Patent Ductus Arteriosus
📧 Sign up to get email alerts when something new happens for Patent Ductus Arteriosus.
Sign up freeTop drugs studied for this disease
-
FDA approval · 2012-09-28FDA Approved: INDOMETHACIN — Original Application (Camber Pharmaceuticals, Inc.)
The FDA approved Camber Pharmaceuticals' indomethacin as an original ANDA (generic) application, making Indomethacin available as a generic …
-
CLINICAL_TRIALS trial_result · 2012-08-21Clinical Trial Update: Changes in Renal and Splanchnic Oxygenation During Ibuprofen Treatment for Patent Ductus Arterious
A completed clinical trial investigating how ibuprofen treatment for patent ductus arteriosus affects renal and splanchnic oxygenation.
-
CLINICAL_TRIALS withdrawal · 2012-06-07Clinical Trial Update: Second Course of Therapy for Resistant Patent Ductus Arteriosus (PDA) [Phase 2]
This update notes that a Phase 2 trial evaluating a second course of therapy for resistant patent ductus arteriosus has been withdrawn.
-
CLINICAL_TRIALS trial_result · 2012-05-24Clinical Trial Update: Safety and Effectiveness of the Device "Nit-Occlud® PDA-R" [Phase 2]
Phase 2 clinical trial results and safety assessment for the Nit-Occlud PDA-R device in closing patent ductus arteriosus in congenital heart…
-
CLINICAL_TRIALS trial_result · 2012-05-08Clinical Trial Update: Echocardiographically Guided Versus Standard Ibuprofen Treatment for Patent Ductus Arteriosus [Phase 3]
A Phase 3 trial comparing echocardiography-guided ibuprofen dosing with standard ibuprofen treatment for patent ductus arteriosus has comple…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2012-01-20Clinical Trial Update: Safety and Efficacy of Ibuprofen in Term Newborns With Patent Ductus Arteriosus (PDA) [NA]
A completed clinical trial evaluating the safety and efficacy of ibuprofen for treatment of patent ductus arteriosus in term newborns.
-
CLINICAL_TRIALS trial_result · 2011-09-20Clinical Trial Update: Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants [Phase 4]
Phase 4 CAST trial updating the use of Curosurf (poractant alfa) and Survanta (beractant) for respiratory distress syndrome in very prematur…
-
CLINICAL_TRIALS trial_result · 2011-08-09Clinical Trial Update: Efficacy and Safety of Oral Versus Intravenous Ibuprofen for PDA Treatment in ELBW Infants [NA]
A completed trial comparing oral versus intravenous ibuprofen for treating patent ductus arteriosus in extremely low birth weight infants, e…
-
CLINICAL_TRIALS research · 2011-07-22Clinical Trial Update: Oral Ibuprofen Prophylaxis for Patent Ductus Arterioses in Very Extremely Low Birth Weight Infants [NA]
A clinical trial update on using oral ibuprofen for prophylaxis of patent ductus arteriosus in extremely low birth weight infants; the curre…
-
CLINICAL_TRIALS other · 2011-07-21Clinical Trial Update: Ibuprofen vs. Continuous Indomethacin in the Treatment of PDA [Phase 3]
Phase 3 trial comparing ibuprofen with continuous indomethacin for patent ductus arteriosus has completed.
-
FDA approval · 2011-04-12FDA Approved: INDOMETHACIN — Original Application (XLCare Pharmaceuticals Inc.)
FDA approved the Indomethacin Original Application for XLCare Pharmaceuticals Inc., enabling a generic indomethacin product to reach the mar…
-
CLINICAL_TRIALS trial_result · 2010-11-19Clinical Trial Update: High-dose Ibuprofen for Patent Ductus Arteriosus (PDA) in Preterm Infant [Phase 2, Phase 3]
A Phase 2/3 trial evaluating high-dose ibuprofen for treating patent ductus arteriosus in preterm infants has completed.
