Systemic Lupus Erythematosus
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs） [Phase 1]
Phase 1 trial update showing that HN2301 is being studied for autoimmune diseases with ongoing recruitment, including systemic lupus erythem…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus [Phase 1]
A first-in-human Phase 1 trial is evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of RO7507062 in participants w…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Lupus Intervention for Fatigue Trial [NA]
A clinical trial update for NCT02653287 describes an intervention aimed at reducing fatigue in systemic lupus erythematosus. The study is cu…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Lupus Walking Intervention to Address Fatigue/Quality of Life [NA]
A completed clinical trial update focusing on a walking intervention to address fatigue and quality of life in systemic lupus erythematosus.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Anifrolumab Real-world Treatment Outcomes in Systemic Lupus Erythematosus
A real-world study evaluating the outcomes of anifrolumab for systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: NIS to Examine Disease Activity in SLE Patients Treated With Subcutaneous Anifrolumab in Routine Care
A non-interventional study (NIS) is recruiting to examine disease activity in systemic lupus erythematosus patients treated with subcutaneou…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus [Phase 1, Phase 2]
A Phase 1/2 open-label study evaluating the safety and efficacy of CABA-201 in active systemic lupus erythematosus (including lupus nephriti…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE [Phase 1, Phase 2]
This clinical trial update describes the study of AZD0120 in adults with refractory systemic lupus erythematosus, spanning Phase 1 and Phase…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: International Prospective Study on Adherence to Treatment in Patients With Active Systemic Lupus Erythematosus
International prospective study update assessing adherence to treatment in patients with active systemic lupus erythematosus.
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus [Phase 2]
This document reports an active Phase 2 placebo-controlled trial evaluating ESK-001 for active systemic lupus erythematosus.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: CHT105 for the Treatment of Refractory Lupus Nephritis [NA]
Clinical trial update for CHT105 evaluating its use in refractory lupus nephritis; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study of GC012F Injection in Subjects With Refractory Systemic Lupus Erythematosus [Phase 1, Phase 2]
This entry reports that a Phase 1/2 study evaluating GC012F injection for refractory systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease [Phase 1]
Phase 1 clinical trial update for ALLO-329, an allogeneic CAR T-cell therapy, in adults with autoimmune diseases including systemic lupus er…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of E6742 in Participants With Systemic Lupus Erythematosus [Phase 2]
A Phase 2 clinical trial evaluating E6742 for systemic lupus erythematosus is listed as not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Universal Anti-CD70 CAR-T (CHT101) Cell Therapy for Relapsed Refractory Systemic Lupus Erythematosus [EARLY_Phase 1]
Early-phase trial update for CHT101, a universal anti-CD70 CAR-T cell therapy for relapsed/refractory systemic lupus erythematosus; the stud…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus [Phase 3]
This update describes a Phase 3 clinical trial evaluating obinutuzumab for systemic lupus erythematosus, with study status currently active …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
Clinical trial update describing the development of a therapeutic endpoint for pediatric rheumatologic conditions. Recruitment is underway f…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus [Phase 2]
A Phase 2a multicenter randomized, double-blind, placebo-controlled study assessing the efficacy and safety of VENT-03 in adults with active…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants [Phase 3]
Phase 3 pediatric trial evaluating intravenous anifrolumab for systemic lupus erythematosus is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of KITE-363 in Participants With Refractory Autoimmune Diseases [Phase 1]
Phase 1 study evaluating KITE-363 in participants with refractory autoimmune diseases, currently enrolling by invitation, including systemic…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD [Phase 2]
This is a Phase 2 clinical trial assessing whether anifrolumab improves vascular risk markers in systemic lupus erythematosus; the study is …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2) [Phase 3]
A Phase 3 clinical trial evaluating Enpatoran for cutaneous lupus manifestations with or without systemic lupus erythematosus is currently r…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease [Phase 3]
A Phase 3 clinical trial evaluating enpatoran for cutaneous lupus manifestations in patients with or without systemic lupus erythematosus is…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Study of YKST02 Alone or in Combination With YK012 in Patients With Active or Refractory Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical trial evaluating YKST02 alone or in combination with YK012 for active or refractory systemic lupus erythematosus; the stu…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Study of Systemic Lupus Erythematosus
This clinical trial update indicates that a study evaluating systemic lupus erythematosus, sponsored by NIAMS, is currently recruiting parti…