Clinical Trial Update: Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE [Phase 3]

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Summary

A Phase 3 clinical trial evaluated the efficacy, safety, tolerability, and pharmacokinetics/pharmacodynamics of emapalumab in children and adults with macrophag…

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Diseases / indications

• Adult-onset Still Disease
• Hemophagocytic Lymphohistiocytosis
• Macrophage Activation Syndrome
• Systemic Juvenile Idiopathic Arthritis
• Systemic Lupus Erythematosus

Drugs mentioned

• GAMIFANT (emapalumab-lzsg)

Snippet

Sponsor: Swedish Orphan Biovitrum | Conditions: Macrophage Activation Syndrome, Secondary Hemophagocytic Lymphohistiocytosis | Phase 3 | Status: COMPLETED | Results posted: 2026-02-19