Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer
This is a clinical trial update describing a longitudinal study that assesses frailty in young adult survivors of childhood cancer; the stud…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Safety of Clofarabine With Multiagent Chemotherapy in Childhood Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 study assessing the safety of combining clofarabine with multiagent chemotherapy in children with relapsed acute lymphoblastic leuke…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia [Phase 2]
This clinical trial update describes a Phase 2 study of revumenib in combination with chemotherapy for relapsed or refractory leukemia, with…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Biology Studies of Hematologic Cancers
The document reports an NCI-sponsored biology-focused clinical trial update in hematologic cancers, with enrollment by invitation for condit…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: CAR-T Cell Therapy Targeting to CD19 for R/R ALL [Phase 1, Phase 2]
An ongoing phase 1/2 clinical trial is evaluating a CD19-targeted CAR-T cell therapy for relapsed/refractory acute lymphoblastic leukemia, c…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Predictive Clinical and Biological Parameters in Acute Leukemia, Myelodysplastic Syndromes and Myeloproliferative Disorders-HEMATO-BIO-IPC-2013-015 [NA]
This clinical trial update reports on predictive clinical and biological parameters across acute leukemia, myelodysplastic syndromes, and my…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: CAR T-cell Therapy in Patients With Renal Dysfunction [Phase 2]
A Phase 2 clinical trial evaluating CAR T-cell therapy in patients with renal dysfunction is currently recruiting for indications including …
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Pilot Prospective Study for PET-CT Imaging in Participants With Relapsed/Refractory Acute Leukemias
An NCI-sponsored pilot prospective study evaluates PET-CT imaging in participants with relapsed/refractory B-cell acute lymphoblastic leukem…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial (TINI 2) evaluating total therapy for infants with acute lymphoblastic leukemia, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial is investigating intrathecal chemoprophylaxis to prevent neurotoxicity from blinatumomab in patients with acute lym…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing
A clinical trial update describing leukapheresis collection for manufacturing CAR or adoptive cell therapies, with enrollment by invitation …
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Palbociclib in Combo w/Chemotherapy in Peds Relapsed/Refractory Acute Lymphoblastic Leukemia [Phase 1]
A Phase 1 trial of palbociclib in combination with chemotherapy for pediatric patients with relapsed or refractory acute lymphoblastic leuke…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL [Phase 1, Phase 2]
Phase I/II clinical trial update describing the study of Rapcabtagene Autoleucel in chronic lymphocytic leukemia, small lymphocytic lymphoma…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Efficacy and Safety of Inotuzumab Ozogamicin in Treating Adult Patients With Ph Negative ALL With Minimal Residual Disease Positive After Induction Chemotherapy [Phase 2]
This phase 2 clinical trial update assesses the efficacy and safety of Besponsa (inotuzumab ozogamicin) in adults with Philadelphia-negative…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia [Phase 3]
This Phase 3 clinical trial is recruiting and compares blinatumomab alternating with low-intensity chemotherapy against standard-of-care che…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL [NA]
This clinical trial is evaluating a combination of ABL and JAK inhibitors with chemotherapy and venetoclax for Philadelphia-like acute lymph…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM) [Phase 1]
Phase 1 clinical trial update for MB-CART19.1 in CD19+ B-cell malignancies sponsored by Miltenyi Biomedicine GmbH. The study includes recurr…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors [Phase 1, Phase 2]
The document reports ongoing Phase 1/2 clinical trials evaluating ponatinib in pediatric patients with recurrent or refractory leukemias, ly…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation [Phase 2]
Phase 2 trial of Inotuzumab ozogamicin combined with chemotherapy in leukemia and lymphoma patients undergoing stem cell transplantation was…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating a two-step reduced-intensity conditioning approach for bone marrow transplant in adults with hematologic malignanci…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating ponatinib in combination with chemotherapy for acute lymphoblastic leukemia and BCR-ABL1-positive leukemias, includ…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Multi-modality Imaging and Collection of Biospecimen Samples in Understanding Bone Marrow Changes in Patients With Acute Myeloid Leukemia Undergoing TBI and Chemotherapy [EARLY_Phase 1]
An early-phase study at City of Hope evaluating imaging techniques and biospecimen collection to understand bone marrow changes in patients …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Establishment of a Phamacokinetik Model for Erwinase Pharmacokinetiks: The Aim of This Sub Study is to Optimize Target Trough Attainment While Minimizing High Exposures That Impose Increased Risk of Side Effects Such as Hyperammonemia
This clinical trial sub-study aims to develop a pharmacokinetic model for Erwinase (L-asparaginase from Erwinia chrysanthemi) to optimize tr…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia [Phase 1]
A Phase 1 clinical trial from MD Anderson tests combinations of palbociclib with sorafenib, decitabine, or dexamethasone in patients with re…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors [NA]
A clinical trial update describing a high-intensity electronic health intervention aimed at reducing learning disparities among childhood ca…