Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Methionine PET/CT Studies In Patients With Cancer [Phase 2]
Phase 2 methionine-based PET/CT imaging studies in patients with various cancers; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma [Phase 2]
Phase 2 clinical trial evaluating the efficacy of B7-H3 CAR T cells given after upfront MAP chemotherapy in newly diagnosed high-risk pediat…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma [NA]
An update on a clinical trial evaluating adaptive proton therapy for pediatric solid tumors and Hodgkin lymphoma. The trial is currently not…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma [Phase 1]
Phase 1 clinical trial update for iC9-GD2-CAR-VZV-CTLs in GD2-positive osteosarcoma and neuroblastoma; the study is currently active but not…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Aerosolized Aldesleukin in Treating Patients With Lung Metastases [Phase 1]
Phase 1 study evaluating aerosolized aldesleukin (interleukin-2) in patients with cancers that have metastasized to the lung, including mela…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas
ClinicalTrials.gov entry indicates recruitment for a study assessing healing and functional outcomes after reconstruction surgery for bone s…
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CLINICAL_TRIALS other · 2026-04-17Clinical Trial Update: Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study [Phase 2]
Phase 2 TACOS trial investigates atezolizumab with cabozantinib for recurrent or metastatic osteosarcoma in adolescents and young adults; re…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Agnostic Therapy in Rare Solid Tumors [Phase 2]
A Phase 2 trial of an agnostic therapy for multiple rare solid tumors is currently recruiting. The study lists a broad set of tumor types ac…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma [Phase 2, Phase 3]
A phase 2/3 clinical trial is evaluating the addition of cabozantinib to chemotherapy for newly diagnosed osteosarcoma, with recruitment cur…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Oleclumab and Durvalumab for the Treatment of Recurrent, Refractory, or Metastatic Sarcoma [Phase 2]
Phase 2 clinical trial update of the combination of oleclumab and durvalumab for recurrent, refractory, or metastatic sarcoma, including ang…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) [Phase 1]
Phase 1 clinical trial update for a B7-H3–targeted autologous CAR-T cell therapy (3CAR) in pediatric solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Musculoskeletal Cancers Remote Monitoring and Care [NA]
The clinical trial 'Musculoskeletal Cancers Remote Monitoring and Care' is currently recruiting and targets osteosarcoma and bone metastases…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) [Phase 2]
Phase 2 update from the Pediatric MATCH trial describes targeted therapies matched to tumor genetics in pediatric patients with relapsed or …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Lutathera (177Lu-DOTATATE) in combination with Olaparib for somatostatin receptor–expressing recurrent…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas [Phase 1, Phase 2]
Clinical trial update reports ongoing Phase 1/Phase 2 testing of eflornithine (DFMO) with AMXT 1501 for neuroblastoma, CNS tumors, and sarco…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial) [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating ensartinib for patients with relapsed or refractory ALK- or ROS1-genomic a…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma [Phase 2]
A Phase 2 trial evaluating trastuzumab deruxtecan for HER2-positive newly diagnosed or recurrent osteosarcoma has been suspended.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Study of HS-20093 Versus Gemcitabine in Combination With Docetaxel in Treatment of Osteosarcoma After Previous Second-line Treatment Failure [Phase 3]
Phase 3 trial comparing HS-20093 to Gemcitabine plus Docetaxel for osteosarcoma after second-line failure. The study is currently active but…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors [Phase 1, Phase 2]
Clinical trial evaluating silmitasertib (CX-4945) in combination with chemotherapy for relapsed or refractory solid tumors; Phase 1 and Phas…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults [NA]
Overview of the my.naviGATE guide for after-treatment effects in adolescents and young adults with sarcoma and related cancers; the study is…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Study of Azenosertib (ZN-c3) in Combination With Gemcitabine in Subjects With Osteosarcoma [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating Azenosertib (ZN-c3) in combination with gemcitabine in patie…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma [Phase 2]
A Phase 2 trial evaluating maintenance cabozantinib with best supportive care versus best supportive care alone in children and adolescents …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma [Phase 1]
Phase 1 clinical trial evaluating GD2-targeted CAR T-cells engineered with IL-15 and inducible caspase-9 for relapsed/refractory neuroblasto…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating IDH1-mutant tumors for response to ivosidenib; results for recurrent and refractory solid tumors, l…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Regorafenib in Patients With Refractory Primary Bone Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating regorafenib in patients with refractory primary bone tumors, including osteosarcoma and Ewing sarcoma …