Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Methionine PET/CT Studies In Patients With Cancer [Phase 2]
Phase 2 methionine-based PET/CT imaging studies in patients with various cancers; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma [Phase 2]
Phase 2 clinical trial evaluating the efficacy of B7-H3 CAR T cells given after upfront MAP chemotherapy in newly diagnosed high-risk pediat…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma [NA]
An update on a clinical trial evaluating adaptive proton therapy for pediatric solid tumors and Hodgkin lymphoma. The trial is currently not…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma [Phase 1]
Phase 1 clinical trial update for iC9-GD2-CAR-VZV-CTLs in GD2-positive osteosarcoma and neuroblastoma; the study is currently active but not…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas
ClinicalTrials.gov entry indicates recruitment for a study assessing healing and functional outcomes after reconstruction surgery for bone s…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Agnostic Therapy in Rare Solid Tumors [Phase 2]
A Phase 2 trial of an agnostic therapy for multiple rare solid tumors is currently recruiting. The study lists a broad set of tumor types ac…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma [Phase 2, Phase 3]
A phase 2/3 clinical trial is evaluating the addition of cabozantinib to chemotherapy for newly diagnosed osteosarcoma, with recruitment cur…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR) [Phase 1]
Phase 1 clinical trial update for a B7-H3–targeted autologous CAR-T cell therapy (3CAR) in pediatric solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Musculoskeletal Cancers Remote Monitoring and Care [NA]
The clinical trial 'Musculoskeletal Cancers Remote Monitoring and Care' is currently recruiting and targets osteosarcoma and bone metastases…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Lutathera (177Lu-DOTATATE) in combination with Olaparib for somatostatin receptor–expressing recurrent…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas [Phase 1, Phase 2]
Clinical trial update reports ongoing Phase 1/Phase 2 testing of eflornithine (DFMO) with AMXT 1501 for neuroblastoma, CNS tumors, and sarco…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial) [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating ensartinib for patients with relapsed or refractory ALK- or ROS1-genomic a…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Study of HS-20093 Versus Gemcitabine in Combination With Docetaxel in Treatment of Osteosarcoma After Previous Second-line Treatment Failure [Phase 3]
Phase 3 trial comparing HS-20093 to Gemcitabine plus Docetaxel for osteosarcoma after second-line failure. The study is currently active but…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors [Phase 1, Phase 2]
Clinical trial evaluating silmitasertib (CX-4945) in combination with chemotherapy for relapsed or refractory solid tumors; Phase 1 and Phas…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults [NA]
Overview of the my.naviGATE guide for after-treatment effects in adolescents and young adults with sarcoma and related cancers; the study is…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma [Phase 1]
Phase 1 clinical trial evaluating GD2-targeted CAR T-cells engineered with IL-15 and inducible caspase-9 for relapsed/refractory neuroblasto…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Regorafenib in Patients With Refractory Primary Bone Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating regorafenib in patients with refractory primary bone tumors, including osteosarcoma and Ewing sarcoma …
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas [Phase 1]
Phase 1 dose-escalation study of CLR-131 in children with relapsed or refractory malignant tumors, including neuroblastoma and sarcomas, cur…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating apatinib in combination with liposomal irinotecan for refractory or metastatic osteosarcoma; the st…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma [Phase 2]
Phase 2 clinical trial evaluating the combination of gefitinib, trametinib, disulfiram, and sunitinib with standard chemotherapy for osteosa…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Upfront Surgical Resection for Osteosarcoma
An ongoing clinical study at Montefiore Medical Center is evaluating upfront surgical resection for osteosarcoma and is currently recruiting…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast
Expanded access (compassionate use) for the DNG64-CAR-V cell therapy in patients with advanced pancreatic cancer, various sarcoma subtypes, …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma [Phase 1, Phase 2]
A phase 1/2 study evaluating CAR.70-engineered IL-15-transduced cord blood-derived NK cells with lymphodepleting chemotherapy for advanced r…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Liposomal Irinotecan, Vincristine, Temozolomide, and Anlotinib for R/R Pediatric Solid Tumors [Phase 2]
This clinical trial update outlines a Phase 2 study evaluating a combination of liposomal irinotecan, vincristine, temozolomide, and anlotin…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma [Phase 1]
Phase 1 clinical trial evaluating atezolizumab in combination with SBRT and surgery for relapsed osteosarcoma (including pulmonary recurrenc…