Systemic Lupus Erythematosus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Safety of PiggyBac Transposon CAR T-cells Targeting CD-19 in Refractory Lupus. [Phase 1]
This Phase 1 trial reports safety data for PiggyBac transposon–based CD-19 CAR T-cells in patients with refractory systemic lupus erythemato…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus [Phase 1, Phase 2]
This is an open-label Phase 1/2 trial to evaluate the safety, efficacy, and cellular kinetics of YTB323 in adults with severe, refractory sy…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: An Ascending Dose Study of PIT565 in Participants With Systemic Lupus Erythematosus (SLE). [Phase 1]
Phase 1 ascending-dose study of PIT565 in participants with systemic lupus erythematosus is currently recruiting to assess safety and tolera…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Long-Term Safety and Efficacy Study of Deucravacitinib in Participants With Systemic Lupus Erythematosus [Phase 2]
This Phase 2 long-term safety and efficacy study of deucravacitinib in systemic lupus erythematosus has completed data collection and posted…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Safety and Effectiveness of BENLYSTA (Belimumab) in Systemic Lupus Erythematosus (SLE) Registry
This clinical trial update reports on the safety and effectiveness of BENLYSTA (belimumab) in a systemic lupus erythematosus registry, with …
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: A Study of SHR-2173 in Participants With Systemic Lupus Erythematosus [Phase 2]
Phase 2 clinical trial evaluating SHR-2173 in participants with systemic lupus erythematosus; the study status is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Autoimmune Rheumatic Diseases [Phase 1]
Phase 1 clinical trial evaluating the safety and activity of SAR448501/DR-0201 in patients with autoimmune rheumatic diseases, including sys…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Identification of Modifiable Sleep-related Factors in Patients With Systemic Lupus Erythematosus.
A clinical trial is investigating modifiable sleep-related factors in patients with systemic lupus erythematosus to identify potential targe…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: SAPHNELO Systemic Lupus Erythematosus Japan Post-Marketing Surveillance (PMS)
Post-marketing surveillance update for SAPHNELO (anifrolumab) in systemic lupus erythematosus in Japan; the PMS is active and not recruiting…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: IASO-782 in Systemic Lupus Erythematosus [Phase 1]
A Phase 1 clinical trial evaluating IASO-782 for systemic lupus erythematosus is not yet recruiting, according to the trial record.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease [Phase 1]
Phase 1 trial update for Prulacabtagene Leucel (Prula-cel) in autoimmune diseases, with enrollment by invitation ongoing across indications …
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Characteristics and Disease Progression of Mixed Connective Tissue Disease and Systemic Lupus Erythematosus
This completed University of Miami study examined characteristics and disease progression in patients with mixed connective tissue disease a…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: The Anifrolumab PRIM Program
The document indicates that AstraZeneca's Anifrolumab PRIM Program for systemic lupus erythematosus is currently recruiting participants.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus [Phase 1]
This clinical trial update reports that CLN-978, a subcutaneously administered CD19-directed T cell engager, is being studied in subjects wi…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune Diseases
A clinico-biological collection study designed to investigate the pathophysiology of systemic autoimmune diseases, including systemic lupus …
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD) [Phase 1]
A Phase 1 clinical trial evaluating GSK5926371 in participants with B-cell driven autoimmune rheumatic diseases, including systemic lupus er…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Multicenter, Observational, Descriptive Study of the Diagnosis, Course and Treatment of Patients With SLE in Routine Practice in Kazakhstan: a Registry Study With Retrospective and Prospective Components.
A multicenter registry study in Kazakhstan to describe systemic lupus erythematosus activity, disease course, and treatment in routine pract…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis. [Phase 1]
A Phase 1 trial evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of AZD5492 in adults with systemic lupus erythem…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension). [Phase 3]
Phase 3 extension study to evaluate long-term safety of ianalumab in systemic lupus erythematosus; currently recruiting.
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Moderate to Severe Active SLE Clinical Research [EARLY_Phase 1]
This early-phase trial investigates the safety and potential efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) for moderate to se…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Clinical Study of EVM18001 in the Treatment of Refractory Autoimmune Diseases [NA]
A clinical trial evaluating EVM18001 for refractory autoimmune diseases is currently recruiting, including systemic lupus erythematosus, sys…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms. [Phase 2]
A Phase 2 study of PF-06823859 in adults with active lupus erythematosus with skin involvement has been terminated.
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: The Effect of Co-enzyme Q10 on the Clinical Outcome of Pediatric Patients With Systemic Lupus Erythematosus [Phase 2]
A completed Phase 2 clinical trial investigated the effect of Coenzyme Q10 on clinical outcomes in pediatric patients with systemic lupus er…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus [Phase 3]
Phase 3 clinical trial assessing adverse events and changes in disease activity with oral upadacitinib in adults with moderate to severe sys…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants [Phase 1]
Phase 1 clinical trial update for GSK4527363 including systemic lupus erythematosus and connective tissue disease-associated interstitial lu…