Clinical Trial Update: Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation [EARLY_Phase 1]

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Summary

This is a pediatric early-phase 1 trial update evaluating intrathecal topotecan with maintenance chemotherapy for high-risk embryonal central nervous system tum…

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Diseases / indications

• Atypical Teratoid Rhabdoid Tumor
• Cns Embryonal Tumor with Rhabdoid Features
• Embryonal Tumor with Abundant Neuropil and True Rosettes
• Embryonal Tumor with Multilayered Rosettes
• Ependymoblastoma
• Medulloblastoma
• Neuroblastoma
• Pineoblastoma

Drugs mentioned

• Topotecan (topotecan)

Snippet

Sponsor: C17 Council | Conditions: CNS Embryonal Tumor, CNS, Medulloblastoma | EARLY_Phase 1 | Status: RECRUITING