Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Results: Innovative Prosthetic Systems for Pediatric Limb Loss to Accommodate Growth [NA]
Completed clinical trial investigating innovative prosthetic systems for pediatric limb loss to accommodate growth; results posted.
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CLINICAL_TRIALS trial_result · 2026-06-29Clinical Trial Update: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome [Phase 3]
Phase 3 trial comparing mismatched related donor versus matched unrelated donor stem cell transplantation in pediatric and young adult patie…
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Results: Ibrutinib and Blinatumomab in Treating Patients With Relapsed or Refractory B Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating the combination of ibrutinib and blinatumomab in relapsed or refractory adult B-ALL, including Philadelphia chromos…
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CLINICAL_TRIALS trial_result · 2026-06-03Clinical Trial Results: Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy [Phase 2]
Phase 2 trial evaluating siltuximab for treating cytokine release syndrome and ICANS associated with CAR-T cell therapy; study completed wit…
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CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Update: Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma [Phase 3]
A Phase 3 trial evaluating levocarnitine for protecting the liver during chemotherapy in various B-cell acute lymphoblastic leukemia and rel…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial evaluating CD22 CAR T-cells to extend remission after CD19 CAR T-cell therapy in children, adolescents, and adults wi…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies [Phase 1]
Phase 1 trial evaluating anti-CD22 CAR T cells in pediatric and young adult patients with recurrent or refractory CD22-expressing B-cell mal…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies [Phase 1]
Phase 1 clinical trial evaluating autologous T cells engineered with retroviral vectors to express TCRs against patient-specific neoantigens…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Safety of Clofarabine With Multiagent Chemotherapy in Childhood Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 study assessing the safety of combining clofarabine with multiagent chemotherapy in children with relapsed acute lymphoblastic leuke…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Predictive Clinical and Biological Parameters in Acute Leukemia, Myelodysplastic Syndromes and Myeloproliferative Disorders-HEMATO-BIO-IPC-2013-015 [NA]
This clinical trial update reports on predictive clinical and biological parameters across acute leukemia, myelodysplastic syndromes, and my…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Pilot Prospective Study for PET-CT Imaging in Participants With Relapsed/Refractory Acute Leukemias
An NCI-sponsored pilot prospective study evaluates PET-CT imaging in participants with relapsed/refractory B-cell acute lymphoblastic leukem…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Palbociclib in Combo w/Chemotherapy in Peds Relapsed/Refractory Acute Lymphoblastic Leukemia [Phase 1]
A Phase 1 trial of palbociclib in combination with chemotherapy for pediatric patients with relapsed or refractory acute lymphoblastic leuke…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL [Phase 1, Phase 2]
Phase I/II clinical trial update describing the study of Rapcabtagene Autoleucel in chronic lymphocytic leukemia, small lymphocytic lymphoma…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Efficacy and Safety of Inotuzumab Ozogamicin in Treating Adult Patients With Ph Negative ALL With Minimal Residual Disease Positive After Induction Chemotherapy [Phase 2]
This phase 2 clinical trial update assesses the efficacy and safety of Besponsa (inotuzumab ozogamicin) in adults with Philadelphia-negative…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM) [Phase 1]
Phase 1 clinical trial update for MB-CART19.1 in CD19+ B-cell malignancies sponsored by Miltenyi Biomedicine GmbH. The study includes recurr…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors [Phase 1, Phase 2]
The document reports ongoing Phase 1/2 clinical trials evaluating ponatinib in pediatric patients with recurrent or refractory leukemias, ly…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation [Phase 2]
Phase 2 trial of Inotuzumab ozogamicin combined with chemotherapy in leukemia and lymphoma patients undergoing stem cell transplantation was…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating a two-step reduced-intensity conditioning approach for bone marrow transplant in adults with hematologic malignanci…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating ponatinib in combination with chemotherapy for acute lymphoblastic leukemia and BCR-ABL1-positive leukemias, includ…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update. It evaluates a conditioning strategy using chemotherapy, total body irradiation, and post-transpl…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) [Phase 1, Phase 2]
Phase I/II trial evaluating an engineered donor graft named Orca Q for pediatric hematopoietic cell transplantation is currently suspended. …
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma [Phase 1]
Phase I clinical trial update for ThINKK Adoptive Immunotherapy after allogeneic hematopoietic stem cell transplantation in children with ac…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission [Phase 3]
A completed Phase 3 trial sponsored by the Children's Oncology Group assessed adherence to mercaptopurine therapy in younger children with a…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Expanded Access Study for the Treatment of Patients With Commercially Out-of-Specification Brexucabtagene Autoleucel
Expanded access study for brexucabtagene autoleucel (Tecartus) for mantle cell lymphoma and acute lymphoblastic leukemia is currently availa…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in Oncology [NA]
A completed clinical trial examined whether a high-fiber, low-fat diet can prevent recurrent Clostridioides difficile infection in oncology …