Patent Ductus Arteriosus
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2015-09-02Clinical Trial Update: Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature Babies [Phase 4]
A Phase 4 clinical trial comparing ibuprofen versus indomethacin for the treatment of patent ductus arteriosus in very preterm infants has b…
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CLINICAL_TRIALS research · 2015-08-19Clinical Trial Update: Hyperion™ International Registry Trial
Hyperion International Registry Trial sponsored by the European Cardiovascular Research Center is investigating atrial septal defects and pa…
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CLINICAL_TRIALS trial_result · 2015-06-26Clinical Trial Update: The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart Disease [Phase 3]
Phase 3 clinical trial update evaluating the pharmacology and hemodynamics of dexmedetomidine in children with congenital heart disease, wit…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP) [Phase 3]
Phase 3 trial of Indomethacin prophylaxis in preterm, very low birth weight infants (TIPP) has completed, evaluating prevention of patent du…
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FDA approval · 2015-03-09FDA Approved: EDEX — Supplemental Application (Endo USA, Inc.)
The FDA approved a supplemental application for EDEX (alprostadil) from Endo USA, Inc., indicating changes to the product’s labeling under N…
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CLINICAL_TRIALS withdrawal · 2015-01-26Clinical Trial Update: Brain, Gut and Kidney Blood Flow During Medical Closure of PDA
The clinical trial NCT00554307 evaluating brain, gut, and kidney blood flow during pharmacologic closure of patent ductus arteriosus has bee…
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Timing for the Medical Treatment of Patent Ductus Arteriosus in Preterm Infants
A completed clinical trial from the University of Utah examines when to start medical treatment for patent ductus arteriosus in preterm infa…
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FDA approval · 2014-10-16FDA Approved: INDOCIN — Supplemental Application (Zyla Life Sciences US LLC)
FDA approved a supplemental application for Indocin (indomethacin) submitted by Zyla Life Sciences US LLC.
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CLINICAL_TRIALS trial_result · 2014-07-18Clinical Trial Update: Closure Of Patent Ductus Arteriosus With the AMPLATZER Duct Occluder the AMPLATZER® Duct Occluder [NA]
A completed clinical trial evaluating the AMPLATZER Duct Occluder for closing patent ductus arteriosus (PDA) has posted results.
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FDA approval · 2014-06-09FDA Approved: PROSTIN VR PEDIATRIC — Supplemental Application (Pharmacia & Upjohn Company LLC)
The FDA approved a supplemental application for PROSTIN VR PEDIATRIC (alprostadil) from Pharmacia & Upjohn Company LLC.
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CLINICAL_TRIALS trial_result · 2014-04-11Clinical Trial Update: Pocket Echocardiography System (PES) for Detection of PDA in Neonates [NA]
This update reports the completion and posting of results for a clinical trial evaluating a Pocket Echocardiography System to detect Patent …
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FDA label_change · 2014-03-12FDA Approved: EDEX — Supplemental Application (Endo USA, Inc.)
FDA approved a supplemental application for EDEX (alprostadil) from Endo USA, Inc., resulting in changes to the product labeling.
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates [Phase 4]
A Phase 4 safety/efficacy trial evaluating optimized ibuprofen dosing for higher patent ductus arteriosus closure rates was TERMINATED.
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CLINICAL_TRIALS trial_result · 2014-01-03Clinical Trial Update: Patent Ductus Arteriosus (PDA) Screening Trial [NA]
The patent ductus arteriosus (PDA) screening trial has completed, with no results reported in the update.
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CLINICAL_TRIALS trial_result · 2013-12-16Clinical Trial Update: AMPLATZER Duct Occluder II Clinical Study [NA]
Clinical study of the AMPLATZER Duct Occluder II in patients with Patent Ductus Arteriosus; the trial is completed with results posted on 20…
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CLINICAL_TRIALS trial_result · 2013-12-13Clinical Trial Update: Management of Patent Ductus in Premature Infants [Phase 3]
Phase 3 clinical trial evaluating management of patent ductus arteriosus in premature infants has completed.
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CLINICAL_TRIALS trial_result · 2013-11-28Clinical Trial Update: Timing of PDA Closure and Respiratory Outcome in Premature Infants [NA]
A clinical trial evaluated the timing of patent ductus arteriosus closure and its effect on respiratory outcomes in premature infants. The s…
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CLINICAL_TRIALS trial_result · 2013-08-28Clinical Trial Update: Long Term Results of 450 Percutaneous Closures of PDA in a Single Center
This clinical trial report presents long-term outcomes of 450 percutaneous closures of patent ductus arteriosus performed at a single center…
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CLINICAL_TRIALS trial_result · 2013-07-04Clinical Trial Update: Do Elevated BNP Levels Predict Hemodynamically Significant PDAs
A completed clinical trial evaluating whether elevated BNP levels can predict hemodynamically significant patent ductus arteriosus.
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CLINICAL_TRIALS withdrawal · 2013-01-16Clinical Trial Update: Impact of Maternal-infant Therapeutics on Safety, Mortality, and Disability
A Duke University-sponsored clinical trial evaluating maternal-infant therapeutics for safety, mortality, and disability has been withdrawn;…
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CLINICAL_TRIALS trial_result · 2013-01-03Clinical Trial Update: Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants [NA]
This clinical trial evaluating indomethacin or ibuprofen for closing patent ductus arteriosus in extremely low birth weight infants has comp…
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CLINICAL_TRIALS trial_result · 2012-12-27Clinical Trial Update: Oral Paracetamol Versus Oral Ibuprofen in Management of Patent Ductus Arteriosus in Preterm Infants: A Randomised Controlled Trial [Phase 4]
A completed Phase 4 randomized trial compares oral paracetamol to oral ibuprofen for the management of patent ductus arteriosus in preterm i…
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CLINICAL_TRIALS trial_result · 2012-12-19Clinical Trial Update: Paracetamol and Patent Ductus Arteriosus (PDA) [Phase 2]
This update reports a Phase 2 clinical trial evaluating paracetamol for patent ductus arteriosus. The current trial status is unknown.
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CLINICAL_TRIALS research · 2012-12-17Clinical Trial Update: Serum Level Measurement of Oral Paracetamol and Oral Ibuprofen for Patent Ductus Arteriosus Treatment in Preterm Infants [Phase 4]
Phase 4 clinical trial update examining serum levels of oral paracetamol (acetaminophen) and oral ibuprofen for treatment of patent ductus a…
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CLINICAL_TRIALS trial_result · 2012-11-09Clinical Trial Update: Feeding During Ibuprofen or Indomethacin Treatment of Preterm Infants [NA]
A completed clinical trial evaluating feeding during ibuprofen or indomethacin treatment in preterm infants with patent ductus arteriosus.