Clinical Trial Update: Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]

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Summary

This is a Phase 1/2 clinical trial update. It evaluates a conditioning strategy using chemotherapy, total body irradiation, and post-transplant cyclophosphamide…

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Diseases / indications

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• Chronic Myeloid Leukemia
• Hodgkin Lymphoma
• Myelodysplastic Syndrome
• Myelomonocytic Leukemia
• Myeloproliferative Neoplasm
• Non-hodgkin Lymphoma

Drugs mentioned

• Cytoxan (cyclophosphamide)

Snippet

Sponsor: Roswell Park Cancer Institute | Conditions: Acute Myeloid Leukemia in Remission, Adult Acute Lymphoblastic Leukemia in Complete Remission | Phase 1, Phase 2 | Status: ACTIVE_NOT_RECRUITING | Results posted: 2026-04-14