Osteosarcoma
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing Sarcoma [NA]
The update indicates that a Vanderbilt-Ingram Cancer Center trial evaluating quantitative imaging biomarkers of treatment response in osteos…
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CLINICAL_TRIALS trial_result · 2017-03-13Clinical Trial Update: Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic Osteosarcoma [Phase 2]
A Phase 2 clinical trial is evaluating metronomic chemotherapy for metastatic osteosarcoma, with the current status listed as UNKNOWN.
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FDA approval · 2017-03-07FDA Approved: METHOTREXATE — Supplemental Application (Fresenius Kabi USA, LLC)
The FDA approved a supplemental application for METHOTREXATE SODIUM from Fresenius Kabi USA, LLC.
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Surveillance Study of Patients With Newly Diagnosed Osteosarcoma
Terminated surveillance study of patients with newly diagnosed osteosarcoma. No results are reported in this update.
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CLINICAL_TRIALS trial_result · 2016-12-23Clinical Trial Update: Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma [Phase 1]
A Phase 1 study of temsirolimus with valproic acid in children with relapsed neuroblastoma, osteosarcoma, soft tissue sarcoma, or brain tumo…
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FDA approval · 2016-12-20FDA Approved: TREXALL — Supplemental Application (Teva Women's Health, Inc.)
FDA approved a supplemental application for TREXALL (methotrexate) from Teva Women's Health, Inc.
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: European Study in Bone Sarcoma Patients Over 40 Years
The European study of spindle cell sarcoma of bone and osteosarcoma in patients over 40 has completed.
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CLINICAL_TRIALS research · 2016-11-01Clinical Trial Update: Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma [Phase 4]
A Phase 4 clinical trial evaluating lithium carbonate in combination with neo-adjuvant chemotherapy for osteosarcoma; current status is not …
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CLINICAL_TRIALS trial_result · 2016-09-05Clinical Trial Update: A Retrospective Non-intervention Study to Characterize FOlate Rescue Treatment in Osteosarcoma Patients Treated With HDMTX
This is a completed retrospective non-interventional study by Isofol Medical AB to characterize folate rescue treatment in osteosarcoma pati…
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FDA approval · 2016-06-16FDA Approved: LEVOLEUCOVORIN — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved Hikma Pharmaceuticals USA Inc.'s levoleucovorin as an Original Application generic; levoleucovorin is used in cancer regimens w…
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CLINICAL_TRIALS research · 2016-05-19Clinical Trial Update: Study of Blood Samples From Patients With Osteosarcoma
A completed study sponsored by the Children's Oncology Group analyzes blood samples from patients with osteosarcoma to study biomarkers.
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas
A completed study evaluating biomarker expression in tissue samples from patients with osteosarcoma, including localized, metastatic, and re…
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: DNA Biomarkers in Samples From Patients With Osteosarcoma and Healthy Volunteers
This clinical trial update reports on a completed study examining DNA biomarkers in samples from osteosarcoma patients and healthy volunteer…
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CLINICAL_TRIALS trial_result · 2016-03-23Clinical Trial Update: Development of Indices Predicting Response to Pre-operative Chemotherapy in Osteosarcoma Patients
A completed clinical trial investigated indices that may predict how osteosarcoma patients respond to pre-operative chemotherapy. The study …
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CLINICAL_TRIALS research · 2016-03-08Clinical Trial Update: Genetic Biomarkers in Tissue Samples From Patients With Osteosarcoma
The Children's Oncology Group completed a study examining genetic biomarkers in tissue samples from patients with osteosarcoma. The aim was …
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CLINICAL_TRIALS research · 2016-02-11Clinical Trial Update: Prospective Clinical Trial Evaluating Metronomic Chemotherapy in Patients With High-grade, Operable, Non-metastatic Osteosarcoma of the Extremity [Phase 2]
Phase 2 prospective clinical trial evaluating metronomic chemotherapy in patients with high-grade, operable, non-metastatic osteosarcoma of …
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: Phase II Study of Chemotherapy and Pamidronate for the Treatment of Newly Diagnosed Osteosarcoma [Phase 2]
Phase II clinical trial evaluating chemotherapy plus pamidronate for newly diagnosed osteosarcoma completed; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: A Clinical Research on the Relation of Blood Drug Concentration and Calcium Folinate Rescued in High-dose MTX Therapy [NA]
This clinical trial update examines the relationship between blood methotrexate concentrations and calcium folinate rescue during high-dose …
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CLINICAL_TRIALS trial_result · 2015-12-11Clinical Trial Update: A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720) [Phase 2]
Phase 2 study of robatumumab in relapsed osteosarcoma or Ewing's sarcoma was terminated; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy [NA]
Completed clinical trial evaluating the effects of preoperative physical therapy in patients with lower extremity bone sarcomas; results are…
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CLINICAL_TRIALS research · 2015-08-21Clinical Trial Update: Long Term Neurotoxic Effects of Chemotherapy in Survivors of Bone and Soft Tissue Sarcomas. A Retrospective Study [NA]
A retrospective study evaluating long-term neurotoxic effects of chemotherapy in survivors of bone and soft tissue sarcomas.
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CLINICAL_TRIALS trial_result · 2015-07-30Clinical Trial Update: Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma [Phase 2]
Phase 2 trial evaluating the combination of temsirolimus and cixutumumab in locally advanced, metastatic, or recurrent soft tissue sarcoma a…
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma [Phase 2]
A completed Phase II open-label, non-randomized study evaluating the combination of sorafenib and everolimus in relapsed or non-resectable o…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma [Phase 2]
A Phase 2 trial evaluating chemotherapy before and after surgery for osteosarcoma was terminated, with limited details provided.
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CLINICAL_TRIALS trial_result · 2015-06-04Clinical Trial Update: Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays? [Phase 2]
Phase 2 trial evaluating glucarpidase after methotrexate in bone sarcomas was terminated; the update discusses whether this approach could r…