Myeloproliferative Neoplasm
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes Overlap Syndromes (ABNL-MARRO) [Phase 1, Phase 2]
A clinical trial update on active myeloid-target compound combinations for myelodysplastic syndromes with myeloproliferative neoplasm overla…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Azacitidine and Quizartinib for the Treatment of Myelodysplastic Syndrome or Myelodysplastic/Myeloproliferative Neoplasm With FLT3 or CBL Mutations [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of azacitidine and quizartinib for patients with chronic myelomonocytic leukemia, myel…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations [Phase 2]
This entry outlines a Phase 2 clinical trial testing olutasidenib in combination with a co-targeted therapy for relapsed or refractory IDH1-…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Mechanism of Action of Interferon in the Treatment of Myeloproliferative Neoplasms
This clinical trial investigates the mechanism of action of interferon in the treatment of myeloproliferative neoplasms and is currently rec…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 2]
Clinical trial update of a Phase 2 study evaluating venetoclax in combination with ASTX727 (oral decitabine/cedazuridine) for chronic myelom…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms [Phase 2]
A Phase 2 clinical trial evaluating decitabine in combination with JAK inhibitors (ruxolitinib, fedratinib, or pacritinib) for accelerated o…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS) [Phase 2]
This is a Phase 2 clinical trial update evaluating strategies to reduce graft-versus-host disease in donor blood stem cell transplant patien…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating combinations of ivosidenib and venetoclax with or without azacitidine in IDH1-mutated hematologic mali…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Evaluation of the Pathobiology of CALR-mutated MPN Cells
Clinical trial investigating the pathobiology of CALR-mutated myeloproliferative neoplasm cells; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care [NA]
This clinical trial update describes a University of Miami-sponsored study evaluating how Leukemia & Lymphoma Society services affect patien…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms [Phase 1]
Phase 1 clinical trial evaluating a triple combination of navitoclax, venetoclax, and decitabine for advanced myeloid neoplasms. The study i…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation [Phase 1]
Phase 1 clinical trial evaluating preemptive CIML NK cell therapy after hematopoietic stem cell transplantation in patients with acute myelo…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Polycythemia Vera [Phase 4]
This clinical trial update reports on a Phase 4 study of Ropeginterferon alfa-2b (P1101) for polycythemia vera, focusing on efficacy and saf…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning [Phase 2]
Phase 2 trial evaluating vedolizumab with post-transplant cyclophosphamide and tacrolimus to prevent graft-versus-host disease in patients u…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants [Phase 2]
Phase 2 clinical trial update describing the addition of itacitinib to cyclophosphamide and tacrolimus for preventing graft-versus-host dise…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Determination of the Clonality Profile in Myeloproliferative Neoplasms and Association With the Thrombotic Complications (CLOJAK)
This ClinicalTrials.gov entry describes the CLOJAK study, a recruiting trial evaluating clonality profiles in myeloproliferative neoplasms a…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Study of IMGN632 in Patients With Untreated BPDCN and Relapsed/Refractory BPDCN [Phase 1, Phase 2]
An ongoing Phase 1/2 trial of IMGN632 for untreated and relapsed/refractory Blastic plasmacytoid dendritic cell neoplasm. The study is curre…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Vitamin A and D Supplementation in Allogeneic HCT [Phase 2]
Phase 2 clinical trial in allogeneic hematopoietic cell transplantation is evaluating vitamin A and vitamin D supplementation, currently rec…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Exploring the Impact of Monocytes in Myeloproliferative Neoplasia (EMYNEM)
A recruiting clinical trial investigating the role of monocytes in myeloproliferative neoplasms. The study is sponsored by University Hospit…
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CLINICAL_TRIALS research · 2017-03-03Clinical Trial Update: Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis [Phase 3]
A Phase 3 trial comparing cyclophosphamide with methotrexate plus a calcineurin inhibitor for GVHD prophylaxis in patients with various hema…
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CLINICAL_TRIALS research · 2015-06-16Clinical Trial Update: A Case Control Study of the Prevalence of Pulmonary Hypertension in Patients With Myeloproliferative Diseases.
This clinical trial update describes a case-control study at Carmel Medical Center investigating how common pulmonary hypertension is among …