Pineoblastoma

• CLINICAL_TRIALS research · 2026-03-10
  Clinical Trial Update: Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) [Phase 1]

  This clinical trial update describes an ongoing Phase 1 study evaluating adoptive cellular therapy immunotherapy for several pediatric malig…

• CLINICAL_TRIALS research · 2026-02-27
  Clinical Trial Update: Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation [EARLY_Phase 1]

  This is a pediatric early-phase 1 trial update evaluating intrathecal topotecan with maintenance chemotherapy for high-risk embryonal centra…

• CLINICAL_TRIALS research · 2026-01-27
  Clinical Trial Update: GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults [Phase 1]

  Stanford is conducting a Phase 1 study of GPC2-CAR T cell therapy for relapsed or refractory medulloblastoma and related CNS embryonal tumor…

• CLINICAL_TRIALS research · 2025-06-17
  Clinical Trial Update: A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. [EARLY_Phase 1]

  An early-phase trial evaluating TP53 cDNA gene therapy combined with checkpoint inhibition and radiation in children with recurrent or refra…

• CLINICAL_TRIALS research · 2025-01-30
  Clinical Trial Update: International PPB/DICER1 Registry

  An international registry to collect data on tumors associated with DICER1 syndrome, including Pleuropulmonary Blastoma and related tumors, …

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