Osteosarcoma
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CLINICAL_TRIALS research · 2015-05-12Clinical Trial Update: Biomarkers in Predicting Response to Chemotherapy in Samples From Young Patients With Osteosarcoma
This clinical trial update reports on biomarkers that may predict chemotherapy response in samples from young patients with osteosarcoma.
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CLINICAL_TRIALS research · 2015-05-06Clinical Trial Update: Studying DNA in Tumor Tissue Samples From Patients With Localized or Metastatic Osteosarcoma
Clinical trial studying DNA in tumor tissue from patients with localized or metastatic osteosarcoma has completed.
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CLINICAL_TRIALS trial_result · 2015-05-01Clinical Trial Update: Samarium Sm 153 and Stem Cell Transplant Followed By Radiation Therapy Patients With Osteosarcoma [Phase 2]
Phase 2 trial evaluating Samarium Sm-153 and stem cell transplant followed by radiation therapy in patients with osteosarcoma (sarcoma).
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Trial With Gemcitabine and Rapamycin in Second Line of Metastatic Osteosarcoma [Phase 2]
This update notes the completion of a Phase 2 trial evaluating the combination of gemcitabine and rapamycin as second-line therapy for metas…
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CLINICAL_TRIALS trial_result · 2015-04-15Clinical Trial Update: Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood [Phase 2]
Phase 2 trial of imatinib mesylate in relapsed or refractory pediatric solid tumors has been completed.
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CLINICAL_TRIALS trial_result · 2015-03-31Clinical Trial Update: Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma [Phase 2]
Phase 2 trial evaluating cixutumumab with temsirolimus in pediatric patients with recurrent or refractory sarcomas has been completed with r…
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors [Phase 2]
Phase 2 trial results for cixutumumab in relapsed or refractory solid tumors across multiple sarcomas and pediatric cancers.
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: Inhaled Sargramostim in Treating Patients With First Pulmonary (Lung) Recurrence of Osteosarcoma [Phase 2]
A Phase 2 trial tested inhaled sargramostim for patients with first pulmonary recurrence of osteosarcoma. The study has completed and result…
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CLINICAL_TRIALS trial_result · 2015-02-27Clinical Trial Update: Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumors [Phase 1]
This dose-escalation Phase 1 trial evaluated the safety and tolerability of combining Sorafenib with Irinotecan in pediatric patients with s…
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CLINICAL_TRIALS trial_result · 2015-02-13Clinical Trial Update: Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED) [Phase 2]
This update reports the completion of a Phase 2 trial of ridaforolimus (AP23573/MK-8669), an mTOR inhibitor, in patients with advanced sarco…
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Huntsman Biopsy Study
The Huntsman Biopsy Study (NCT00615329) has been terminated according to the latest clinical trial status update.
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Ixabepilone in Treating Young Patients With Refractory Solid Tumors [Phase 2]
Phase 2 trial update on ixabepilone in young patients with refractory solid tumors. The study status is completed.
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CLINICAL_TRIALS trial_result · 2014-10-02Clinical Trial Update: Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung [Phase 2]
Phase 2 study evaluating REOLYSIN (pelareorep) for bone and soft tissue sarcomas metastatic to the lung has been completed, assessing safety…
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CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma [Phase 2]
Phase 2 trial of high-dose methotrexate with leucovorin rescue, with or without glucarpidase, in osteosarcoma was terminated; results were p…
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CLINICAL_TRIALS trial_result · 2014-09-10Clinical Trial Update: Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy [NA]
This clinical trial update reports the termination of a study in osteosarcoma evaluating doxorubicin with cisplatin, high-dose methotrexate,…
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CLINICAL_TRIALS research · 2014-09-03Clinical Trial Update: A Study of Endostar Combined With Chemotherapy for Treatment of Osteosarcoma [Phase 2]
A Phase 2 clinical trial is evaluating Endostar in combination with chemotherapy for osteosarcoma; current status is unknown.
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CLINICAL_TRIALS trial_result · 2014-08-05Clinical Trial Update: Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma [Phase 3]
A Phase 3 trial evaluating adding dexrazoxane to standard chemotherapy for newly diagnosed nonmetastatic osteosarcoma has completed. The stu…
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CLINICAL_TRIALS trial_result · 2014-08-04Clinical Trial Update: A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma [Phase 2]
Phase 2 trial assessing bevacizumab in combination with chemotherapy for osteosarcoma and malignant fibrous histiocytoma of bone has complet…
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CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma [Phase 1]
Phase 1 study evaluating zoledronic acid added to combination chemotherapy for newly diagnosed metastatic osteosarcoma; results have been po…
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CLINICAL_TRIALS trial_result · 2014-07-03Clinical Trial Update: Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze [Phase 1]
Open-label pharmacokinetic study of leucovorin in patients receiving high-dose methotrexate, with or without Voraxaze, completed Phase 1.
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CLINICAL_TRIALS trial_result · 2014-05-14Clinical Trial Update: Mifamurtide (L-MTP-PE) for High-Risk Osteosarcoma
The entry reports the completion of a clinical trial evaluating mifamurtide (L-MTP-PE) for high-risk osteosarcoma, summarizing outcomes for …
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CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: Eltrombopag for the Prevention of Chemotherapy Induced Thrombocytopenia [Phase 1]
Phase 1 trial of eltrombopag for preventing chemotherapy-induced thrombocytopenia in soft tissue sarcoma and osteosarcoma has been terminate…
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CLINICAL_TRIALS trial_result · 2014-03-28Clinical Trial Update: A Clinical Trial on Efficacy and Safety for Lobaplatin and Gemcitabine in Combination With Docetaxel in the Second-line Treatments on Advanced Osteosarcoma [Phase 2, Phase 3]
This clinical trial update describes a Phase 2/3 study evaluating the combination of lobaplatin and gemcitabine with docetaxel for second-li…
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CLINICAL_TRIALS trial_result · 2014-03-17Clinical Trial Update: Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07) [Phase 2]
Phase 2 clinical trial evaluating sorafenib in patients with soft tissue sarcomas, including metastatic and recurrent subtypes; results were…
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CLINICAL_TRIALS trial_result · 2014-01-30Clinical Trial Update: Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery [Phase 2]
Phase 2 trial results for Therapeutic Angiotensin-(1-7) in patients with unresectable metastatic sarcoma have results posted.