Osteosarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma [Phase 1]
A Phase 1 trial of tegavivint with gemcitabine in relapsed or refractory osteosarcoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma [Phase 3]
This Phase 3 clinical trial assesses thoracotomy versus thoracoscopic management of pulmonary metastases in patients with osteosarcoma and i…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety and potential efficacy of PEEL-224 in combination with vincristine and temozolomide in a…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas [NA]
Investigates regorafenib as maintenance therapy after first-line treatment in patients with bone sarcomas and related subtypes. The trial is…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients [Phase 2]
This clinical trial update notes ongoing Phase 2 evaluation of regorafenib plus best supportive care as maintenance therapy for high-grade b…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial [Phase 1]
A Phase 1 study investigating FH-FOLR1 ST CAR T cells for advanced, refractory, or recurrent osteosarcoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Iscador® P (Mistletoe) Immunotherapy for Recurrent Osteogenic Sarcoma [Phase 2]
This Phase 2 clinical trial is evaluating Iscador P (mistletoe) immunotherapy for recurrent osteosarcoma and the study is currently recruiti…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas [Phase 1]
Phase 1 clinical trial in pediatric relapsed/refractory sarcomas evaluating hypofractionated radiation in combination with B7-H3-CAR T cells…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy) [Phase 1, Phase 2]
The document notes that Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy) is currently recruiting Phase 1/2 trials for relapsed or refractory o…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: SPEARHEAD-3 Pediatric Study [Phase 1, Phase 2]
SPEARHEAD-3 is a pediatric study enrolling in Phase 1 and Phase 2 across multiple cancers, including synovial sarcoma, malignant peripheral …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Pediatric PET/MR Image Registry
A pediatric PET/MR image registry is currently recruiting to collect imaging data for soft tissue sarcoma, lymphoma, and osteosarcoma.
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma [Phase 1]
Phase 1 trial evaluating NKG2D.Zeta-NK cell conditioning combined with C7R.GD2.CAR-T cells in patients with relapsed or refractory neuroblas…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning [NA]
A clinical study sponsored by Ricoh USA, Inc. is evaluating the use of 3D-printed models to assist pre-operative planning for various sarcom…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence [NA]
This clinical trial update describes long-term brain toxicity from chemotherapy in adults who were treated for osteosarcoma or Ewing sarcoma…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: An Organoid-based Functional Precision Medicine Trial in Osteosarcoma
A clinical trial in osteosarcoma evaluating organoid-based functional precision medicine is currently recruiting, sponsored by the Jonsson C…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Gemcitabine, Docetaxel, and Hydroxychloroquine in Treating Participants With Recurrent or Refractory Osteosarcoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating gemcitabine, docetaxel, and hydroxychloroquine for recurrent or refractory osteosarcoma; the study is cu…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas [NA]
A completed clinical trial update examining diffusion-weighted MRI imaging in younger patients with newly diagnosed bone or soft-tissue sarc…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Losartan + Sunitinib in Treatment of Osteosarcoma [Phase 1]
Phase 1 trial investigating the combination of Losartan and Sunitinib for osteosarcoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage Surgery
This clinical trial update notes a study evaluating adherence to a personalized home exercise program for bone tumor patients undergoing low…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Biomarkers of Resiliency In Childhood Cancer Surgery
Clinical trial update from Mayo Clinic on biomarkers of resiliency in pediatric cancer surgery, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma [Phase 1]
Phase 1 clinical trial evaluating HER2-targeted CAR T cells in combination with checkpoint blockade for advanced sarcoma; recruitment is ong…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: PET-imaging of Two Vartumabs in Patients With Solid Tumors [EARLY_Phase 1]
This early-phase PET-imaging trial evaluates two vartumabs in patients with solid tumors and is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Mifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients [Phase 2]
Phase 2 clinical trial evaluating mifamurtide with postoperative chemotherapy for newly diagnosed high-risk osteosarcoma. The study is curre…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma [Phase 1]
Phase 1 clinical trial evaluating allogeneic expanded gamma delta T cells combined with GD2-targeted chemoimmunotherapy in relapsed/refracto…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Biology of Osteosarcoma (BOOST) Registry and Biobank
The BOOST Registry and Biobank for osteosarcoma has completed data collection and resource assembly, as reported by the University of Minnes…