Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults With Refractory Sarcomas, Wilms Tumor, and Other Rare Tumors

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT02867592

Title field or adapter rule

protocolSection.identificationModule.officialTitle

Ingested At

2026-04-25T22:27:57.791811+00:00

Published At

2022-11-28T00:00:00+00:00

Record Updated At

2026-04-13

Results Posted At

2022-11-28

Timestamp Basis

source retrieval time was not retained by the feed adapter

Date limitation

source retrieval time was not retained by the feed adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Adrenal Cortical Carcinoma", "Alveolar Soft Part Sarcoma", "Central Nervous System Neoplasm", "Childhood Clear Cell Sarcoma of Soft Tissue", "Clear Cell Sarcoma of Soft Tissue", "Ewing Sarcoma", "Hepatoblastoma", "Hepatocellular Carcinoma", "Osteosarcoma", "Recurrent Adrenal Cortical Carcinoma", "Recurrent Alveolar Soft Part Sarcoma", "Recurrent Clear Cell Sarcoma of Soft Tissue", "Recurrent Ewing Sarcoma", "Recurrent Hepatoblastoma", "Recurrent Hepatocellular Carcinoma", "Recurrent Kidney Wilms Tumor", "Recurrent Malignant Solid Neoplasm", "Recurrent Osteosarcoma", "Recurrent Primary Malignant Central Nervous System Neoplasm", "Recurrent Renal Cell Carcinoma", "Recurrent Rhabdomyosarcoma", "Recurrent Soft Tissue Sarcoma", "Recurrent Thyroid Gland Medullary Carcinoma", "Refractory Adrenal Cortical Carcinoma", "Refractory Alveolar Soft Part Sarcoma", "Refractory Clear Cell Sarcoma of Soft Tissue", "Refractory Ewing Sarcoma", "Refractory Hepatoblastoma", "Refractory Hepatocellular Carcinoma", "Refractory Malignant Solid Neoplasm", "Refractory Osteosarcoma", "Refractory Primary Central Nervous System Neoplasm", "Refractory Primary Malignant Central Nervous System Neoplasm", "Refractory Renal Cell Carcinoma", "Refractory Rhabdomyosarcoma", "Refractory Soft Tissue Sarcoma", "Refractory Thyroid Gland Medullary Carcinoma", "Refractory Wilms Tumor", "Renal Cell Carcinoma", "Rhabdomyosarcoma", "Soft Tissue Sarcoma", "Solid Neoplasm", "Thyroid Gland Medullary Carcinoma", "Wilms Tumor"]

protocolSection.statusModule.lastUpdatePostDateStruct.date

"2026-04-13"

protocolSection.identificationModule.nctId

"NCT02867592"

protocolSection.identificationModule.officialTitle

"Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults With Refractory Sarcomas, Wilms Tumor, and Other Rare Tumors"

protocolSection.statusModule.overallStatus

"ACTIVE_NOT_RECRUITING"

protocolSection.designModule.phases

["PHASE2"]

protocolSection.statusModule.resultsFirstPostDateStruct.date

"2022-11-28"

Study condition terms

• Adrenal Cortical Carcinoma (protocolSection.conditionsModule.conditions)
• Alveolar Soft Part Sarcoma (protocolSection.conditionsModule.conditions)
• Central Nervous System Neoplasm (protocolSection.conditionsModule.conditions)
• Childhood Clear Cell Sarcoma of Soft Tissue (protocolSection.conditionsModule.conditions)
• Clear Cell Sarcoma of Soft Tissue (protocolSection.conditionsModule.conditions)
• Ewing Sarcoma (protocolSection.conditionsModule.conditions)
• Hepatoblastoma (protocolSection.conditionsModule.conditions)
• Hepatocellular Carcinoma (protocolSection.conditionsModule.conditions)
• Osteosarcoma (protocolSection.conditionsModule.conditions)
• Recurrent Adrenal Cortical Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Alveolar Soft Part Sarcoma (protocolSection.conditionsModule.conditions)
• Recurrent Clear Cell Sarcoma of Soft Tissue (protocolSection.conditionsModule.conditions)
• Recurrent Ewing Sarcoma (protocolSection.conditionsModule.conditions)
• Recurrent Hepatoblastoma (protocolSection.conditionsModule.conditions)
• Recurrent Hepatocellular Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Kidney Wilms Tumor (protocolSection.conditionsModule.conditions)
• Recurrent Malignant Solid Neoplasm (protocolSection.conditionsModule.conditions)
• Recurrent Osteosarcoma (protocolSection.conditionsModule.conditions)
• Recurrent Primary Malignant Central Nervous System Neoplasm (protocolSection.conditionsModule.conditions)
• Recurrent Renal Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Rhabdomyosarcoma (protocolSection.conditionsModule.conditions)
• Recurrent Soft Tissue Sarcoma (protocolSection.conditionsModule.conditions)
• Recurrent Thyroid Gland Medullary Carcinoma (protocolSection.conditionsModule.conditions)
• Refractory Adrenal Cortical Carcinoma (protocolSection.conditionsModule.conditions)
• Refractory Alveolar Soft Part Sarcoma (protocolSection.conditionsModule.conditions)
• Refractory Clear Cell Sarcoma of Soft Tissue (protocolSection.conditionsModule.conditions)
• Refractory Ewing Sarcoma (protocolSection.conditionsModule.conditions)
• Refractory Hepatoblastoma (protocolSection.conditionsModule.conditions)
• Refractory Hepatocellular Carcinoma (protocolSection.conditionsModule.conditions)
• Refractory Malignant Solid Neoplasm (protocolSection.conditionsModule.conditions)
• Refractory Osteosarcoma (protocolSection.conditionsModule.conditions)
• Refractory Primary Central Nervous System Neoplasm (protocolSection.conditionsModule.conditions)
• Refractory Primary Malignant Central Nervous System Neoplasm (protocolSection.conditionsModule.conditions)
• Refractory Renal Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Refractory Rhabdomyosarcoma (protocolSection.conditionsModule.conditions)
• Refractory Soft Tissue Sarcoma (protocolSection.conditionsModule.conditions)
• Refractory Thyroid Gland Medullary Carcinoma (protocolSection.conditionsModule.conditions)
• Refractory Wilms Tumor (protocolSection.conditionsModule.conditions)
• Renal Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Rhabdomyosarcoma (protocolSection.conditionsModule.conditions)
• Soft Tissue Sarcoma (protocolSection.conditionsModule.conditions)
• Solid Neoplasm (protocolSection.conditionsModule.conditions)
• Thyroid Gland Medullary Carcinoma (protocolSection.conditionsModule.conditions)
• Wilms Tumor (protocolSection.conditionsModule.conditions)

Intervention details are not present in the imported fields for this record. No drug-condition relationship is inferred from co-listing.

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