Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Aerosolized Aldesleukin in Treating Patients With Lung Metastases [Phase 1]
Phase 1 study evaluating aerosolized aldesleukin (interleukin-2) in patients with cancers that have metastasized to the lung, including mela…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Oleclumab and Durvalumab for the Treatment of Recurrent, Refractory, or Metastatic Sarcoma [Phase 2]
Phase 2 clinical trial update of the combination of oleclumab and durvalumab for recurrent, refractory, or metastatic sarcoma, including ang…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) [Phase 2]
Phase 2 update from the Pediatric MATCH trial describes targeted therapies matched to tumor genetics in pediatric patients with relapsed or …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma [Phase 2]
A Phase 2 trial evaluating trastuzumab deruxtecan for HER2-positive newly diagnosed or recurrent osteosarcoma has been suspended.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Study of Azenosertib (ZN-c3) in Combination With Gemcitabine in Subjects With Osteosarcoma [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating Azenosertib (ZN-c3) in combination with gemcitabine in patie…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma [Phase 2]
A Phase 2 trial evaluating maintenance cabozantinib with best supportive care versus best supportive care alone in children and adolescents …
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating IDH1-mutant tumors for response to ivosidenib; results for recurrent and refractory solid tumors, l…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: Olaparib With Ceralasertib in Recurrent Osteosarcoma [Phase 2]
Phase 2 trial evaluating the combination of olaparib and ceralasertib in recurrent osteosarcoma; the study is currently active but not recru…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma [Phase 1]
Phase 1 clinical trial evaluating nivolumab alone or with azacitidine in patients with recurrent, resectable osteosarcoma. The study is curr…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma [Phase 1]
Phase 1 trial sponsored by the National Cancer Institute evaluated the combination of magrolimab and dinutuximab in pediatric patients with …
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma [Phase 2]
Phase 2 trial update for eflornithine (DFMO) in osteosarcoma and Ewing sarcoma (including metastatic disease) indicates the study is not yet…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Glucarpidase After High-Dose Methotrexate in Patients With Osteosarcoma [EARLY_Phase 1]
This document provides an update on a Phase 1 trial evaluating glucarpidase after high-dose methotrexate in osteosarcoma patients.
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluated intra-arterial cisplatin plus rh-endostatin with systemic chemotherapy in osteosarcoma.
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: TQB2928 Injection Combined Anlotinib Hydrochloride Capsule in Recurrent/Metastatic Osteosarcoma and Other Solid Tumors [Phase 1]
Phase 1 trial of TQB2928 injection combined with Anlotinib hydrochloride capsule for recurrent/metastatic osteosarcoma and other solid tumor…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma [Phase 2]
A Phase 2 trial of nab-paclitaxel plus gemcitabine for recurrent or refractory sarcoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer [Phase 1, Phase 2]
This document details an ongoing Phase 1/2 clinical trial evaluating cobolimab in combination with dostarlimab in pediatric and young adult …
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating selpercatinib for patients with activating RET gene alterations across adv…
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, The GD2-CAR PERSIST Trial [Phase 1]
Phase 1 GD2-targeted CAR-T cell therapy (GD2CART) for recurrent/refractory neuroblastoma and osteosarcoma has a suspended status as of the u…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating larotrectinib in patients with NTRK gene fusions has posted results; the study remains active but n…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer [Phase 1]
Phase 1 trial update of PeptiCRAd-1 reports safety signals and anti-tumor activity across multiple cancers; trial status is ACTIVE_NOT_RECRU…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma [Phase 1]
Phase 1 trial evaluating metronomic chemotherapy in patients with advanced solid tumors with bone metastases and pretreated osteosarcoma. Re…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
Phase 2 pediatric MATCH trial results for Tipifarnib in HRAS-altered solid tumors and histiocytic disorders; the study has posted results an…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Quality of Life of Patients With Bone Tumor of the Lower Limbs Treated With Salvage Surgery
This completed clinical trial evaluates quality of life in patients with lower-limb bone tumors treated with salvage surgery.
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors [Phase 2]
Phase 2 trial update of haploidentical transplantation with donor natural killer cells for solid tumors; the study was terminated and result…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: B7-H3 NIR Imaging for Osteosarcoma Surgery [Phase 1, Phase 2]
Clinical trial update for a B7-H3-targeted near-infrared imaging probe to assist osteosarcoma surgery, spanning Phase 1 and Phase 2 and curr…