Patent Ductus Arteriosus
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
A pilot study update on NeoDoppler, a new ultrasound technology for continuous monitoring of cerebral circulation in neonates, currently rec…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: PREEMIE: Study for Treatment of PDA in Premature Infants [NA]
Clinical trial status update for the PREEMIE study evaluating treatment of patent ductus arteriosus in premature infants; the trial is activ…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Co-administration of Acetaminophen With Ibuprofen to Improve Duct-Related Outcomes in Extremely Premature Infants [Phase 2]
Phase 2 clinical trial evaluating co-administration of acetaminophen with ibuprofen to improve duct-related outcomes in extremely premature …
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes
Clinical trial update on early prediction of spontaneous patent ductus arteriosus closure and related outcomes in preterm infants.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: PDA for Kidneys Study
Clinical trial update indicates the PDA for Kidneys study is actively recruiting to investigate treatment for patent ductus arteriosus and c…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Research on the Individualized Treatment Strategy for Extremely Preterm Infants With hsPDA Based on Biomarkers and Targeted Delivery Systems
This clinical trial update describes a research study at Peking University Third Hospital investigating an individualized treatment strategy…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Relation Between Prostaglandin E2 Metabolite Levels and the Development of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Neonates
An ongoing Ain Shams University clinical trial examines whether prostaglandin E2 metabolite levels predict the development of hemodynamicall…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Trial [Phase 4]
An open randomized Phase 4 trial compares early hydrocortisone treatment to standard care for shock in extremely preterm neonates.
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Amplatzer Piccolo Occluder Japan Post-marketing Database Surveillance
This clinical trial update describes ongoing post-marketing database surveillance in Japan for the Amplatzer Piccolo Occluder used to treat …
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Management of the PDA Trial [Phase 3]
This is a Phase 3 clinical trial update for the management of patent ductus arteriosus in premature and newborn infants, with the study curr…
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Precision Dosing of Oral Ibuprofen for PDA, A Pilot RCT [Phase 2]
Phase 2 pilot randomized trial evaluating precision dosing of oral ibuprofen for treating patent ductus arteriosus in preterm infants is cur…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Dynamic Changes of Ductus Arteriosus in < 31 Weeks Preterm Infants: an Observational Study
This clinical trial update describes an observational study tracking dynamic changes of the ductus arteriosus in extremely preterm infants (…
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: Outcome of Transcatheter Closure of Patent Ductus Arteriosus in Pediatric Cardiology Unit in 3 Years Duration [NA]
This clinical trial entry describes a plan to evaluate transcatheter closure of patent ductus arteriosus in pediatric patients over a three-…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Study of Thoracic Ultrasound As a Response to the Closure of Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants
A recruiting clinical study evaluating thoracic ultrasound as a monitoring or response tool after closure of hemodynamically significant pat…
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CLINICAL_TRIALS research · 2018-07-30Clinical Trial Update: Alternative Paracetamol Treatments for the Neonate With a hsPDA [Phase 2, Phase 3]
Phase 2 and Phase 3 clinical trials are evaluating alternative paracetamol treatments to close hemodynamically significant patent ductus art…
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CLINICAL_TRIALS research · 2017-08-29Clinical Trial Update: Paracetamol Versus Ibuprofen for PDA Closure [Phase 4]
A Phase 4 clinical trial update comparing paracetamol and ibuprofen for closure of patent ductus arteriosus, with the current status not dis…
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CLINICAL_TRIALS research · 2017-07-25Clinical Trial Update: Laser Acupuncture and Pain Management in Preterm Infants Undergoing Patent Ductus Arteriosus Ligation [NA]
This clinical trial update reports on a completed study evaluating laser acupuncture for pain management in preterm infants undergoing paten…
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CLINICAL_TRIALS research · 2017-02-10Clinical Trial Update: NIRS in PDA VLBW Infants
This clinical trial update reports the completion of a study evaluating near-infrared spectroscopy (NIRS) in very low birth weight infants w…
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CLINICAL_TRIALS research · 2016-09-22Clinical Trial Update: International Experience in Timing And Choices for Ductal Closure in Patent Ductus Arteriosus:INTERPDA Trial
An international update on the INTERPDA trial examining timing and choices for closing the patent ductus arteriosus.
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CLINICAL_TRIALS research · 2015-11-17Clinical Trial Update: The Best Treatment Strategy: Surgical vs Pharmacological to Close the Ductus Arteriosus Persistent in Preterm Infants [Phase 2]
This clinical trial update discusses evaluating the best treatment strategy to close the patent ductus arteriosus in preterm infants, compar…
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CLINICAL_TRIALS research · 2015-08-19Clinical Trial Update: Hyperion™ International Registry Trial
Hyperion International Registry Trial sponsored by the European Cardiovascular Research Center is investigating atrial septal defects and pa…
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CLINICAL_TRIALS research · 2012-12-17Clinical Trial Update: Serum Level Measurement of Oral Paracetamol and Oral Ibuprofen for Patent Ductus Arteriosus Treatment in Preterm Infants [Phase 4]
Phase 4 clinical trial update examining serum levels of oral paracetamol (acetaminophen) and oral ibuprofen for treatment of patent ductus a…
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CLINICAL_TRIALS research · 2011-07-22Clinical Trial Update: Oral Ibuprofen Prophylaxis for Patent Ductus Arterioses in Very Extremely Low Birth Weight Infants [NA]
A clinical trial update on using oral ibuprofen for prophylaxis of patent ductus arteriosus in extremely low birth weight infants; the curre…
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CLINICAL_TRIALS research · 2010-09-14Clinical Trial Update: Timing of Closure of Patent Foramen Ovale Following Birth
Clinical trial update from Wolfson Medical Center about the timing of closure of patent foramen ovale and patent ductus arteriosus after bir…
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CLINICAL_TRIALS research · 2010-04-12Clinical Trial Update: Urine NT-proBNP Levels and Echocardiographic Findings in Very Low Birth Weight (VLBW) Infants
This clinical trial update reports urine NT-proBNP biomarker levels and echocardiographic findings in very low birth weight premature infant…