Clinical Trial Update: HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma [Phase 1]

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Summary

Phase 1 clinical trial evaluating HER2-targeted CAR T cells in combination with checkpoint blockade for advanced sarcoma; recruitment is ongoing.

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Diseases / indications

• Ewing Sarcoma
• Osteosarcoma
• Rhabdomyosarcoma
• Sarcoma
• Soft Tissue Sarcoma
• Synovial Sarcoma
• Undifferentiated Pleomorphic Sarcoma

Drugs mentioned

• HER2-targeted CAR T cells (HER2-targeted CAR T cells)

Snippet

Sponsor: Baylor College of Medicine | Conditions: Sarcoma, HER-2 Protein Overexpression | Phase 1 | Status: RECRUITING