long-term Survivors of Childhood Cancer
This clinical trial update describes a study examining sleep among long-term survivors of childhood cancer and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors [NA]
A clinical trial sponsored by St. Jude Children's Research Hospital is recruiting to assess skeletal muscle mitochondrial oxidative phosphor…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer [NA]
Trial update indicates the NCT05550948 study on transcranial photobiomodulation to improve cognition in childhood cancer survivors is curren…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Pilot Imaging Study of Leukemia [Phase 1]
Phase 1 pilot imaging study in leukemia is currently recruiting. Conditions listed include acute lymphoblastic leukemia, acute myeloid leuke…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication Adherence: Study 3 [NA]
This clinical trial update indicates recruitment is ongoing for Study 3 investigating behavioral parenting skills to improve pediatric medic…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL [Phase 2]
A Phase 2 pediatric study to learn more about Inotuzumab Ozogamicin (InO) for first relapse acute lymphoblastic leukemia in children aged 1 …