-
CLINICAL_TRIALS research · 2010-09-14Clinical Trial Update: Timing of Closure of Patent Foramen Ovale Following Birth
Clinical trial update from Wolfson Medical Center about the timing of closure of patent foramen ovale and patent ductus arteriosus after bir…
-
CLINICAL_TRIALS trial_result · 2010-06-23Clinical Trial Update: Comparison of Oral and Intravenous Ibuprofen for PDA Treatment in Premature Infants [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing oral versus intravenous ibuprofen for treating patent ductus arteriosus in extremely premature infants,…
-
CLINICAL_TRIALS research · 2010-04-12Clinical Trial Update: Urine NT-proBNP Levels and Echocardiographic Findings in Very Low Birth Weight (VLBW) Infants
This clinical trial update reports urine NT-proBNP biomarker levels and echocardiographic findings in very low birth weight premature infant…
-
FDA approval · 2010-03-17FDA Approved: INDOMETHACIN — Original Application (Fresenius Kabi USA, LLC)
The FDA approved an original NDA for indomethacin from Fresenius Kabi USA, LLC. The approval covers indications for inflammatory and musculo…
-
CLINICAL_TRIALS trial_result · 2009-09-18Clinical Trial Update: Plasma N-terminal proBNP Concentrations and Patent Ductus Arteriosus in Preterm Babies
A completed clinical trial analyzed plasma N-terminal proBNP concentrations in preterm infants to investigate its relationship with patent d…
-
FDA approval · 2009-03-06FDA Approved: INDOMETHACIN — Original Application (KVK-Tech, Inc.)
FDA approved an original application for Indomethacin by KVK-Tech, Inc., establishing a generic version of indomethacin. The approval signif…
-
CLINICAL_TRIALS trial_result · 2008-06-04Clinical Trial Update: Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus [Phase 2]
A Phase 2 clinical trial compares two dosing protocols of indomethacin to treat patent ductus arteriosus in infants born at less than 28 wee…
-
CLINICAL_TRIALS trial_result · 2008-03-25Clinical Trial Update: Comparative Study of Efficacy and Safety of Oral Ibuprofen and Intravenous Ibuprofen in Closure of Patent Ductus Arteriosus in Very Low Birth Weight Infants [Phase 4]
This Phase 4 study compared the efficacy and safety of oral ibuprofen versus intravenous ibuprofen for closure of patent ductus arteriosus i…
-
CLINICAL_TRIALS trial_result · 2008-02-15Clinical Trial Update: Treating the Resistant Patent Ductus Arteriosus (PDA) [Phase 2]
Phase 2 clinical trial update evaluating treatment for resistant patent ductus arteriosus. The current status of the trial is unknown.
-
CLINICAL_TRIALS trial_result · 2007-09-14Clinical Trial Update: Plasma B-Type Natriuretic Peptide Concentrations in Preterm Infants < 28 Weeks
This clinical trial measured plasma B-type natriuretic peptide (BNP) concentrations in very preterm infants (<28 weeks) and has completed, e…
-
CLINICAL_TRIALS trial_result · 2007-02-27Clinical Trial Update: Safety and Efficacy Study of Ibuprofen l-Lysine Solution in Premature Infants for Treatment of PDA [Phase 3]
Phase 3 safety and efficacy study of ibuprofen l-Lysine solution for treating patent ductus arteriosus in premature infants has completed.
-
CLINICAL_TRIALS trial_result · 2006-09-19Clinical Trial Update: Ibuprofen and Renal Function in Premature Infants [Phase 4]
Phase 4 trial completed evaluating ibuprofen for patent ductus arteriosus closure in premature infants and its effects on renal function.
-
CLINICAL_TRIALS trial_result · 2006-06-26Clinical Trial Update: New Management Strategy of PDA for VLBW Preterm Infants [NA]
A clinical trial investigating a new management strategy for patent ductus arteriosus in very low birth weight preterm infants was terminate…