Systemic Lupus Erythematosus
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Achievement of LLDAS5 in Patients With Systemic Lupus Erythematosus Treated With Anifrolumab.
An update from an AstraZeneca-sponsored trial in systemic lupus erythematosus notes achievement of LLDAS5 with anifrolumab. The study is cur…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Dose Response of Exercise for Arthritis Management [NA]
A University of South Carolina-led clinical trial is investigating the dose-response effects of exercise on arthritis management and related…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE) and Sjogren's Disease (SjD) [Phase 1]
Phase 1 trial update evaluating intravenous ABBV-319 in adults with systemic lupus erythematosus and Sjögren's syndrome, focusing on adverse…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus [Phase 3]
A Phase 3 clinical trial to evaluate the efficacy and safety of Dapirolizumab Pegol in participants with moderately to severely active syste…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Clinical Trial on the Efficacy and Safety of TQH3906 in the Treatment of Systemic Lupus Erythematosus [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy and safety of TQH3906 for systemic lupus erythematosus. The study is not yet recruiting …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants [Phase 2]
Phase 2 study to evaluate the efficacy, safety, and pharmacokinetics of obinutuzumab in adolescents with active Class III/IV lupus nephritis…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: PRV-3279-2a Trial in Systemic Lupus [Phase 2]
Provention Bio's PRV-3279-2a Phase 2 trial for systemic lupus erythematosus was terminated, with results posted on 2026-04-03.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of Cenerimod for systemic lupus erythematosus; the study is currently active but n…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease [EARLY_Phase 1]
An early-phase trial of allogeneic CD19/BCMA CAR-T therapy for B-cell–related autoimmune diseases is recruiting at The Children's Hospital o…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: To Evaluate the Efficacy and Safety of SG301 SC Injection in Systemic Lupus Erythematosus [Phase 2]
Phase 2 clinical trial update evaluating SG301 SC injection for systemic lupus erythematosus is currently recruiting to assess efficacy and …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus [Phase 3]
Phase 3 clinical trial evaluating the oral medicine Cenerimod for adults with systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of Lupus [Phase 1]
A Phase 1 clinical trial assessing safety, tolerability, drug levels and effects of BMS-986326 in adults with lupus, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004) [Phase 1]
This is a Phase 1 clinical trial evaluating MK-1045 in people with systemic lupus erythematosus or rheumatoid arthritis. The study is curren…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study of Intravenous CPTX2309 in Healthy Participants and Participants With Moderate to Severe Rheumatoid Arthritis (RA) or Systemic Lupus Erythematosus (SLE) [Phase 1]
Phase 1 clinical trial update for CPTX2309, an investigational therapy, evaluating safety in healthy participants and in individuals with rh…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: A Study to Continue the Administration of Deucravacitinib in Participants With Systemic Lupus Erythematosus (SLE) or Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) Who Have Completed Study IM011074 or Study IM011132 [Phase 4]
Phase 4 clinical trial update indicating that deucravacitinib is being studied in participants with systemic lupus erythematosus (SLE) or di…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus [Phase 2]
Phase 2 clinical trial update on Frexalimab (SAR441344) for systemic lupus erythematosus, highlighting ongoing assessment of efficacy and sa…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Descartes-08 for Patients With Systemic Lupus Erythematosus [Phase 2]
Descartes-08 is being tested in a Phase 2 trial for systemic lupus erythematosus, and the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE) [Phase 1]
Climb Bio, Inc. announced a Phase 1b clinical trial evaluating Budoprutug in adults with systemic lupus erythematosus, currently recruiting.
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CLINICAL_TRIALS withdrawal · 2026-03-27Clinical Trial Update: Pregnancy and Medically Assisted Conception in Rare Diseases
Clinical trial NCT02450396 on pregnancy and medically assisted conception in rare autoimmune diseases has been withdrawn.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment [Phase 3]
A Phase 3 clinical trial is recruiting to evaluate the efficacy and safety of Cenerimod in active lupus nephritis on top of standard therapy…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE) [Phase 1]
A Phase 1 study evaluating HB2198 in adults with systemic lupus erythematosus, including lupus nephritis, is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Therapeutic Drug Monitoring of Mycophenolate Mofetil in Lupus Nephritis [NA]
This ClinicalTrials.gov study evaluates therapeutic drug monitoring of mycophenolate mofetil in systemic lupus erythematosus and lupus nephr…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases [Phase 1]
Phase 1 clinical trial update on an allogeneic CD19/BCMA-targeted CAR-γδT cell therapy assessing safety and preliminary pharmacodynamics in …
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Respiratory Function, Physical Activity and Fatigue in SLE
This clinical trial update reports the completion of a study evaluating respiratory function, physical activity, and fatigue in people with …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases [EARLY_Phase 1]
An early phase 1 exploratory trial is assessing the safety and potential efficacy of anti-CD19/BCMA CAR-NK cell injections for refractory pe…