Myeloproliferative Neoplasm
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update. It evaluates a conditioning strategy using chemotherapy, total body irradiation, and post-transpl…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms [Phase 1]
Phase 1 study evaluating FLAG-Ida chemotherapy plus pivekimab sunirine (IMGN632) for newly diagnosed adverse-risk acute myeloid leukemia and…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy [Phase 1]
This clinical trial update describes a Phase 1 study of edetate calcium disodium or succimer in patients with acute myeloid leukemia or myel…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes [Phase 2]
Phase 2 trial evaluating adding pomalidomide to the standard liposomal daunorubicin/cytarabine chemotherapy in newly diagnosed acute myeloid…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms [Phase 2]
Phase 2 study evaluating venetoclax in combination with azacitidine in advanced BCR-ABL negative myeloproliferative neoplasms is currently r…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Maintenance Fedratinib to Prevent Post-Transplant Relapse in Myeloproliferative Neoplasms [Phase 1]
A Phase 1 trial evaluating maintenance fedratinib to prevent post-transplant relapse in myeloproliferative neoplasms has been terminated.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers [Phase 2]
Phase 2 trial evaluating Dexrazoxane hydrochloride to prevent heart-related side effects of chemotherapy in people with blood cancers; the s…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Safety of Flonoltinib Maleate Tablets for the Treatment of Patients With Myeloproliferative [Phase 1, Phase 2]
This clinical trial update reports safety findings from Phase 1/2 studies of Flonoltinib Maleate Tablets in patients with myeloproliferative…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Haplo Peripheral Blood Sct In GVHD Prevention [Phase 1]
Phase 1 trial update reporting the completion of a haploidentical peripheral blood stem cell transplantation approach for the prevention of …
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Intra-patient Dose Escalation Study to Investigate Safety and Feasibility of Vactosertib in Treating Anemic MPN Patients [Phase 2]
Phase 2 intra-patient dose-escalation trial assessing the safety and feasibility of Vactosertib in anemic myeloproliferative neoplasm patien…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome [Phase 3]
Phase 3 trial evaluating response-based chemotherapy in younger patients with Down syndrome who have newly diagnosed acute myeloid leukemia …
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT Study
This completed clinical trial (NCT05053100) investigates the risk of blood clots and bleeding in patients with hematologic cancers.
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Evaluation of CPX-351 Monotherapy in Acute Myeloid Leukemia Secondary to Myeloproliferative Neoplasm [Phase 2]
Phase 2 evaluation of CPX-351 monotherapy in acute myeloid leukemia secondary to myeloproliferative neoplasm has completed.
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms [Phase 1]
The Phase 1 study of TAS1553 in subjects with relapsed or refractory acute myeloid leukemia and other myeloid neoplasms has been terminated.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Allo HSCT Using RIC for Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning for various hematologic dise…
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: 2018-0674 - IL-7 for T-Cell Recovery Post Haplo and CB Transplant - Phase I/II [Phase 1, Phase 2]
This Phase I/II clinical trial evaluated Interleukin-7 for T-cell recovery after haploidentical and cord blood stem cell transplantation and…
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating high-dose cyclophosphamide, tacrolimus, and mycophenolate mofetil to prevent graft-versus-host disease in …
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease [Phase 2]
Phase 2 clinical trial investigating salsalate, venetoclax, and decitabine or azacitidine for acute myeloid leukemia and advanced myelodyspl…
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention [Phase 3]
Phase 3 trial comparing Tacrolimus plus mini-methotrexate versus Tacrolimus plus methotrexate for graft-versus-host disease prevention has c…
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CLINICAL_TRIALS trial_result · 2023-01-10Clinical Trial Update: Decidual Stromal Cells to Treat Graft-vs-Host Disease After Stem Cell Transplant for Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 2]
Phase 2 trial evaluating decidual stromal cells for treatment of steroid-refractory graft-versus-host disease after allogeneic stem cell tra…
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CLINICAL_TRIALS trial_result · 2022-06-22Clinical Trial Update: Remotely Administered Diet Intervention to Impact Symptom Burden in Myeloproliferative Neoplasm [Phase 2]
Phase 2 clinical trial evaluating a remotely administered diet intervention to reduce symptom burden in patients with myeloproliferative neo…
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CLINICAL_TRIALS trial_result · 2021-08-11Clinical Trial Update: TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid [Phase 2]
Phase 2 trial updating TET2 mutation targeting with azacitidine plus ascorbic acid in myelodysplastic syndromes and acute myeloid leukemia h…
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CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma [Phase 2]
Phase 2 trial evaluating CD8+ memory T-cells as consolidative therapy after donor non-myeloablative hematopoietic cell transplant in leukemi…
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms [Phase 1, Phase 2]
Phase 1b/2 trial assessing APR-246 plus azacitidine in TP53-mutant myeloid neoplasms completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-10-11Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.