Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma [Phase 1]
Phase I clinical trial update for ThINKK Adoptive Immunotherapy after allogeneic hematopoietic stem cell transplantation in children with ac…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults [NA]
Overview of the my.naviGATE guide for after-treatment effects in adolescents and young adults with sarcoma and related cancers; the study is…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission [Phase 3]
A completed Phase 3 trial sponsored by the Children's Oncology Group assessed adherence to mercaptopurine therapy in younger children with a…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study of TSC-100 and TSC-101 in AML, ALL and MDS in Patients Undergoing Allogeneic Peripheral Blood Stem Transplantation [Phase 1]
This is a Phase 1 trial update announcing ongoing recruitment for a study evaluating TSC-100 and TSC-101 in patients with acute myeloid leuk…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study [Phase 1, Phase 2]
PedAL BCU, LLC is conducting a pediatric screening trial to test bone marrow and blood methods in children with relapsed or hard-to-treat ac…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Backtracking Leukemia-Typical Somatic Mutations in Cord Blood
A clinical trial is actively recruiting to study leukemia-associated somatic mutations in cord blood for acute lymphoblastic leukemia and ac…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Expanded Access Study for the Treatment of Patients With Commercially Out-of-Specification Brexucabtagene Autoleucel
Expanded access study for brexucabtagene autoleucel (Tecartus) for mantle cell lymphoma and acute lymphoblastic leukemia is currently availa…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in Oncology [NA]
A completed clinical trial examined whether a high-fiber, low-fat diet can prevent recurrent Clostridioides difficile infection in oncology …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
A clinical trial is enrolling people with and without cancer to collect blood samples and evaluate tests for early cancer detection across m…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: The Association Between Gut Microbiome Composition Signature and Cancer-related Symptoms in Children With Acute Lymphoblastic Leukemia
This clinical trial update reports on a study investigating how gut microbiome composition relates to cancer-related symptoms in children wi…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Blinatumomab and Tyrosine Kinase Inhibitor Therapy in People With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial update evaluating the combination of blinatumomab with a tyrosine kinase inhibitor in Philadelphia chromosome-positiv…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Prophylactic and Therapeutic DLI-X for Leukemia Relapse After HCT [Phase 1]
Phase 1 clinical trial update on DLI-X as a prophylactic and therapeutic donor lymphocyte infusion to prevent or treat leukemia relapse afte…
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FDA approval · 2026-04-06FDA Approved: IMATINIB MESYLATE — Supplemental Application (BluePoint Laboratories)
FDA approved BluePoint Laboratories' supplemental application for Imatinib Mesylate (ANDA 212773), approving a generic version of the cancer…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study [NA]
Completed clinical trial evaluating a geriatric optimization plan to improve survival in older adults undergoing allogeneic hematopoietic ce…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT) [NA]
This clinical trial update describes a study evaluating reduced-intensity conditioning with 200 cGy versus 400 cGy total body irradiation in…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies [Phase 2]
Phase 2 clinical trial evaluating MT2021-08T, a T-cell receptor alpha/beta-depleted donor peripheral blood stem cell product, for hematologi…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest [NA]
A completed clinical trial evaluated two resuscitation sequences for managing simulated pediatric cardiac arrest.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: The Role of Serum Cytokines IL_17 A and IL_10 in Disease Activity of Acute B Lymphoblastic Leukemia in South Egypt
A clinical trial is investigating the role of serum cytokines IL-17A and IL-10 in disease activity of B-cell acute lymphoblastic leukemia in…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Phase 1/2 Study of T-cell Expressing a Novel CD19 Chimeric-Antigen Receptor (SHB-02-CD19) in Patients With CD19-expressing B-cell Malignancies [Phase 1, Phase 2]
Phase 1/2 trial update for SHB-02-CD19, a novel CD19-directed CAR-T therapy, in CD19-expressing B-cell malignancies; recruitment not yet sta…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy [Phase 3]
A Phase 3 trial evaluating adding inotuzumab ozogamicin to post-induction chemotherapy for high-risk acute lymphoblastic leukemia, mixed phe…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic Leukemia (B-ALL) [Phase 2]
Phase 2 clinical trial update for KTE-X19 in minimal residual disease–positive B-cell acute lymphoblastic leukemia, currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Nanobody-Based CD19/CD22 Tandem Dual CAR-T Therapy for R/R B-ALL [Phase 1, Phase 2]
This clinical trial is evaluating a nanobody-based CD19/CD22 tandem dual CAR-T cell therapy for relapsed/refractory precursor B-cell lymphob…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: PK, PD, Safety and Immunogenicity of Spectrila in Adults With Acute B-cell Lymphoblastic Leukaemia [Phase 2]
Phase 2 study assessing PK, pharmacodynamics, safety and immunogenicity of Spectrila in adults with acute lymphoblastic leukemia (B-cell) ha…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant [Phase 1]
Phase 1 trial of intensity-modulated total marrow irradiation with fludarabine phosphate and melphalan for relapsed hematologic cancers unde…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO) [Phase 2]
A Phase 2 study evaluating a chemotherapy-free induction regimen for Philadelphia chromosome-positive acute lymphoblastic leukemia using ino…