Osteosarcoma

CLINICAL_TRIALS trial_result · 2023-09-08

Clinical Trial Update: ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer [Phase 2]

Phase 2 trial of ADI-PEG 20 in combination with gemcitabine and docetaxel for soft tissue sarcoma, osteosarcoma, Ewing's sarcoma, and small …

CLINICAL_TRIALS trial_result · 2023-08-14

Clinical Trial Update: Indo-cyanine Green (ICG) in Paediatric Oncology MIS [Phase 4]

Phase 4 trial update on using Indo-cyanine Green (ICG) in pediatric oncology, with completed status.

CLINICAL_TRIALS trial_result · 2023-08-07

Clinical Trial Update: A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma [Phase 2]

This Phase 2 trial assessed whether adding lenvatinib to Ifosfamide and Etoposide improves outcomes for children, adolescents, and young adu…

CLINICAL_TRIALS trial_result · 2023-07-07

Clinical Trial Update: M6620 (VX-970) in Selected Solid Tumors [Phase 2]

Phase 2 trial of M6620 (VX-970) in selected solid tumors completed; results posted in 2023.

CLINICAL_TRIALS trial_result · 2023-06-22

Clinical Trial Update: Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancers [Phase 1, Phase 2]

Phase 1/2 trial investigating Hu3F8-BsAb for relapsed/refractory neuroblastoma and osteosarcoma terminated with posted results.

CLINICAL_TRIALS trial_result · 2023-06-07

Clinical Trial Update: Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma [Phase 3]

A Phase 3 trial evaluating combination chemotherapy, PEG-interferon alfa-2b, and surgery for localized and metastatic osteosarcoma has compl…

CLINICAL_TRIALS trial_result · 2023-04-12

Clinical Trial Update: Surufatinib in Patients With Osteosarcoma and Soft Tissue Sarcoma [Phase 2]

A Phase 2 clinical trial update for surufatinib in patients with sarcoma including osteosarcoma and soft tissue sarcoma.

CLINICAL_TRIALS trial_result · 2023-01-10

Clinical Trial Update: Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas [Phase 1, Phase 2]

Phase 1/2 trial evaluating nivolumab with or without ipilimumab in younger patients with recurrent or refractory solid tumors or sarcomas; c…

CLINICAL_TRIALS trial_result · 2022-11-28

Clinical Trial Update: Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors [Phase 2]

A Phase 2 clinical trial evaluating cabozantinib-s-maleate in pediatric patients with recurrent, refractory, or newly diagnosed sarcomas, Wi…

CLINICAL_TRIALS trial_result · 2022-04-26

Clinical Trial Update: Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors [Phase 1, Phase 2]

Pepinemab was studied in a pediatric Phase 1/2 trial for recurrent, relapsed, or refractory solid tumors, including osteosarcoma. Results we…

CLINICAL_TRIALS trial_result · 2021-10-28

Clinical Trial Update: Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma [Phase 3]

A Phase 3 trial evaluating outpatient administration of high-dose methotrexate in patients with osteosarcoma has completed enrollment with r…

CLINICAL_TRIALS trial_result · 2021-09-16

Clinical Trial Update: A Phase II Trial of Avelumab in Patients With Recurrent or Progressive Osteosarcoma [Phase 2]

This update reports results from a Phase II trial of the PD-L1 inhibitor avelumab in patients with recurrent or progressive osteosarcoma; th…

CLINICAL_TRIALS trial_result · 2021-05-14

Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of ALMB-0168 in Patients With Osteosarcoma [Phase 1, Phase 2]

A study evaluating the safety and efficacy of ALMB-0168 in osteosarcoma across Phase 1 and Phase 2 is listed, with status currently UNKNOWN.

CLINICAL_TRIALS trial_result · 2021-05-07

Clinical Trial Update: Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma [Phase 2]

Phase 2 trial update of dinutuximab with sargramostim in recurrent osteosarcoma has completed enrollment with results posted in 2021.

CLINICAL_TRIALS trial_result · 2021-04-30

Clinical Trial Update: Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors [Phase 1, Phase 2]

Phase 1/2 trial evaluating stereotactic body radiotherapy (SBRT) for pulmonary metastases in several pediatric and young adult sarcoma-relat…

CLINICAL_TRIALS trial_result · 2021-02-21

Clinical Trial Update: Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma [Phase 2]

Phase 2 clinical trial evaluating denosumab in patients with recurrent or refractory osteosarcoma has completed with results posted.

CLINICAL_TRIALS trial_result · 2021-02-02

Clinical Trial Update: Phase I Dose Escalation of Monthly Intravenous Ra-223 Dichloride in Osteosarcoma [Phase 1, Phase 2]

Phase I dose-escalation trial of monthly intravenous Ra-223 dichloride in sarcoma (osteosarcoma) completed with results posted.

CLINICAL_TRIALS trial_result · 2020-10-29

Clinical Trial Update: Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer [Phase 3]

Phase 3 trial comparing fixed versus flexible dosing of filgrastim to speed bone marrow recovery after chemotherapy in children; the study i…

CLINICAL_TRIALS trial_result · 2020-09-17

Clinical Trial Update: Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma [Phase 1, Phase 2]

Phase 1/2 trial of lenvatinib in pediatric/adolescent and young adult patients with refractory or relapsed solid malignancies and osteosarco…

CLINICAL_TRIALS trial_result · 2020-09-04

Clinical Trial Update: Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma [Phase 2]

Phase 2 clinical trial update evaluating Cabozantinib S-malate in patients with relapsed or unresectable metastatic osteosarcoma or Ewing sa…

CLINICAL_TRIALS trial_result · 2020-08-10

Clinical Trial Update: Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas [Phase 2]

Phase 2 trial evaluating pazopanib hydrochloride combined with topotecan hydrochloride in adults with metastatic or recurrent soft tissue an…

CLINICAL_TRIALS trial_result · 2020-05-19

Clinical Trial Update: Apatinib Plus Anti-PD1 Therapy for Advanced Osteosarcoma [Phase 2]

Phase 2 trial update evaluating apatinib plus anti-PD1 therapy in advanced osteosarcoma has completed, reporting measures such as progressio…

CLINICAL_TRIALS trial_result · 2020-05-19

Clinical Trial Update: Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma [Phase 2]

Phase 2 trial comparing MAPI+camrelizumab, API+apatinib, and MAPI monotherapy in patients with poor response to preoperative chemotherapy fo…

CLINICAL_TRIALS trial_result · 2020-04-29

Clinical Trial Update: Study of ZKAB001 for Maintenance Therapy in Patients With High-grade Osteosarcoma After Adjuvant Chemotherapy [Phase 3]

A Phase 3 clinical trial evaluating ZKAB001 as maintenance therapy after adjuvant chemotherapy in patients with high-grade osteosarcoma.

CLINICAL_TRIALS trial_result · 2020-03-30

Clinical Trial Update: Phase II Clinical Trial Scheme of Ganoderma Lucidum Spore Powder for Postoperative Chemotherapy of Osteosarcoma [Phase 2]

Phase II trial update for Ganoderma Lucidum Spore Powder as postoperative chemotherapy for osteosarcoma (Phase 2).

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